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Observational Interpretation Fallacy
The observational interpretation fallacy is the cognitive bias where associations identified in observational studies are misinterpreted as causal relationships. This misinterpretation often influences clinical guidelines, public health policies, and medical practices, sometimes to the detriment of patient safety and resource allocation. The term was introduced in a 2024 study published in the ''Journal of Evaluation in Clinical Practice''. Researchers highlighted multiple historical instances where conclusions drawn from observational data led to changes in medical practice, which were later refuted by randomized controlled trials (RCTs). The phenomenon emphasizes the challenges of distinguishing correlation from causation, particularly in the absence of robust experimental controls. The role of cognitive bias Researchers aiming to use observational data to infer causation must control for confounding variables, as failing to do so can lead to spurious correlations, which then ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Example Of Association And Causation
Example may refer to: * ''exempli gratia'' (e.g.), usually read out in English as "for example" * .example, reserved as a domain name that may not be installed as a top-level domain of the Internet ** example.com, example.net, example.org, and example.edu: second-level domain names reserved for use in documentation as examples * HMS Example (P165), HMS ''Example'' (P165), an Archer-class patrol and training vessel of the Royal Navy Arts * ''The Example'', a 1634 play by James Shirley * The Example (comics), ''The Example'' (comics), a 2009 graphic novel by Tom Taylor and Colin Wilson * Example (musician), the British dance musician Elliot John Gleave (born 1982) * Example (album), ''Example'' (album), a 1995 album by American rock band For Squirrels See also * Exemplar (other), a prototype or model which others can use to understand a topic better * Exemplum, medieval collections of short stories to be told in sermons * Eixample, a district of Barcelona with di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fallacies
A fallacy is the use of invalid or otherwise faulty reasoning in the construction of an argument that may appear to be well-reasoned if unnoticed. The term was introduced in the Western intellectual tradition by the Aristotelian '' De Sophisticis Elenchis''. Fallacies may be committed intentionally to manipulate or persuade by deception, unintentionally because of human limitations such as carelessness, cognitive or social biases and ignorance, or potentially due to the limitations of language and understanding of language. These delineations include not only the ignorance of the right reasoning standard but also the ignorance of relevant properties of the context. For instance, the soundness of legal arguments depends on the context in which they are made. Fallacies are commonly divided into "formal" and "informal". A formal fallacy is a flaw in the structure of a deductive argument that renders the argument invalid, while an informal fallacy originates in an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Randomized Controlled Trial
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures, diets or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing standard of care; these are then termed the 'expe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin
Vitamins are Organic compound, organic molecules (or a set of closely related molecules called vitamer, vitamers) that are essential to an organism in small quantities for proper metabolism, metabolic function. Nutrient#Essential nutrients, Essential nutrients cannot be biosynthesis, synthesized in the organism in sufficient quantities for survival, and therefore must be obtained through the Diet (nutrition), diet. For example, vitamin C can be synthesized by some species but not by others; it is not considered a vitamin in the first instance but is in the second. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. The term ''vitamin'' does not include the three other groups of essential nutrients: mineral (nutrient), minerals, essential fatty acids, and essential amino acids. Major health organizations list thirteen vitamins: * Vitamin A (all-' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antioxidant
Antioxidants are Chemical compound, compounds that inhibit Redox, oxidation, a chemical reaction that can produce Radical (chemistry), free radicals. Autoxidation leads to degradation of organic compounds, including living matter. Antioxidants are frequently added to industrial products, such as polymers, fuels, and lubricants, to extend their usable lifetimes. Foods are also treated with antioxidants to prevent Food spoilage, spoilage, in particular the rancidification of Vegetable oil, oils and fats. In Cell (biology), cells, antioxidants such as glutathione, mycothiol, or bacillithiol, and enzyme systems like superoxide dismutase, inhibit damage from oxidative stress. Known diet (nutrition), dietary antioxidants are vitamins vitamin A, A, vitamin C, C, and vitamin E, E, but the term has also been applied to various compounds that exhibit antioxidant properties in vitro, having little evidence for antioxidant properties in vivo. Dietary supplements marketed as antioxidants hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Women's Health Initiative
The Women's Health Initiative (WHI) was a series of clinical studies initiated by the U.S. National Institutes of Health (NIH) in 1991, to address major health issues causing morbidity and mortality in postmenopausal women. It consisted of three clinical trials (CT) and an observational study (OS). In particular, randomized controlled trials were designed and funded that addressed cardiovascular disease, cancer, and osteoporosis. In its entirety, the WHI enrolled more than 160,000 postmenopausal women aged 50–79 years (at time of study enrollment) over 15 years, making it one of the largest U.S. prevention studies of its kind, with a budget of $625 million. A 2014 analysis calculated a net economic return on investment of $37.1 billion for the estrogen-plus-progestin arm of the study's hormone trial alone, providing a strong case for the continued use of this variety of large, publicly funded population study. In the years following the WHI, studies have shown a decrease in bre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone Replacement Therapy
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. Effects of menopause can include symptoms such as hot flashes, accelerated skin aging, vaginal dryness, decreased muscle mass, and complications such as osteoporosis (bone loss), sexual dysfunction, and vaginal atrophy. They are mostly caused by low levels of female sex hormones (e.g. estrogens) that occur during menopause. Estrogens and progestogens are the main hormone drugs used in HRT. Progesterone is the main female sex hormone that occurs naturally and is also manufactured into a drug that is used in menopausal hormone therapy. Although both classes of hormones can have symptomatic benefit, progestogen is specifically added to estrogen regimens, unless the uterus has been removed, to avoid the increased risk of endometrial cancer. Unopposed estrogen therapy promotes end ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bendectin
Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride ( vitamin B6) and doxylamine succinate. It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals. Medical uses The combination of pyridoxine, commonly referred to as vitamin B6 and doxylamine may be effective for the management of nausea and vomiting of pregnancy, but it is only recommended for use in a small number of cases after lifestyle, diet and vitamin B6. A 2018 review found the benefit was small. Doxylamine and pyridoxine are pregnancy compatible drugs,Briggs GG, Freeman RK. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 10th edition. 2015. Published by: Wolters Kluwer Health. consistent with FDA's safety assessment of the combination product. They have been categorize ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cognitive Bias
A cognitive bias is a systematic pattern of deviation from norm (philosophy), norm or rationality in judgment. Individuals create their own "subjective reality" from their perception of the input. An individual's construction of reality, not the Objectivity (philosophy), objective input, may dictate their behavior in the world. Thus, cognitive biases may sometimes lead to perceptual distortion, inaccurate judgment, illogical interpretation, and irrationality. While cognitive biases may initially appear to be negative, some are adaptive. They may lead to more effective actions in a given context. Furthermore, allowing cognitive biases enables faster decisions which can be desirable when timeliness is more valuable than accuracy, as illustrated in Heuristic (psychology), heuristics. Other cognitive biases are a "by-product" of human processing limitations, resulting from a lack of appropriate mental mechanisms (bounded rationality), the impact of an individual's constitution and bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Confirmation Bias
Confirmation bias (also confirmatory bias, myside bias, or congeniality bias) is the tendency to search for, interpret, favor and recall information in a way that confirms or supports one's prior beliefs or Value (ethics and social sciences), values. People display this bias when they select information that supports their views, ignoring contrary information or when they interpret ambiguous evidence as supporting their existing attitudes. The effect is strongest for desired outcomes, for emotionally charged issues and for deeply entrenched beliefs. Biased search for information, biased interpretation of this information and biased memory recall, have been invoked to explain four specific effects: # ''attitude polarization'' (when a disagreement becomes more extreme even though the different parties are exposed to the same evidence) # ''belief perseverance'' (when beliefs persist after the evidence for them is shown to be false) # the ''irrational primacy effect'' (a greater relia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Post Hoc Ergo Propter Hoc
''Post hoc ergo propter hoc'' (Latin: 'after this, therefore because of this') is an informal fallacy that states "Since event Y ''followed'' event X, event Y must have been ''caused'' by event X." It is a fallacy in which an event is presumed to have been caused by a closely preceding event merely on the grounds of temporal succession. This type of reasoning is fallacious because mere temporal succession does not establish a causal connection. It is often shortened simply to ''post hoc fallacy''. A logical fallacy of the questionable cause variety, it is subtly different from the fallacy '' cum hoc ergo propter hoc'' ('with this, therefore because of this'), in which two events occur simultaneously or the chronological ordering is insignificant or unknown. Post hoc is a logical fallacy in which one event seems to be the cause of a later event because it occurred earlier. ''Post hoc'' is a particularly tempting error because correlation sometimes appears to suggest causality. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
