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P. N. Rangarajan
Pundi Narasimhan Rangarajan (born 15 April 1963) is an Indian biochemist, virologist and a professor at the department of biochemistry of the Indian Institute of Science. Prof Rangarajan is currently the Chairman of the Department of Biochemistry at Indian Institute of Science. Known for his research on eukaryotic gene expression, Rangarajan is an elected fellow of all the three major Indian science academies viz. National Academy of Sciences, India, Indian Academy of Sciences and Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2007. Biography P. N. Rangarajan, born in Bengaluru in the south Indian state of Karnataka, secured a PhD from the Indian Institute of Science (IISc) in 1989 and did his post doctoral w ...
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Bengaluru
Bangalore (), officially Bengaluru (), is the capital and largest city of the Indian state of Karnataka. It has a population of more than and a metropolitan population of around , making it the third most populous city and fifth most populous urban agglomeration in India, as well as the largest city in South India, and the 27th largest city in the world. Located on the Deccan Plateau, at a height of over above sea level, Bangalore has a pleasant climate throughout the year, with its parks and green spaces earning it the reputation as the "Garden City" of India. Its elevation is the highest among the major cities of India. An aerospace, heavy engineering and electronics hub since the 1960s, Bangalore is widely regarded as the "Silicon Valley of India" because of its role as the nation's leading information technology (IT) exporter.——— In the Ease of Living Index 2020 (published by the Ministry of Housing and Urban Affairs), it was ranked the most livable Indi ...
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IISc Main Building
The Indian Institute of Science (IISc) is a public, deemed, research university for higher education and research in science, engineering, design, and management. It is located in Bengaluru, in the Indian state of Karnataka. The institute was established in 1909 with active support from Jamsetji Tata and thus is also locally known as the ''"Tata Institute"''. It is ranked among the most prestigious academic institutions in India and has the highest citation per faculty among all the universities in the world. It was granted the deemed to be university status in 1958 and the Institute of Eminence status in 2018. History After an accidental meeting between Jamsetji Tata and Swami Vivekananda, on a ship in 1893 where they discussed Tata's plan of bringing the steel industry to India, Tata wrote to Vivekananda five years later: "I trust, you remember me as a fellow-traveller on your voyage from Japan to Chicago. I very much recall at this moment your views on the growth of the ...
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Indian Institute Of Science Education And Research, Thiruvananthapuram
Indian Institute of Science Education and Research, Thiruvananthapuram (abbreviated as IISER Thiruvananthapuram or IISER-TVM) is an autonomous public university located in Thiruvananthapuram, India. The institute is one of the seven IISERs established by the Ministry of Human Resource Development, Government of India, to bridge the gap between research and basic sciences' education at the undergraduate level. The six other IISERs are IISER Bhopal, IISER Kolkata, IISER Mohali, IISER Pune, IISER Tirupati and IISER Berhampur. All IISERs were declared as Institutes of National Importance by the Parliament of India in 2012 through the NIT Amendment Act. IISER Thiruvananthapuram is an autonomous institution that awards Bachelor of Science & Master of Science (BS-MS) dual-degrees, and Doctor of Philosophy (Ph.D.) degrees in Mathematics, Physics, Chemistry and Biology. IISER TVM is to offer five new BS-MS programmes (i2 Sciences) and new 2 year M.Sc programmes in 2021. The campus ...
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ResearchGate
ResearchGate is a European commercial social networking site for scientists and researchers to share papers, ask and answer questions, and find collaborators. According to a 2014 study by ''Nature'' and a 2016 article in '' Times Higher Education'', it is the largest academic social network in terms of active users, although other services have more registered users, and a 2015–2016 survey suggests that almost as many academics have Google Scholar profiles. While reading articles does not require registration, people who wish to become site members need to have an email address at a recognized institution or to be manually confirmed as a published researcher in order to sign up for an account. Members of the site each have a user profile and can upload research output including papers, data, chapters, negative results, patents, research proposals, methods, presentations, and software source code. Users may also follow the activities of other users and engage in discussions with ...
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Google Scholar
Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines. Released in beta in November 2004, the Google Scholar index includes peer-reviewed online academic journals and books, conference papers, theses and dissertations, preprints, abstracts, technical reports, and other scholarly literature, including court opinions and patents. Google Scholar uses a web crawler, or web robot, to identify files for inclusion in the search results. For content to be indexed in Google Scholar, it must meet certain specified criteria. An earlier statistical estimate published in PLOS One using a mark and recapture method estimated approximately 80–90% coverage of all articles published in English with an estimate of 100 million.''Trend Watch'' (2014) Nature 509(7501), 405 – discussing Madian Khabsa and C Lee Giles (2014''The Number of Scholarly Documents on the Public W ...
