Onychogryphosis
Onychogryphosis is a hypertrophy that may produce nails resembling claws or a ram's horn. Causes Onychogryphosis may be caused by trauma or peripheral vascular disease, but most often secondary to self-neglect and failure to cut the nails for extended periods of time.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . This condition is most commonly seen in the elderly. Treatment Some recommend avulsion of the nail plate with surgical destruction of the nail matrix with phenol or the carbon dioxide laser, if the blood supply is adequate.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. . Epidemiology Severe congenital onychogryphosis affecting all twenty nailbeds has been recorded in two families who exhibit the dominant allele for a certain gene. Congenital onychogryphosis of the fifth toe (the baby, little, pinky or small toe) is fairl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Onychogryphosis (2)
Onychogryphosis is a hypertrophy that may produce Nail (anatomy), nails resembling claws or a ram's horn. Causes Onychogryphosis may be caused by trauma or peripheral vascular disease, but most often secondary to self-neglect and failure to Nail cutter, cut the nails for extended periods of time.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . This condition is most commonly seen in the Old age, elderly. Treatment Some recommend surgical treatment of ingrown toenails#Avulsion procedure, avulsion of the nail plate with surgical destruction of the nail matrix with phenol or the carbon dioxide laser, if the blood supply is adequate.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. . Epidemiology Severe congenital onychogryphosis affecting all twenty nailbeds has been recorded in two families who exhibit the dominant allele for a certain gene. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis (skin), epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. Embryology, In the embryo, the epidermis, hair, and glands form from the ectod ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nail Matrix
A nail is a protective plate characteristically found at the tip of the digits (fingers and toes) of all primates, corresponding to the claws in other tetrapod animals. Fingernails and toenails are made of a tough rigid protein called alpha-keratin, a polymer also found in the claws, hooves, and horns of vertebrates. Structure The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. Parts of the nail The nail matrix is the active tissue (or germinal matrix) that generates cells. The cells harden as they move outward from the nail root to the nail plate. The nail matrix is also known as the ''matrix unguis'', keratogenous membrane, or onychostroma. It is the part of the nail bed that is beneath the nail and contains nerves, lymph, and blood vessels. The matrix produces cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nailbeds
A nail is a protective plate characteristically found at the tip of the digits (fingers and toes) of all primates, corresponding to the claws in other tetrapod animals. Fingernails and toenails are made of a tough rigid protein called alpha-keratin, a polymer also found in the claws, hooves, and horns of vertebrates. Structure The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. Parts of the nail The nail matrix is the active tissue (or germinal matrix) that generates cells. The cells harden as they move outward from the nail root to the nail plate. The nail matrix is also known as the ''matrix unguis'', keratogenous membrane, or onychostroma. It is the part of the nail bed that is beneath the nail and contains nerves, lymph, and blood vessels. The matrix produces cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nail (anatomy)
A nail is a protective plate characteristically found at the tip of the digit (anatomy), digits (fingers and toes) of all primates, corresponding to the claws in other tetrapod animals. Fingernails and toenails are made of a tough rigid protein called alpha-keratin, a polymer also found in the claws, hooves, and horn (anatomy), horns of vertebrates. Structure The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. Parts of the nail The nail matrix is the active Tissue (biology), tissue (or Germ layer, germinal Matrix (biology), matrix) that generates cells. The cells harden as they move outward from the nail root to the nail plate. The nail matrix is also known as the ''matrix unguis'', keratogenous membrane, or onychostroma. It is the part of the nail bed that is beneath the nail and contains nerves, lymph, and blood vessels. The matrix produces cells that become the nail plate. The width and thickness of the nail p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Manicurists
A manicure is a mostly cosmetic beauty treatment for the fingernails and hands performed at home or in a nail salon. A manicure usually consists of filing and shaping the free edge of nails, pushing and clipping (with a cuticle pusher and cuticle nippers) any nonliving tissue at the cuticle and removing hangnails, treatments with various liquids, massage of the hand, and the application of fingernail polish. When the same is applied to the toenails and feet, the treatment is referred to as a pedicure. Together, the treatments may be known as a mani-pedi. Some manicures include painting pictures or designs on the nails, applying small decals, or imitation jewels (from 2 dimension to 3 dimension). Other nail treatments may include the application of artificial gel nails, tips, or acrylics, which may be referred to as ''French manicures''. Nail technicians, such as manicurists and pedicurists, must be licensed in certain states and countries, and must follow government ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fifth Toe
Toes are the digits of the foot of a tetrapod. Animal species such as cats that walk on their toes are described as being ''digitigrade''. Humans, and other animals that walk on the soles of their feet, are described as being ''plantigrade''; ''unguligrade'' animals are those that walk on hooves at the tips of their toes. Structure There are normally five toes present on each human foot. Each toe consists of three phalanx bones, the proximal, middle, and distal, with the exception of the big toe (). For a minority of people, the little toe also is missing a middle bone. The hallux only contains two phalanx bones, the proximal and distal. The joints between each phalanx are the interphalangeal joints. The proximal phalanx bone of each toe articulates with the metatarsal bone of the foot at the metatarsophalangeal joint. Each toe is surrounded by skin, and present on all five toes is a toenail. The toes are, from medial to lateral: * the first toe, also known as the hal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dominant Allele
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and the second is called recessive. This state of having two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes ( autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, there are other forms of dominance, such as incompl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Carbon Dioxide Laser
The carbon-dioxide laser (CO2 laser) was one of the earliest gas lasers to be developed. It was invented by C. Kumar N. Patel, Kumar Patel of Bell Labs in 1964 and is still one of the most useful types of laser. Carbon dioxide, Carbon-dioxide lasers are the highest-power continuous-wave lasers that are currently available. They are also quite efficient: the ratio of output power to Laser pumping, pump power can be as large as 20%. The CO2 laser produces a beam of infrared light with the principal wavelength bands centering on 9.6 and 10.6 Micrometre, micrometers (μm). Amplification The active laser medium (laser gain/Amplifier, amplification medium) is a gas discharge which is air- or water-cooled, depending on the power being applied. The filling gas within a sealed discharge tube consists of around 10–20% carbon dioxide (), around 10–20% nitrogen (), a few percent hydrogen () and/or xenon (Xe), with the remainder being helium (He). A different mixture is used in a ''fl ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phenol
Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile and can catch fire. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it requires careful handling because it can cause chemical burns. It is acutely toxic and is considered a health hazard. Phenol was first extracted from coal tar, but today is produced on a large scale (about 7 million tonnes a year) from petroleum-derived feedstocks. It is an important industrial commodity as a precursor to many materials and useful compounds, and is a liquid when manufactured. It is primarily used to synthesize plastics and related materials. Phenol and its chemical derivatives are essential for production of polycarbonates, epoxies, explosives such as picric acid, Bakelite, nylon, detergents, herbicides such as phenoxy herbicides, and numerous pharmaceuti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hypertrophy
Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells. It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number. Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally induced proliferation and enlargement of the cells of the uterus during pregnancy. Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel). Gallery Gould Pyle 234.jpg, Breasts Hypertrophied clitoris.jpg, Clitoris Head of a boy with hypertrophy of the ear Wellcome L0062496.j ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Surgical Treatment Of Ingrown Toenails
Surgical treatments of ingrown toenails include a number of different options. If conservative treatment of a minor ingrown toenail does not succeed or if the ingrown toenail is severe, surgical management by a podiatrist is recommended. The initial surgical approach is typically a partial avulsion of the nail plate known as a wedge resection or a complete removal of the toenail. If the ingrown toenail recurs despite this treatment, destruction of the germinal matrix with phenol is recommended. As an alternative, one may use 10% sodium hydroxide which is less toxic or trichloroacetic acid which may give faster healing time. Antibiotics are not needed if surgery is performed. Wedge resection The physician will perform an onychectomy in which the nail along the edge that is growing into the skin is cut away ( ablated) and the offending piece of nail is pulled out. Any infection is surgically drained. This process is referred to as a "wedge resection" or simple surgical ablati ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |