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Orally Dissolving Tablet
An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of Over-the-counter drug, over-the-counter (OTC) and Prescription drug, prescription medications. ODTs differ from traditional Tablet (pharmacy), tablets in that they are designed to be dissolved on the tongue rather than swallowed whole. The ODT serves as an alternative dosage form for patients who experience dysphagia (difficulty in swallowing) or for where compliance is a known issue and therefore an easier dosage form to take ensures that medication is taken. Common among all age groups, dysphagia is observed in about 35% of the general population, as well as up to 60% of the elderly institutionalized population and 18-22% of all patients in long-term care facilities ODTs may have a faster onset of effect than tablets or capsules, and have the convenience of a tablet that can be taken without water. During the last decade, ODTs have become available in a vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clonazepam
Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia. It is a long-acting tranquilizer of the benzodiazepine class. It possesses anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties. It is typically taken orally (swallowed by mouth) but is also used intravenously. Effects begin within one hour and last between eight and twelve hours in adults. Common side effects may include sleepiness, weakness, poor coordination, difficulty concentrating, and agitation. Clonazepam may also decrease memory formation. Long-term use may result in tolerance, dependence, and life-threatening withdrawal symptoms if stopped abruptly. Dependence occurs in one-third of people who take benzodiazepines for longer than four weeks. The risk of suicide increases, p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bristol-Myers Squibb
The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the ''Fortune'' 500 list of the largest U.S. corporations. For fiscal 2022, it had a total revenue of $46.2 billion. Bristol Myers Squibb manufactures prescription pharmaceuticals and biologics in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis, and psychiatric disorders. BMS's primary research and development (R&D) sites are located in Lawrence, New Jersey (formerly Squibb, near Princeton), Summit, New Jersey, formerly HQ of Celgene, New Brunswick, New Jersey; Redwood City, California; and Seville in Spain, with other sites in Devens and Cambridge, Massachusetts; Braine-l'Alleud, Belgium; Tokyo, Japan; Hyderabad; Bangalore, India and Wirr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Otsuka America
(), abbreviated OPC, is a pharmaceutical company headquartered in Tokyo, Osaka and Naruto, Japan. The company was established August 10, 1964. History OPC's parent company Otsuka Holdings Co. Ltd. joined the Tokyo Stock Exchange through an initial public offering (IPO) on December 15, 2010, at which time Otsuka Holdings was Japan's No.2 drug maker by sales after industry leader Takeda Pharmaceutical Company. The IPO debuted at $2.4 billion, making it the largest for a pharmaceutical company up to that time. Otsuka Pharmaceutical Co. Ltd Holdings In 1955, the company started a football club called "Otsuka Pharmaceutical SC." In 2005 the name changed to Tokushima Vortis. The club is based in Naruto. In 2008, Otsuka Pharmaceutical Co. acquired 49% of Alma S.A., which is the parent company of CG Roxane. In early 2012, Otsuka announced it would focus its "future operations on CNS disorders and oncology". This decision necessitated a revision in the terms of an agreement with UCB ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blister Pack
A blister pack is any of several types of pre-formed plastic packaging used for small consumer goods, foods, and for pharmaceuticals. The primary component of a blister pack is a cavity or pocket made from a formable web, usually a thermoformed plastic. This usually has a backing of paperboard or a lidding seal of aluminum foil or plastic. A blister that folds onto itself is often called a clamshell. Blister packs are useful for protecting products against external factors, such as humidity and contamination for extended periods of time. Opaque blisters also protect light-sensitive products against UV rays. Uses Blister packs are used to package products such as toys, hardware, medication, etc. Many blister packaging machines use heat and pressure via a die to form the cavity or pocket from a roll or sheet of plastic. In recent years, improvements in cold forming—specifically allowing steeper depth/angles during forming, which minimizes the amount of material used for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diluent
A diluent (also referred to as a filler, dilutant or thinner) is a diluting agent. Certain fluids are too viscous to be pumped easily or too dense to flow from one particular point to the other. This can be troublesome, because it might not be economically feasible to transport such fluids in this state. To ease this restricted movement, diluents are added. This decreases the viscosity of the fluids, thereby also decreasing the pumping/transportation costs. One industrial application is the transport of crude oil via pipelines. Heavy crude oil/bitumen are fluids with high viscosity, especially at low temperatures. The addition of a diluent enables the diluted fluid ( dilbit in the case of bitumen) to meet pipeline specifications in order for it to be efficiently transported. Typical diluent in this case is naphtha or condensate. Types of diluents more familiar to the general public include paint thinner and nail polish thinner, both of which improve the consistency and app ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cellulose
Cellulose is an organic compound with the chemical formula, formula , a polysaccharide consisting of a linear chain of several hundred to many thousands of glycosidic bond, β(1→4) linked glucose, D-glucose units. Cellulose is an important structural component of the primary cell wall of green plants, many forms of algae and the oomycetes. Some species of bacteria secrete it to form biofilms. Cellulose is the most abundant biopolymer, organic polymer on Earth. The cellulose content of cotton fibre is 90%, that of wood is 40–50%, and that of dried hemp is approximately 57%. Cellulose is mainly used to produce paperboard and paper. Smaller quantities are converted into a wide variety of derivative products such as cellophane and rayon. Conversion of cellulose from energy crops into biofuels such as cellulosic ethanol is under development as a renewable fuel source. Cellulose for industrial use is mainly obtained from wood pulp and cotton. Cellulose is also greatly affected by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouth Feel
Mouthfeel refers to the physical sensations in the mouth caused by food or drink, making it distinct from taste. It is a fundamental sensory attribute which, along with taste and smell, determines the overall flavor of a food item. Mouthfeel is also sometimes referred to as texture. It is used in many areas related to the testing and evaluating of foodstuffs, such as wine-tasting and food rheology. It is evaluated from initial perception on the palate to first bite, through chewing to swallowing and aftertaste. In wine-tasting, for example, mouthfeel is usually used with a modifier (big, sweet, tannic, chewy, etc.) to the general sensation of the wine in the mouth. Research indicates texture and mouthfeel can also influence satiety with the effect of viscosity most significant. Mouthfeel is often related to a product's water activity—hard or crisp products having lower water activities and soft products having intermediate to high water activities. Qualities perceived ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnesium Stearate
Magnesium stearate is the chemical compound with the formula . It is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+). Magnesium stearate is a white, water-insoluble powder. Its applications exploit its softness, insolubility in many solvents, and low toxicity. It is used as a release agent and as a component or lubricant in the production of pharmaceuticals and cosmetics.Angelo Nora, Alfred Szczepanek, Gunther Koenen, "Metallic Soaps" in Ullmann's Encyclopedia of Industrial Chemistry 2005 Wiley-VCH, Weinheim. Manufacturing Magnesium stearate is produced by the reaction of sodium stearate with magnesium salts or by treating magnesium oxide with stearic acid. Uses Magnesium stearate is often used in food preparations as a anti-adherent and anticaking agent. in the manufacture of medical tablets, capsules and powders. In this regard, the substance is also useful because it has lubricating properties, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Die (manufacturing)
A die is a specialized machine tool used in manufacturing industries to cut and/or Forming (metalworking), form material to a desired shape or profile. ''Stamping (metalworking), Stamping dies'' are used with a machine press, press, as opposed to ''Draw plate, drawing dies'' (used in the manufacture of wire) and ''Die casting, casting dies'' (used in Molding (process), molding) which are not. Like molds, dies are generally customized to the item they are used to create. Products made with dies range from simple paper clips to complex pieces used in advanced technology. Continuous production, Continuous-feed laser cutting may displace the analogous die-based process in the automotive industry, among others. Die stamping Blanking and piercing are two Shearing (manufacturing), die cutting operations, and Bending (metalworking), bending is an example of a die forming operation. Die forming Forming operations work by deforming materials like sheet metal or plastic using force (Compre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kilonewton
The newton (symbol: N) is the unit of force in the International System of Units (SI). Expressed in terms of SI base units, it is 1 kg⋅m/s2, the force that accelerates a mass of one kilogram at one metre per second squared. The unit is named after Isaac Newton in recognition of his work on classical mechanics, specifically his second law of motion. Definition A newton is defined as 1 kg⋅m/s2 (it is a named derived unit defined in terms of the SI base units). One newton is, therefore, the force needed to accelerate one kilogram of mass at the rate of one metre per second squared in the direction of the applied force. The units "metre per second squared" can be understood as measuring a rate of change in velocity per unit of time, i.e. an increase in velocity by one metre per second every second. In 1946, the General Conference on Weights and Measures (CGPM) Resolution 2 standardized the unit of force in the MKS system of units to be the amount needed t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
