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PH-responsive Tumor-targeted Drug Delivery
pH-responsive tumor-targeted drug delivery is a specialized form of targeted drug delivery that utilizes nanoparticles to deliver therapeutic drugs directly to cancerous Tumor microenvironment, tumor tissue while minimizing its interaction with healthy tissue.Muller, R; Keck, C (2004). "Challenges and solutions for the delivery of biotech drugs – a review of drug nanocrystal technology and lipid nanoparticles". ''Journal of Biotechnology''. 113 (1–3): 151–170. Scientists have used drug delivery as a way to modify the pharmacokinetics and targeted action of a drug by combining it with various excipients, drug carriers, and medical devices. These drug delivery systems have been created to react to the pH environment of diseased or cancerous tissues, triggering structural and chemical changes within the drug delivery system. This form of targeted drug delivery is to localize drug delivery, prolongs the drug's effect, and protect the drug from being broken down or eliminat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Targeted Drug Delivery
Targeted drug delivery, sometimes called smart drug delivery, is a method of delivering Pharmaceutical drug, medication to a patient in a manner that increases the Dose (biochemistry), concentration of the medication in some parts of the body relative to others. This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle-mediated drug delivery in order to combat the downfalls of conventional drug delivery. These nanoparticles would be loaded with drugs and targeted to specific parts of the body where there is solely diseased tissue, thereby avoiding interaction with healthy tissue. The goal of a targeted drug delivery system is to prolong, localize, target and have a protected drug interaction with the diseased tissue. The conventional Route of administration, drug delivery system is the absorption of the drug across a biological membrane, whereas the ''targeted release system'' releases the drug in a dosage form. The advantages to the targeted rel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