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Indian Immunologicals Limited
Indian Immunologicals Limited or IIL is a subsidiary of National Dairy Development Board. It is based in Hyderabad, Telangana, India. IIL is registered in India as a Public Limited Company under the Companies Act, 1956 (Ministry Of Corporate Affairs - MCA Services), It was established in 1982 by the National Dairy Development Board. It is noted for developing veterinary and human vaccines for foot-and-mouth disease, rabies, bacterial vaccines, canine vaccines, hepatitis, measles, MMR and DPT. IIL is a major supplier of DPT, TT and Hepatitis B vaccines to India's large Universal Immunization Programme. IIL has three vaccine manufacturing facilities in India. The Gachibowli-Hyderabad facility is engaged in the production of vaccines, while the Karakapatla-Hyderabad facility produces animal health formulations and human vaccines. IIL's facility in Ooty exclusively produces human anti-rabies vaccine, “Abhayrab”. Pristine Biologicals Ltd is IIL's subsidiary in New Zealand and ...
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Patent Cooperation Treaty
The Patent Cooperation Treaty (PCT) is an international patent law treaty, concluded in 1970. It provides a unified procedure for filing patent applications to protect inventions in each of its contracting states. A patent application filed under the PCT is called an international application, or PCT application. A single filing of a PCT application is made with a Receiving Office (RO) in one language. It then results in a search performed by an International Searching Authority (ISA), accompanied by a written opinion regarding the patentability of the invention, which is the subject of the application. It is optionally followed by a preliminary examination, performed by an International Preliminary Examining Authority (IPEA). Finally, the relevant national or regional authorities administer matters related to the examination of application (if provided by national law) and issuance of patent. A PCT application does not itself result in the grant of a patent, since there is ...
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Japanese Encephalitis
Japanese encephalitis (JE) is an infection of the brain caused by the Japanese encephalitis virus (JEV). While most infections result in little or no symptoms, occasional inflammation of the brain occurs. In these cases, symptoms may include headache, vomiting, fever, confusion and seizures. This occurs about 5 to 15 days after infection. JEV is generally spread by mosquitoes, specifically those of the '' Culex'' type. Pigs and wild birds serve as a reservoir for the virus. The disease occurs mostly outside of cities. Diagnosis is based on blood or cerebrospinal fluid testing. Prevention is generally with the Japanese encephalitis vaccine, which is both safe and effective. Other measures include avoiding mosquito bites. Once infected, there is no specific treatment, with care being supportive. This is generally carried out in a hospital. Permanent problems occur in up to half of people who recover from JE. The disease primarily occurs in East and Southeast Asia as wel ...
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Hepatitis B
Hepatitis B is an infectious disease caused by the '' Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. For others, symptoms may appear 30 to 180 days after becoming infected and can include a rapid onset of sickness with nausea, vomiting, yellowish skin, fatigue, dark urine, and abdominal pain. Symptoms during acute infection typically last for a few weeks, though some people may feel sick for up to six months. Deaths resulting from acute stage HBV infections are rare. An HBV infection lasting longer than six months is usually considered chronic. The likelihood of developing chronic hepatitis B is higher for those who are infected with HBV at a younger age. About 90% of those infected during or shortly after birth develop chronic hepatitis B, while less than 10% of those infected after the age of five develop chronic cases. Most of those ...
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Rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, the result is virtually always death, regardless of treatment. The time period between contracting the disease and the start of symptoms is usually one to three months but can vary from less than one week to more than one year. The time depends on the distance the virus must travel along peripheral nerves to reach the central nervous system. Rabies is caused by lyssaviruses, including the rabies virus and Australian bat lyssavirus. It is spread when an infected animal bites or scratches a human or other animals. Saliva from an infected animal can also transmit rabies if the saliva ...
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Transcription Factors
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. Groups of TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are up to 1600 TFs in the human genome. Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of ...
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Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitute 1% of all described fungal species. Yeasts are unicellular organisms that evolved from multicellular ancestors, with some species having the ability to develop multicellular characteristics by forming strings of connected budding cells known as pseudohyphae or false hyphae. Yeast sizes vary greatly, depending on species and environment, typically measuring 3–4 µm in diameter, although some yeasts can grow to 40 µm in size. Most yeasts reproduce asexually by mitosis, and many do so by the asymmetric division process known as budding. With their single-celled growth habit, yeasts can be contrasted with molds, which grow hyphae. Fungal species that can take both forms (depending on temperature or other conditions) are ...
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