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Paglicci 23
Paglicci 23 is the name for human remains found in Paglicci Cave in Apulia, Italy that have been dated to 28,000 years Before Present. In 2008 a scientific team led by David Caramelli tested Paglicci 23 and found that mtDNA sequences corresponding to positions 16024-16383 were identical to the Cambridge Reference Sequence. The result was exhaustively tested for possible contamination and replicated in a separate test. The paper does not assign any mtDNA haplogroup to the results as the mtDNA segment is too small to draw any conclusions in this regard. Many haplogroups, however, are defined by mutations in this segment as indicated in the table below. As a result, the sample can confirm that the mtDNA does not correspond to any of the above modern extant haplogroups. The sample is however confirmed to belong to haplogroup R: 16263 is a critical marker for haplogroup R. The sample does not rule out nor confirm that the sample may belong to haplogroup H as this group is distingu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cadaver
A cadaver or corpse is a dead human body that is used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue to repair a defect in a living human being. Students in medical school study and dissect cadavers as a part of their education. Others who study cadavers include archaeologists and arts students. The term ''cadaver'' is used in courts of law (and, to a lesser extent, also by media outlets such as newspapers) to refer to a dead body, as well as by recovery teams searching for bodies in natural disasters. The word comes from the Latin word ''cadere'' ("to fall"). Related terms include ''cadaverous'' (resembling a cadaver) and '' cadaveric spasm'' (a muscle spasm causing a dead body to twitch or jerk). A cadaver graft (also called “postmortem graft”) is the grafting of tissue from a dead body onto a living human to repair a defect or disfigurement. Cadavers can be observed for their ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paglicci Cave
Paglicci Cave is an archaeological site situated in Paglicci, near Rignano Garganico, Apulia, southern Italy. The cave, discovered in the 1950s, is the most important cave of Gargano. The cave is an attraction of the Gargano National Park. Description In the cave, situated near Rignano Garganico, there are more than 45,000 individual finds, including Paleolithic tools, human and animal bones. They are currently housed in Rignano Garganico's Museum. Evidence of paleolithic oat harvesting dating to 30,600 BC was linked to a pestle recovered from the cave. The cave contains also some Paleolithic mural paintings, depicting horses and handprints. Images of goats, cows, a serpent, a nest with eggs, and a hunting scene have also been found engraved on bone. Two human skeletons have been found as well, belonging to a boy and a young woman, both wearing deer bone or teeth ornaments. Paglicci cave contains the earliest Aurignacian and Gravettian remains of Italy, dated to c. 34,000 a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apulia
Apulia ( ), also known by its Italian name Puglia (), :: nap, label=, Puie :: nap, label=Tarantino dialect, Tarantino, Puje : scn, label=Salentino dialect, Salentino, Puia : frp, label=Faetar language, Faetar, Poulye : el, label=Griko language, Griko, Απουλία : aae, Pulia. is a Regions of Italy, region of Italy, located in the Southern Italy, southern peninsular section of the country, bordering the Adriatic Sea to the east, the Ionian Sea to the southeast and the Strait of Otranto and Gulf of Taranto to the south. The region comprises , and its population is about four million people. It is bordered by the other Italian regions of Molise to the north, Campania to the west, and Basilicata to the southwest. Its chief town is Bari. Geography Apulia's coastline is longer than that of any other mainland Italian region. In the north, the Gargano promontory extends out into the Adriatic sea like a 'sperone' ("spur"), while in the south, the Salento peninsula forms the 'tacc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Italy
Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical region. Italy is also considered part of Western Europe, and shares land borders with France, Switzerland, Austria, Slovenia and the enclaved microstates of Vatican City and San Marino. It has a territorial exclave in Switzerland, Campione. Italy covers an area of , with a population of over 60 million. It is the third-most populous member state of the European Union, the sixth-most populous country in Europe, and the tenth-largest country in the continent by land area. Italy's capital and largest city is Rome. Italy was the native place of many civilizations such as the Italic peoples and the Etruscans, while due to its central geographic location in Southern Europe and the Mediterranean, the country has also historically b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Before Present
Before Present (BP) years, or "years before present", is a time scale used mainly in archaeology, geology and other scientific disciplines to specify when events occurred relative to the origin of practical radiocarbon dating in the 1950s. Because the "present" time changes, standard practice is to use 1 January 1950 as the commencement date ( epoch) of the age scale. The abbreviation "BP" has been interpreted retrospectively as "Before Physics", which refers to the time before nuclear weapons testing artificially altered the proportion of the carbon isotopes in the atmosphere, which scientists must now account for. In a convention that is not always observed, many sources restrict the use of BP dates to those produced with radiocarbon dating; the alternative notation RCYBP stands for the explicit "radio carbon years before present". Usage The BP scale is sometimes used for dates established by means other than radiocarbon dating, such as stratigraphy. This usage differs from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MtDNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondrion, mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants and algae, also in plastids such as chloroplasts. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. This sequencing revealed that the human mtDNA includes 16,569 base pairs and encodes 13 proteins. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology. It also permits an examination of the relatedness of populations, and so has become important in anthropology and biogeography. Origin Nuclear and mitochondrial DNA are thought to be of separate evolutionary origin, with the mtDNA being ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge Reference Sequence
