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Parthenin
Parthenin is a chemical compound classified as a sesquiterpene lactone. It has been isolated from ''Parthenium hysterophorus''. It is genotoxic, allergenic, and an irritant. Parthenin is believed to be responsible for the dermatitis caused by ''Parthenium hysterophorus''. References

sesquiterpene lactones Vinylidene compounds {{organic-compound-stub ...
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Parthenium Hysterophorus
''Parthenium hysterophorus'' is a species of flowering plant in the family Asteraceae. It is native to the American tropics. Common names include Santa-Maria, Santa Maria feverfew, whitetop weed, and famine weed.McConnachie AJ, Strathie LW, et al. Current and potential geographical distribution of the invasive plant Parthenium hysterophorus (Asteraceae) in eastern and southern Africa. Weed Research. 2011 51(1) From http://www.farmersweekly.co.za 27 December 2013 In India, it is locally known as carrot grass, congress grass or ''Gajar Ghas''. It is a common invasive species in India, Australia, and parts of Africa. Invasive species ''Parthenium hysterophorus'' invades disturbed land, including roadsides. It infests pastures and farmland, causing often disastrous loss of yield, as reflected in common names such as ''famine weed''. In some areas, heavy outbreaks have been ubiquitous, affecting livestock and crop production, and human health. The plant produces allelopathic ...
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Sesquiterpene Lactone
Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) and Magnoliaceae (magnolias). A collection of colorless, lipophilic solids, SLs are a rich source of drugs. They can be allergenic and toxic in grazing livestock causing severe neurological problems in horses. Some are also found in corals such as ''Maasella edwardsi''. Types Sesquiterpene lactones can be divided into several main classes including germacranolides, heliangolides, guaianolides, pseudoguaianolides, hypocretenolides, and eudesmanolides. Examples Artemisinin, a new, highly-effective anti- malarial compound, is a sesquiterpene lactone found in '' Artemisia annua''. Lactucin, desoxylactucin, lactucopicrin, lactucin-15-oxalate, lactucopicrin-15-oxalate are some of the most prominent found in lettuce and spina ...
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Dermatitis
Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to covering the entire body. Dermatitis is often called eczema, and the difference between those terms is not standardized. The exact cause of the condition is often unclear. Cases may involve a combination of allergy and poor venous return. The type of dermatitis is generally determined by the person's history and the location of the rash. For example, irritant dermatitis often occurs on the hands of those who frequently get them wet. Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin. Prevention of atopic dermatitis is typically with essential fatty acids, and may be treated with moisturizers and steroid creams. The steroid creams should generally be of ...
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Sesquiterpene Lactones
Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) and Magnoliaceae (magnolias). A collection of colorless, lipophilic solids, SLs are a rich source of drugs. They can be allergenic and toxic in grazing livestock causing severe neurological problems in horses. Some are also found in corals such as ''Maasella edwardsi''. Types Sesquiterpene lactones can be divided into several main classes including germacranolides, heliangolides, guaianolides, pseudoguaianolides, hypocretenolides, and eudesmanolides. Examples Artemisinin, a new, highly-effective anti-malarial compound, is a sesquiterpene lactone found in '' Artemisia annua''. Lactucin, desoxylactucin, lactucopicrin, lactucin-15-oxalate, lactucopicrin-15-oxalate are some of the most prominent found in lettuce and spinach, gi ...
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