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Paramyxovirus Genome Structure
Paramyxovirus can refer to two different groups of viruses: *a member of the family ''Paramyxoviridae ''Paramyxoviridae'' (from Greek ''para-'' “by the side of” and ''myxa'' “mucus”) is a family of negative-strand RNA viruses in the order '' Mononegavirales''. Vertebrates serve as natural hosts. Diseases associated with this family includ ...'' can be called a paramyxovirus (no italics) *the genus '' Respirovirus'' was known as ''Paramyxovirus'' (with italics) until 1998 {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paramyxoviridae
''Paramyxoviridae'' (from Greek ''para-'' “by the side of” and ''myxa'' “mucus”) is a family of negative-strand RNA viruses in the order '' Mononegavirales''. Vertebrates serve as natural hosts. Diseases associated with this family include measles, mumps, and respiratory tract infections. The family has four subfamilies, 17 genera, and 78 species, three genera of which are unassigned to a subfamily. Structure Virions are enveloped and can be spherical or pleomorphic and capable of producing filamentous virions. The diameter is around 150 nm. Genomes are linear, around 15kb in length. Fusion proteins and attachment proteins appear as spikes on the virion surface. Matrix proteins inside the envelope stabilise virus structure. The nucleocapsid core is composed of the genomic RNA, nucleocapsid proteins, phosphoproteins and polymerase proteins. Genome The genome is nonsegmented, negative-sense RNA, 15–19 kilobases in length, and contains six to 10 genes. Extraci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