The Cambridge Reference Sequence (CRS) for human mitochondrial DNA was first announced in 1981. A group led by Fred Sanger at the University of Cambridge had sequenced the mitochondrial genome of one woman of European descent during the 1970s, determining it to have a length of 16,569 base pairs (0.0006% of the nuclear human genome) containing some 37 genes and published this sequence in 1981. When other researchers repeated the sequencing, some striking discrepancies were noted. The original published sequence included eleven errors, including one extra base pair in position 3107, and incorrect assignments of single base pairs. Some of these were the result of contamination with bovine and HeLa specimens. The corrected revised CRS was published by Andrews et al. in 1999. (The original nucleotide numbering was retained to avoid confusion.) The reference sequence belongs to European haplogroup H2a2a1. The revised CRS is designated as rCRS. It is deposited in the GenBank NCBI ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Mitochondrial DNA Haplogroup
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in Human mitochondrial genetics, human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineality, matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor, most recent common ancestor (MRCA) for world population, all currently living humans. She is commonly calle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup R (mtDNA)
Haplogroup R is a widely distributed human mitochondrial DNA (mtDNA) haplogroup. Haplogroup R is associated with the peopling of Eurasia after about 70,000 years ago, and is distributed in modern populations throughout the world outside of sub-Saharan Africa. Haplogroup R is a descendant of the macro- haplogroup N. Among the R clade's descendant haplogroups are B, U (and thus K), F, R0 (and thus HV, H, and V), and JT (the ancestral haplogroup of J and T). Origin Soares et al. (2009) estimate the age of haplogroup R at roughly 50,000 to 70,000 years ago. This is consistent with an emergence in the course of the Coastal Migration out of East Africa to West, South and Southeast Asia. It has been suggested that the early lineage of haplogroups M, N and R along the coastal route during the period of roughly 70,000 to 60,000 years ago. Haplogroup R has wide diversity and antiquity in the indigenous population of South Asia. Tribes and castes of Western and Southern ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup H (mtDNA)
Haplogroup H is a human mitochondrial DNA (mtDNA) haplogroup. The clade is believed to have originated in Southwest Asia, near present day Syria, around 20,000 to 25,000 years ago. Mitochondrial haplogroup H is today predominantly found in Europe, and is believed to have evolved before the Last Glacial Maximum (LGM). It first expanded in the northern Near East and Southern Caucasus soon, and later migrations from Iberia suggest that the clade reached Europe before the Last Glacial Maximum. The haplogroup has also spread to parts of Africa, Siberia and inner Asia. Today, around 40% of all maternal lineages in Europe belong to haplogroup H. Origin Haplogroup H is a descendant of haplogroup HV. The Cambridge Reference Sequence (CRS), which until recently was the human mitochondrial sequence to which all others were compared, belongs to haplogroup H2a2a1 (human mitochondrial sequences should now be compared with the ancestral Reconstructed Sapiens Reference Sequence (RSRS)). S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of DNA Tested Mummies
This is a purported list of ancient humans remains, including mummies, that may have been DNA tested. Provided as evidence of the testing are links to the mitochondrial DNA sequences, and/or to the human haplogroups to which each case has been assigned. Also provided is a brief description of when and where they lived. Entries lacking a citation should be viewed with skepticism; in particular, cases with no sequence or haplogroup links, with citation, have no evidentiary basis for appearing. mtDNA tests The following mummies have undergone an mtDNA ( mitochondrial DNA) test, of remains with the indicated name, from the indicated locations: DNA tests The following mummies have undergone DNA tests, of remains with the indicated name, from the indicated locations: See also *Ancient DNA *Cambridge Reference Sequence *Human mitochondrial DNA haplogroup * List of genetic results derived from historical figures * List of mummies References Further reading * * ''The Seven Da ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient DNA
Ancient DNA (aDNA) is DNA isolated from ancient specimens. Due to degradation processes (including cross-linking, deamination and fragmentation) ancient DNA is more degraded in comparison with contemporary genetic material. Even under the best preservation conditions, there is an upper boundary of 0.4–1.5 million years for a sample to contain sufficient DNA for sequencing technologies. The oldest sample ever sequenced is estimated to be 1.65 million years old. Genetic material has been recovered from paleo/archaeological and historical skeletal material, mummified tissues, archival collections of non-frozen medical specimens, preserved plant remains, ice and from permafrost cores, marine and lake sediments and excavation dirt. On 7 December 2022, '' The New York Times'' reported that two-million year old genetic material was found in Greenland, and is currently considered the oldest DNA discovered so far. History of ancient DNA studies 1980s The first study of what would ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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