|
Obesity Paradox
The obesity paradox is the finding in some studies of a lower mortality rate for overweight or obese people within certain subpopulations. The paradox has been observed in people with cardiovascular disease and cancer. Explanations for the paradox range from excess weight being protective to the statistical association being caused by methodological flaws such as confounding, detection bias, reverse causality, or selection bias. Description The terminology "reverse epidemiology" was first proposed by Kamyar Kalantar-Zadeh in the journal '' Kidney International'' in 2003 and in the ''Journal of the American College of Cardiology'' in 2004. It is a contradiction to prevailing medical concepts of prevention of atherosclerosis and cardiovascular disease; however, active prophylactic treatment of heart disease in otherwise healthy, asymptomatic people has been and is controversial in the medical community for several years. The mechanism responsible for this reversed association is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiovascular Disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximately 13% of CVD deaths, while tobacco accounts for 9%, di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nursing Home
A nursing home is a facility for the residential care of older people, senior citizens, or disabled people. Nursing homes may also be referred to as care homes, skilled nursing facilities (SNF), or long-term care facilities. Often, these terms have slightly different meanings to indicate whether the institutions are public or private, and whether they provide mostly assisted living, or nursing care and emergency medical care. Nursing homes are used by people who do not need to be in a hospital, but require care that is hard to provide in a home setting. The nursing home staff attends to the patients' medical and other needs. Most nursing homes have nursing aides and skilled nurses on hand 24 hours a day. In the United States, while nearly 1 in 10 residents aged 75 to 84 stays in a nursing home for five or more years, nearly 3 in 10 residents in that age group stay less than 100 days, the maximum duration covered by Medicare, according to the American Association for Long-Term ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Waist To Hip Ratio
The waist is the part of the abdomen between the rib cage and hips. Normally, it is the narrowest part of the torso. ''Waistline'' refers to the horizontal line where the waist is narrowest, or to the general appearance of the waist. Structure Because of this and because the waist is often synonymous with the stomach, one can become confused as to the exact location of the waist. Another confusing factor is that the waistline differs on different people. A study showed that self-reported measurements, as opposed to measurement done by a technician, underestimated waist circumference and this underestimation increased with increased body size. In the study, waist circumference measured at the level of the umbilicus was larger than that measured at the natural waist. To locate the natural waistline, one need simply stand upright and then tilt over to the side, keeping the legs and hips straight. Where the torso creases is the natural waistline. Size Waist measurement Strict ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Waist Circumference
The waist is the part of the Human abdomen, abdomen between the rib cage and Hip (anatomy), hips. Normally, it is the narrowest part of the torso. ''Waistline'' refers to the horizontal line where the waist is narrowest, or to the general appearance of the waist. Structure Because of this and because the waist is often synonymous with the stomach, one can become confused as to the exact location of the waist. Another confusing factor is that the waistline differs on different people. A study showed that self-reported measurements, as opposed to measurement done by a technician, underestimated waist circumference and this underestimation increased with increased body size. In the study, waist circumference measured at the level of the Navel, umbilicus was larger than that measured at the natural waist. To locate the natural waistline, one need simply stand upright and then tilt over to the side, keeping the legs and hips straight. Where the torso creases is the natural waistli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Digital Object Identifier
A digital object identifier (DOI) is a persistent identifier or handle used to uniquely identify various objects, standardized by the International Organization for Standardization (ISO). DOIs are an implementation of the Handle System; they also fit within the URI system ( Uniform Resource Identifier). They are widely used to identify academic, professional, and government information, such as journal articles, research reports, data sets, and official publications. A DOI aims to resolve to its target, the information object to which the DOI refers. This is achieved by binding the DOI to metadata about the object, such as a URL where the object is located. Thus, by being actionable and interoperable, a DOI differs from ISBNs or ISRCs which are identifiers only. The DOI system uses the indecs Content Model to represent metadata. The DOI for a document remains fixed over the lifetime of the document, whereas its location and other metadata may change. Referring to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Effects Of Tobacco
Tobacco products, especially when smoked or used orally, have serious negative effects on human health. Smoking and smokeless tobacco use are the single greatest causes of preventable death globally. Half of tobacco users die from complications related to such use. Current smokers are estimated to die an average of 10 years earlier than non-smokers. The World Health Organization estimates that, in total, about 8 million people die from tobacco-related causes, including 1.3 million non-smokers due to secondhand smoke. It is further estimated to have caused 100 million deaths in the 20th century. Tobacco smoke contains over List of cigarette smoke carcinogens, 70 chemicals, known as carcinogens, that cause cancer. It also contains nicotine, a highly Addiction, addictive psychoactive drug. When tobacco is smoked, the nicotine causes Physical dependence, physical and psychological dependency. Cigarettes sold in least developed countries have higher tar content and are less likely to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Observational Study
