PKD Media
{{disambiguation ...
PKD may stand for: * Philip K. Dick (1928–1982), American science fiction writer * ICAO PKD, the International Civil Aviation Organization Public Key Directory * Paroxysmal kinesigenic dyskinesia, a movement disorder * Pi Kappa Delta, a forensics honor society * Polycystic kidney disease * PKD1 and PKD2, human genes * Proliferative kidney disease, caused by the parasite '' Tetracapsuloides'' * Proto-Kra–Dai language Proto-Kra–Dai (typically abbreviated as PKD) is the proposed reconstructed ancestor of the Kra–Dai languages. Background No full reconstruction of Proto-Kra–Dai has been published to date, although tentative reconstructions of many Proto-K ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Philip K
Philip, also Phillip, is a male given name, derived from the Greek language, Greek (''Philippos'', lit. "horse-loving" or "fond of horses"), from a compound of (''philos'', "dear", "loved", "loving") and (''hippos'', "horse"). Prominent Philips who popularized the name include List of kings of Macedonia, kings of Macedonia and one of the apostles of early Christianity. ''Philip'' has #Philip in other languages, many alternative spellings. One derivation often used as a surname is Phillips (surname), Phillips. It was also found during ancient Greek times with two Ps as Philippides (other), Philippides and Philippos. It has many diminutive (or even hypocorism, hypocoristic) forms including Phil, Philly (other)#People, Philly, Lip (other), Lip, Pip (other), Pip, Pep (other), Pep or Peps. There are also feminine forms such as Philippine de Rothschild, Philippine and Philippa. Antiquity Kings of Macedon * Philip I of Macedon * Philip II ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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ICAO PKD
The International Civil Aviation Organization Public Key Directory (ICAO PKD) is a database maintained by the International Civil Aviation Organization holding national cryptographic keys related to the authentication of e-passport information. A September 2011 United States Central Intelligence Agency document released by WikiLeaks in December 2014 explains the purpose and scope of the system: The United Nations became the first non-state participant in October 2012, enabling issuing of e-UNLP, the electronic form of the United Nations laissez-passer. In December 2014, ICAO reported the PKD as having 45 participants. In 2015 the German Bundesdruckerei (German Federal Printing Office) won the request for tender of the ICAO to provide the ICAO PKD. In July 2017, ICAO reported the PKD as having 58 participants. As of November 2017, 60 participants were part of the ICAO PKD, with the European Union being the 60th member and at the same time the second non-state participant. Se ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Paroxysmal Kinesigenic Choreoathetosis
Paroxysmal kinesigenic choreoathetosis (PKC) also called paroxysmal kinesigenic dyskinesia (PKD) is a hyperkinetic movement disorder characterized by attacks of involuntary movements, which are triggered by sudden voluntary movements. The number of attacks can increase during puberty and decrease in a person's 20s to 30s. Involuntary movements can take many forms such as ballism, chorea or dystonia and usually only affect one side of the body or one limb in particular. This rare disorder only affects about 1 in 150,000 people, with PKD accounting for 86.8% of all the types of paroxysmal dyskinesias, and occurs more often in males than females. There are two types of PKD, primary and secondary. Primary PKD can be further broken down into familial and sporadic. Familial PKD, which means the individual has a family history of the disorder, is more common, but sporadic cases are also seen. Secondary PKD can be caused by many other medical conditions such as multiple sclerosis (MS), ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pi Kappa Delta
Pi Kappa Delta () is a Forensics (Public Speaking and Debate) Honor Society for undergraduate university students and a professional organization for graduates, typically university Speech and Debate Coaches. Pi Kappa Delta, or PKD, encourages the education of articulate citizens through a three part focus: the commitment to and promotion of ethical, humane and inclusive communication and educational practices; the commitment to and promotion of professional development of forensics educators; and the commitment to and promotion of comprehensive forensics programming. More than 60,000 men and women have been initiated into PKD. Active chapters are located on more than 200 college and university campuses. Schools in PKD range in size from some of the largest universities to some of the smaller liberal arts colleges, teaching colleges, and church related colleges. Programs and Initiatives National Convention PKD sponsors a National Convention every other year at which time the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Polycystic Kidney Disease
Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. These cysts may begin to develop in utero, in infancy, in childhood, or in adulthood. Cysts are non-functioning tubules filled with fluid pumped into them, which range in size from microscopic to enormous, crushing adjacent normal tubules and eventually rendering them non-functional as well. PKD is caused by abnormal genes that produce a specific abnormal protein; this protein has an adverse effect on tubule development. PKD is a general term for two types, each having their own pathology and genetic cause: autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). The abnormal gene exists in all cells in the body; as a result, cysts may occur in the liver, seminal vesicles, and pancreas. T ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Polycystin 1
Polycystin 1 (often abbreviated to PC1) is a protein that in humans is encoded by the ''PKD1'' gene. Mutations of ''PKD1'' are associated with most cases of autosomal dominant polycystic kidney disease, a severe hereditary disorder of the kidneys characterised by the development of renal cysts and severe kidney dysfunction. Protein structure and function PC1 is a membrane-bound protein 4303 amino acids in length expressed largely upon the primary cilium, as well as apical membranes, adherens junctions, and desmosomes. It has 11 transmembrane domains, a large extracellular N-terminal domain, and a short (about 200 amino acid) cytoplasmic C-terminal domain. This intracellular domain contains a coiled-coil domain through which PC1 interacts with polycystin 2 (PC2), a membrane-bound Ca2+-permeable ion channel. PC1 has been proposed to act as a G protein–coupled receptor. The C-terminal domain may be cleaved in a number of different ways. In one instance, a ~35 kDa portion of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Polycystin 2
Polycystin-2 is a protein that in humans is encoded by the ''PKD2'' gene. This gene encodes a member of the polycystin protein family, called TRPP2, previously known as polycystin-2, PC2 or APKD2. TRPP2 contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. TRPP2 may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homeostasis and other signal transduction pathways. This protein interacts with polycystin 1 (TRPP1) to produce cation-permeable currents. It was discovered by Stefan Somlo at Yale University. Clinical significance Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. Interactions Polycystin 2 has been shown to interact with the proteins TRPC1, PKD1 and TNNI3 Troponin I, cardiac muscle is a protein that in humans is encoded by the ''TNNI3'' gene. It is a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tetracapsuloides
''Tetracapsuloides bryosalmonae'' is a myxozoan parasite of salmonid fish. It is the only species currently recognized in the monotypic genus ''Tetracapsuloides''. It is the cause of proliferative kidney disease (PKD), one of the most serious parasitic diseases of salmonid populations in Europe and North America that can result in losses of up to 90% in infected populations. Taxonomy Until the late 1990s, the organism which caused PKD was enigmatic, thus called PKX organism. The causative agent of PKD was recognized as a form of Malacosporean, but the absence of mature spores in salmonid hosts, the lack of fish to fish transmission, and seasonality of the disease suggested that the life cycle of PKX was completed in another host and that infection of salmonids could be accidental. Korotneff observed a myxozoan in the bryozoan, ''Plumatella fungosa'', in 1892, which he described as ''Myxosporidium bryozoides.'' Myxozoan infection of bryozoans was not reported again until 1996. Ecol ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |