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Osteoma
An osteoma (plural ''osteomas'' or less commonly ''osteomata'') is a new piece of bone usually growing as a benign tumour on another piece of bone, typically the skull. When grown on other bone it is known as "homoplastic osteoma"; on other tissue it is called "heteroplastic osteoma". Osteoma represents the most common benign neoplasm of the nose and paranasal sinuses. The cause of osteomas is uncertain, but commonly accepted theories propose embryologic, traumatic, or infectious causes. They are present in Gardner's syndrome. Larger craniofacial osteomas may cause facial pain, headache, and infection due to obstructed nasofrontal ducts. Often, craniofacial osteoma presents itself through ocular signs and symptoms (such as proptosis). Variants * Osteoma cutis (also known as "Albright's hereditary osteodystrophy") * Osteoid osteoma * Fibro-osteoma * Chondro-osteoma File:Osteom der Stirnhoehle Roentgen.jpg, Osteoma of the frontal sinus seen on x-ray File:Osteom der Stirnho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteoid Osteoma
An osteoid osteoma is a benign (non-cancerous) bone tumor that arises from osteoblasts and some components of osteoclasts. It was originally thought to be a smaller version of an osteoblastoma. Osteoid osteomas tend to be less than 1.5 cm in size. The tumor can be in any bone in the body but are most common in long bones, such as the femur and tibia. They account for 10 to 12 percent of all benign bone tumors and 2 to 3 percent of all abnormal bone growths. Osteoid osteomas may occur at any age, and are most common in patients between the ages of 4 and 25 years old. Males are affected approximately three times more commonly than females. Osteoid osteomas are different than osteomas, which are rather found in older patients and localized in the skull. Signs and symptoms Common symptoms of an osteoid osteoma are: * dull or sharp pain that worsens at night * pain that is usually relieved by aspirin or other anti-inflammatory drugs * limping * painful scoliosis and muscle spa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteoma Cutis
Osteoma cutis is a cutaneous condition characterized by the presence of bone within the skin in the absence of a preexisting or associated lesion. Osteoma cutis often manifests as solid, varying-sized, skin-colored subcutaneous nodules. Signs and symptoms Osteoma cutis can present clinically as a single, asymptomatic lesion or as many lesions, depending on the circumstances. Their sizes vary from 0.1 to 5.0 cm. These lesions might show up as miliary lesions, papules, plaques, or nodules. They feel firm to the touch and might occasionally be the cause of yellowish or white spots on the skin. Bony spicules may occasionally be released from an ulcerated layer of skin above the epidermis. Causes There are two types of osteoma cutis: primary and secondary. When an osteoma cutis does not have an underlying lesion, it is categorized as primary. Primary osteoma cutis can arise alone or in combination with metabolic syndrome. When osteoma cutis is linked to neoplasia, dysembryoplasia, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Familial Adenomatous Polyposis
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated. Three variants are known to exist, FAP and attenuated FAP (originally called hereditary flat adenoma syndrome) are caused by ''APC'' gene defects on chromosome 5 while autosomal recessive FAP (or MUTYH-associated polyposis) is caused by defects in the '' MUTYH'' gene on chromosome 1. Of the three, FAP itself is the most severe and most common; although for all three, the resulting colonic polyps and cancers are initially confined to the colon wall. Detection and removal before metastasis outside the colon can greatly reduce and in many cases eliminate the spread of cancer. The root cause of FAP is understood to be a genetic mutation—a change in the body's tumour suppressor genes that prev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone
A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple functions. Bone tissue (osseous tissue), which is also called bone in the uncountable sense of that word, is hard tissue, a type of specialised connective tissue. It has a honeycomb-like matrix internally, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralisation of bone; osteoclasts are involved in the resorption of bone tissue. Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gardner Syndrome
Gardner's syndrome (also known as Gardner syndrome, familial polyposis of the colon, or familial colorectal polyposis) is a subtype of familial adenomatous polyposis (FAP). Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. The extracolonic tumors may include osteomas of the skull, thyroid cancer, epidermoid cysts, fibromas, as well as the occurrence of desmoid tumors in approximately 15% of affected individuals. Desmoid tumors are fibrous tumors that usually occur in the tissue covering the intestines and may be provoked by surgery to remove the colon. The countless polyps in the colon predispose to the development of colon cancer; if the colon is not removed, the chance of colon cancer is considered to be very significant. Polyps may also grow in the stomach, duodenum, spleen, kidneys, liver, mesentery, and small bowel. In a small number of cases, polyps have also a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteosclerosis
Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. It can manifest in localized or generalized osteosclerosis. Localized osteosclerosis can be caused by Legg–Calvé–Perthes disease, sickle-cell disease and osteoarthritis among others. Osteosclerosis can be classified in accordance with the causative factor into acquired and hereditary. Types Acquired osteosclerosis * Osteogenic bone metastasis caused by carcinoma of prostate and breast * Paget's disease of bone * Myelofibrosis (primary disorder or secondary to intoxication or malignancy) * Osteosclerosing types of chronic osteomyelitis * Hypervitaminosis D * Hyperparathyroidism * Schnitzler syndrome * Mastocytosis * Skeletal fluorosis * Monoclonal IgM Kappa cryoglobulinemia * Hepatitis C. Here ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ear Canal
The ear canal (external acoustic meatus, external auditory meatus, EAM) is a pathway running from the outer ear to the middle ear. The adult human ear canal extends from the auricle to the eardrum and is about in length and in diameter. Structure The human ear canal is divided into two parts. The elastic cartilage part forms the outer third of the canal; its anterior and lower wall are cartilaginous, whereas its superior and back wall are fibrous. The cartilage is the continuation of the cartilage framework of auricle. The cartilaginous portion of the ear canal contains small hairs and specialized sweat glands, called apocrine glands, which produce cerumen ( ear wax). The bony part forms the inner two thirds. The bony part is much shorter in children and is only a ring (''annulus tympanicus'') in the newborn. The layer of epithelium encompassing the bony portion of the ear canal is much thinner and therefore, more sensitive in comparison to the cartilaginous portion. Size ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Journal Of Pediatric Otorhinolaryngology
The ''International Journal of Pediatric Otorhinolaryngology'' is a peer-reviewed medical journal covering pediatrics and otorhinolaryngology. It was established in 1979 and is published 15 times per year by Elsevier. The founding and current editor-in-chief is Robert J. Ruben (Albert Einstein College of Medicine). According to the ''Journal Citation Reports'', the journal has a 2023 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 3.2 . References External links * Elsevier academic journals Otorhinolaryngology journals Pediatrics journals Academic journals established in 1979 English-language journals Journals published between 13 and 25 times per year {{otorhinolaryngology-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proptosis
Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. Exophthalmos has endocrine causes. In the case of Graves' disease, the displacement of the eye results from abnormal connective tissue deposition in the orbit and extraocular muscles, which can be visualized by CT or MRI. If left untreated, exophthalmos can cause the eyelids to fail to close during sleep, leading to corneal dryness and damage. Another possible complication is a form of redness or irritation called superior limbic keratoconjunctivitis, in which the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the disp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paranasal Sinuses
Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphenoidal sinuses are behind the eyes. The sinuses are named for the facial bones and sphenoid bone in which they are located. Their role is disputed. Structure Humans possess four pairs of paranasal sinuses, divided into subgroups that are named according to the bones within which the sinuses lie. They are all innervated by branches of the trigeminal nerve (CN V). * The maxillary sinuses, the largest of the paranasal sinuses, are under the eyes, in the maxillary bones (open in the back of the semilunar hiatus of the nose). They are innervated by the maxillary nerve (CN V2). * The frontal sinuses, superior to the eyes, in the frontal bone, which forms the hard part of the forehead. They are innervated by the ophthalmic nerve (CN V1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