In fields such as epidemiology, social sciences, psychology and statistics, an observational study draws inferences from a sample (statistics), sample to a statistical population, population where the dependent and independent variables, independent variable is not under the Scientific control, control of the researcher because of ethical concerns or logistical constraints. One common observational study is about the possible effect of a treatment on subjects, where the assignment of subjects into a treated group versus a control group is outside the control of the investigator. This is in contrast with experiments, such as randomized controlled trials, where each subject is Random assignment, randomly assigned to a treated group or a control group. Observational studies, for lacking an assignment mechanism, naturally present difficulties for inferential analysis. Motivation The independent variable may be beyond the control of the investigator for a variety of reasons: * A rand ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sampling Bias
In statistics, sampling bias is a bias (statistics), bias in which a sample is collected in such a way that some members of the intended statistical population, population have a lower or higher sampling probability than others. It results in a biased sample of a population (or non-human factors) in which all individuals, or instances, were not equally likely to have been selected. If this is not accounted for, results can be erroneously attributed to the phenomenon under study rather than to the method of sampling (statistics), sampling. Medical sources sometimes refer to sampling bias as ascertainment bias. Ascertainment bias has basically the same definition, but is still sometimes classified as a separate type of bias. Distinction from selection bias Sampling bias is usually classified as a subtype of selection bias, sometimes specifically termed sample selection bias, but some classify it as a separate type of bias. A distinction, albeit not universally accepted, of samplin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artifact (error)
In natural science and signal processing, an artifact or artefact is any error in the perception or representation of any information introduced by the involved equipment or technique(s). Statistics In ''statistics'', statistical artifacts are apparent effects that are introduced inadvertently by methods of data analysis rather than by the process being studied. Computer science In ''computer science'', digital artifacts are anomalies introduced into digital signals as a result of digital signal processing. Microscopy In ''microscopy'', visual artifacts are sometimes introduced during the processing of samples into slide form. Econometrics In ''econometrics'', which focuses on computing relationships between related variables, an artifact is a spurious finding, such as one based on either a faulty choice of variables or an over-extension of the computed relationship. Such an artifact may be called a ''statistical artifact''. For instance, imagine a hypothetical finding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insulin Resistance
Insulin resistance (IR) is a pathological response in which cells in insulin-sensitive tissues in the body fail to respond normally to the hormone insulin or downregulate insulin receptors in response to hyperinsulinemia. Insulin is a hormone that facilitates the transport of glucose from blood into cells, thereby reducing blood glucose (blood sugar). Insulin is released by the pancreas in response to carbohydrates consumed in the diet. In states of insulin resistance, the same amount of insulin does not have the same effect on glucose transport and blood sugar levels. There are many causes of insulin resistance and the underlying process is still not completely understood. Risk factors for insulin resistance include obesity, sedentary lifestyle, family history of diabetes, various health conditions, and certain medications. Insulin resistance is considered a component of the metabolic syndrome. Insulin resistance can be improved or reversed with lifestyle approaches, such a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypertension
Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide. High blood pressure is classified as essential hypertension, primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to non-specific lifestyle and Genetics, genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, overweight, excess body weight, smoking, physical inactivity and Alcohol (drug), alcohol use. The remaining 5–10% of cases are categorized as secondary hypertension, d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weight Loss
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can either occur unintentionally because of malnourishment or an underlying disease, or from a conscious effort to improve an actual or perceived overweight or obese state. "Unexplained" weight loss that is not caused by reduction in calorific intake or increase in exercise is called cachexia and may be a symptom of a serious medical condition. Intentional Intentional weight loss is the loss of total body mass as a result of efforts to improve physical fitness, fitness and health, or to change Human physical appearance, appearance through slimming. Weight loss is the main Management of obesity, treatment for obesity, and there is substantial evidence this can prevent progression from prediabetes to Diabetes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
