Otto Loewi
Otto Loewi (; 3 June 1873 – 25 December 1961) was a Germany, German-born pharmacology, pharmacologist and psychobiologist who discovered the role of acetylcholine as an endogenous neurotransmitter. For this discovery, he was awarded the Nobel Prize in Physiology or Medicine in 1936, which he shared with Sir Henry Hallett Dale, Henry Dale, who was a lifelong friend that helped to inspire the neurotransmitter experiment. Loewi met Dale in 1902 when spending some months in Ernest Starling's laboratory at University College, London. Biography Loewi was born in Frankfurt, Germany on June 3, 1873 in a Jews, Jewish family. He went to study medicine at the University of Strasbourg, Germany (now part of France) in 1891, where he attended courses by famous professors Gustav Albert Schwalbe, Gustav Schwalbe, Oswald Schmiedeberg, and Bernhard Naunyn among others. He received his medical doctoral degree in 1896. He also was a member of the fraternity Burschenschaft Germania Strassburg. S ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Otto Lowy
Otto Lowy (1921 – May 29, 2002) was the host of CBC Radio 2's ''The Transcontinental'' for 22 years until his death. The program was introduced each week as a "musical train ride through Europe". Lowy was born in Prague, Czechoslovakia, to an assimilated Jewish family and was the only member of his immediate family to survive World War II as he fled the country three days before Germany invaded. In England he worked as a member of the ground crew for the Czech Air Force squadron of the RAF. In 1948, he settled in Vancouver, British Columbia, and began his career with CBC Radio CBC Radio is the English-language radio operations of the Canadian Broadcasting Corporation. The CBC operates a number of radio networks serving different audiences and programming niches, all of which (regardless of language) are outlined below ..., initially as an actor in the series '' Adventures in Europe''. He went on to write radio plays, make documentaries as well as act in dramas and comedies. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neurotransmitter
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a Chemical synapse, synapse. The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. Some neurotransmitters are also stored in large dense core vesicles. The neurotransmitter's effect on the target cell is determined by the receptor it binds to. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available and often require a small number of biosynthetic steps for conversion. Neurotransmitters are essential to the function of complex neural systems. The exact number of unique neurotransmitters in humans is unknown, but more than 100 have been identified. Common neurotransmitters include Glutamate (neurotransmi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pneumonia
Pneumonia is an Inflammation, inflammatory condition of the lung primarily affecting the small air sacs known as Pulmonary alveolus, alveoli. Symptoms typically include some combination of Cough#Classification, productive or dry cough, chest pain, fever, and Shortness of breath, difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult. Diagnosis is often based on symptoms and physical examination. Chest X-rays, blood tests, and Microbiological culture, culture of the sputum may help confirm the diagnosis. The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. Risk factors for pneumonia include cystic fibrosis, chronic obstructive pulmonary disease (COPD), sickle cell disease, asthma, diabetes, heart failure, a history of smoking, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tuberculosis
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as inactive or latent tuberculosis. A small proportion of latent infections progress to active disease that, if left untreated, can be fatal. Typical symptoms of active TB are chronic cough with hemoptysis, blood-containing sputum, mucus, fever, night sweats, and weight loss. Infection of other organs can cause a wide range of symptoms. Tuberculosis is Human-to-human transmission, spread from one person to the next Airborne disease, through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with latent TB do not spread the disease. A latent infection is more likely to become active in those with weakened I ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Strasbourg
Strasbourg ( , ; ; ) is the Prefectures in France, prefecture and largest city of the Grand Est Regions of France, region of Geography of France, eastern France, in the historic region of Alsace. It is the prefecture of the Bas-Rhin Departments of France, department and the Seat of the European Parliament in Strasbourg, official seat of the European Parliament. The city has about three hundred thousand inhabitants, and together Eurométropole de Strasbourg, Greater Strasbourg and the arrondissement of Strasbourg have over five hundred thousand. Strasbourg's functional area (France), metropolitan area had a population of 860,744 in 2020, making it the eighth-largest metro area in France and home to 14% of the Grand Est region's inhabitants. The transnational Eurodistrict Strasbourg-Ortenau Eurodistrict, Strasbourg-Ortenau had a population of roughly 1,000,000 in 2022. Strasbourg is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Franz Hofmeister
Franz Hofmeister (30 August 1850, in Prague – 26 July 1922, in Würzburg) was an early protein scientist, and is famous for his studies of salts that influence the solubility and conformational stability of proteins. In 1902, Hofmeister became the first to propose that polypeptides were amino acids linked by peptide bonds, although this model of protein primary structure was independently and simultaneously conceived by Emil Fischer. Early life Hofmeister's father was a doctor in Prague, where Hofmeister first began his studies, under the physiologist Karl Hugo Huppert, himself a student of Carl Lehmann. Hofmeister's ''Habilitationsschrift'' in 1879 concerned the peptic products of digestion. Hofmeister became a Professor of Pharmacology at the First Faculty of Medicine, Charles University in Prague in 1885, then eventually moved to Strasbourg in 1896. The Hofmeister series Hofmeister discovered a series of salts that have consistent effects on the solubility of proteins ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Goethe University Of Frankfurt
Goethe University Frankfurt () is a public research university located in Frankfurt am Main, Germany. It was founded in 1914 as a citizens' university, which means it was founded and funded by the wealthy and active liberal citizenry of Frankfurt. The original name in German was Universität Frankfurt am Main (University of Frankfurt am Main). In 1932, the university's name was extended in honour of one of the most famous native sons of Frankfurt, the poet, philosopher and writer/dramatist Johann Wolfgang von Goethe. The university currently has around 48,000 students, distributed across four major campuses within the city. The university celebrated its 100th anniversary in 2014. The first female president of the university, Birgitta Wolff, was sworn into office in 2015, and was succeeded by Enrico Schleiff in 2021. 20 Nobel Prize winners have been affiliated with the university, including Max von Laue and Max Born. The university is also affiliated with 18 winners of the Gottfr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Martin Freund
Martin Freund (August 13, 1863 in Nysa, Kingdom of Prussia – March 13, 1920 in Frankfurt am Main) was a German chemist and professor at the Goethe-Universität Frankfurt am Main. Life Freund was born the son of a Jewish merchant. After graduating from the Realgymnasium at the Zwinger in Breslau, he started to study chemistry at the University of Breslau and the Humboldt University of Berlin in 1881. He received his doctorate in 1884. (contribution to the knowledge of malonic acid). During his studies he became a member of the ''Akademischer Naturwissenschaftlicher Verein zu Breslau'' in 1881. He was assistant to Hermann Wichelhaus and lecture assistant to August Wilhelm von Hofmann. In 1888 he habilitated in Berlin and in 1895 joined the Physikalischer Verein in Frankfurt am Main as a lecturer, where he headed its chemical laboratory. From 1905 he was a lecturer at the Akademie für Sozial- und Handelswissenschaften (Academy for Social and Commercial Sciences). In 1914 he ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bernhard Naunyn
Bernhard Naunyn (2 September 1839 – 26 July 1925) was a German pathologist, born in Berlin. Biography After receiving his degree at the University of Berlin in 1863, he became an assistant to pathologist Friedrich Theodor von Frerichs (1819–1885) at the Charité. Afterwards he was the head of medical clinics in Dorpat (1869–1871), Bern (1871–1872), Königsberg (1872–1888), and Strasbourg, where he also taught at the University of Strasbourg, Imperial University (1888–1904). Naunyn is remembered for his work in experimental pathology, particularly metabolic pathology; also referred to as xenobiotic metabolism. It was during the time he spent working at Frerich's clinic in Berlin that he became interested in the metabolic pathology regarding the liver, pancreas and other internal organs. In his studies of the fermentation processes of the stomach, he noticed the "contra-fermentation" properties of benzene. He discovered that the human organism excreted phenol after it ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oswald Schmiedeberg
Johann Ernst Oswald Schmiedeberg (10 October 1838 – 12 July 1921) was a Baltic German pharmacologist. In 1866 he earned his medical doctorate from the University of Dorpat with a thesis concerning the measurement of chloroform in blood, before becoming the first professor of pharmacology at the University of Strasbourg, where he remained for 46 years. In 1911, he testified in the '' United States v. Forty Barrels and Twenty Kegs of Coca-Cola'' trial, and later, was a major factor in the success of the German pharmaceutical industry prior to the Second World War, having trained most of the European professors at the time. Early life and family Oswald Schmiedeberg was born in Courland, one of the Baltic provinces of Russia. His father Wilhelm Ludwig (1809–1878) was a bailiff in Leidzen and later forester in Paggar (Estonia). His mother Anna Lucie Bernard (1813–1871) was the daughter of a watchmaker from Lausanne. Oswald was the eldest of six siblings of whom a brother Johann ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gustav Albert Schwalbe
Gustav Albert Schwalbe, M.D. (1 August 1844 – 23 April 1916) was a German anatomist and anthropologist from Quedlinburg. He was educated at the universities of Humboldt University of Berlin, Berlin, University of Zurich, Zurich, and University of Bonn, Bonn (Doctor of Medicine, M.D. 1866), he became in 1870 privat-docent at the University of Halle, in 1871 privatdozent and prosector at the University of Freiburg in Baden, in 1872 assistant professor at the University of Leipzig, and then professor of anatomy successively at the universities of University of Jena, Jena (1873), University of Königsberg, Königsberg (1881), and University of Strasbourg, Strassburg (1883) — at that time a German university, Alsace having been annexed to Germany. There he died. Known for his anthropological research of primitive man, Schwalbe considered the Neanderthal to be a direct ancestor of modern humans. Much to the dismay of the Dutch paleontologist Eugène Dubois (1858–1940) who ha ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jews
Jews (, , ), or the Jewish people, are an ethnoreligious group and nation, originating from the Israelites of History of ancient Israel and Judah, ancient Israel and Judah. They also traditionally adhere to Judaism. Jewish ethnicity, religion, and community are highly interrelated, as Judaism is their ethnic religion, though it is not practiced by all ethnic Jews. Despite this, religious Jews regard Gerim, converts to Judaism as members of the Jewish nation, pursuant to the Conversion to Judaism, long-standing conversion process. The Israelites emerged from the pre-existing Canaanite peoples to establish Kingdom of Israel (Samaria), Israel and Kingdom of Judah, Judah in the Southern Levant during the Iron Age.John Day (Old Testament scholar), John Day (2005), ''In Search of Pre-Exilic Israel'', Bloomsbury Publishing, pp. 47.5 [48] 'In this sense, the emergence of ancient Israel is viewed not as the cause of the demise of Canaanite culture but as its upshot'. Originally, J ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |