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Nurd (other)
Nurd or Nurds may refer to: * Mi-2/NuRD complex, in molecular biology * Nerd or nurd, a person * ''Nurds ''Nurds'' is the second studio album by the folk trio the Roches, released on Warner Bros. Records in 1980. It was positively reviewed although not quite as highly as their first album. The ''Rolling Stone'' review noted that they were "not just ...'', a 1980 album by the Roches See also * Nerd (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mi-2/NuRD Complex
In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities. , Mi-2/NuRD was the only known protein complex that couples chromatin remodeling ATPase and chromatin deacetylation enzymatic functions. The NuRD complex contains seven subunits: the histone deacetylase core proteins HDAC1 and HDAC2, the histone-binding proteins RbAp46 and RbAp48, the metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 (aka Mi-2alpha) or CHD4 (aka Mi-2beta). The histone deacetylases HDAC1 and HDAC2 and the histone binding proteins RbAp48 and RbAp46 form a core complex shared between NuRD and Sin3-histone deacetylase complexes. Overexpression of Mbd3, a subunit of NuRD, inhibits induction of iPSCs. Depletion of Mbd3, on the other hand, improves repr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerd
A nerd is a person seen as overly intellectual, obsessive, introverted or lacking social skills. Such a person may spend inordinate amounts of time on unpopular, little known, or non-mainstream activities, which are generally either highly technical, abstract, or relating to topics of science fiction or fantasy, to the exclusion of more mainstream activities. Additionally, many so-called nerds are described as being shy, quirky, pedantic, and unattractive. Originally derogatory, the term "nerd" was a stereotype, but as with other pejoratives, it has been reclaimed and redefined by some as a term of pride and group identity. Etymology The first documented appearance of the word ''nerd'' is as the name of a creature in Dr. Seuss's book ''If I Ran the Zoo'' (1950), in which the narrator Gerald McGrew claims that he would collect "a Nerkle, a Nerd, and a Seersucker too" for his imaginary zoo.American Heritage Dictionary of the English Language, Third Edition, p. 1212, Houghton M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nurds
''Nurds'' is the second studio album by the folk trio the Roches, released on Warner Bros. Records in 1980. It was positively reviewed although not quite as highly as their first album. The ''Rolling Stone'' review noted that they were "not just entertaining but downright terrifying". The album peaked at number 130 on the ''Billboard'' 200. Track listing Credits * Recordist: Jon Mathias * Assistant: Dave Alhard * Maggie Roche: acoustic guitar, vocals * Suzzy Roche: acoustic guitar, vocals * Terre Roche: acoustic guitar, electric guitar, vocals * Jay Dee Daugherty: drums * Fred Smith: electric bass guitar * Lincoln Goines: acoustic bass guitar * Jon Mathias: electric bass guitar on "Nurds" * Gabriel Katona: synthesizer * Bob Conti: percussion * Bobby Gordon: clarinet on "Bobby's Song" * Basic tracks and vocals recorded at Record Plant The Record Plant is a recording studio established in New York City in 1968 and currently operating in Los Angeles, California. Known for inn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |