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Norman Pirie
Norman Wingate Pirie FRS (1 July 1907 – 29 March 1997), was a British biochemist and virologist who, along with Frederick Bawden, discovered that a virus can be crystallized by isolating tomato bushy stunt virus in 1936. This was an important milestone in understanding DNA and RNA. Early and personal life Pirie was born in Easebourne, near Midhurst in West Sussex, the youngest of three children of Sir George Pirie, a Scottish painter, and his wife while they were on a visit to England. He was raised near Torrance, East Dunbartonshire. He developed a stammer, and was educated by private tutors and then spent periods at Kelvinside Academy in Glasgow, Harriston School near Dumfries, and Hastings Grammar School, and then from 1921 to 1925 at Rydal School in Colwyn Bay. He studied natural sciences (biochemistry) at Emmanuel College, Cambridge from 1925 to 1929, and became a demonstrator after graduating. He married fellow biochemist Antoinette Patey in 1931. They ...
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Easebourne
Easebourne () is a village, Anglican parish and civil parish in the Chichester District of West Sussex, England. It is half a mile (0.8 km) north of Midhurst, across the River Rother on the A272 and A286 roads. The parish includes the hamlet of Henley to the north. In the 2001 census there were 708 households with a total population of 1,717. History Easebourne (''Eseburne'') was listed in the Domesday Book of 1086 as an ancient Hundred, an extensive area reaching as far afield as Graffham and Cocking to the south, Stedham to the west and Tillington to the east, as well as two hamlets that were not parishes: Todham to the southeast and Buddington to the west; in total it included 12 settlements containing 276 households. In 1861, the population was 859, and the area of the parish . Governance An electoral ward of the same name exists. This ward includes Lodsworth and at the 2011 census had a population of 2,492. Amenities There is one public house in Easebourne, ...
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Torrance, East Dunbartonshire
Torrance is a village in East Dunbartonshire, formerly Stirlingshire, Scotland, located north of Glasgow city centre. Torrance used to mainly consist of farmland. The village was once known as a resting place for workers on their way to the Campsie Fells north. The Forth and Clyde Canal has a wharf nearby at Hungryside, and the A807 runs along its southern edge. The village has an active community charity whose aims are to improve the village facilities. History Originally located in the county of Stirlingshire the name Torrance may come from the Gaelic for the place of the "little hillocks". There are Roman sites close to Torrance with a fort at Cadder and a fortlet at Glasgow Bridge. The village of Torrance is located in "The Eleven Ploughs of Balgrochan". The "Eleven Ploughlands" are part of the estate of the Grahams of Mugdock, which had been feued in 1630 to local occupiers by the Marquess of Montrose. The feuars, originally holding their land unenclosed, each rec ...
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Tobacco Mosaic Virus
Tobacco mosaic virus (TMV) is a positive-sense single-stranded RNA virus species in the genus '' Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves (hence the name). TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by Wendell Meredith Stanley. It has a similar size to the largest synthetic molecule, known as PG5 with comparable length and diameter. History In 1886, Adolf Mayer first described the tobacco mosaic disease that could be transferred between plants, similar to bacterial infections. In 1892, Dmitri Ivanovsky gave the first concrete e ...
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Brucellosis
Brucellosis is a zoonosis spread primarily via ingestion of raw milk, unpasteurized milk from infected animals. It is also known as undulant fever, Malta fever, and Mediterranean fever. The bacteria causing this disease, ''Brucella'', are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (Coccobacillus, coccobacilli) bacteria. They function as Facultative parasite, facultative intracellular parasites, causing Chronic (medicine), chronic disease, which usually persists for life. Four species infect humans: ''B. abortus'', ''B. canis'', ''B. melitensis'', and ''B. suis''. ''B. abortus'' is less virulent than ''B. melitensis'' and is primarily a disease of cattle. ''B. canis'' affects dogs. ''B. melitensis'' is the most virulent and invasive species; it usually infects goats and occasionally sheep. ''B. suis'' is of intermediate virulence and chiefly infects pigs. Symptoms include Diaphoresis, profuse sweating and Arthralgia, joint and Myalgia, muscle pain. Brucellosis h ...
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Brucella
''Brucella'' is a genus of Gram-negative bacterium, bacteria, named after David Bruce (microbiologist), David Bruce (1855–1931). They are small (0.5 to 0.7 by 0.6 to 1.5 μm), non-Bacterial capsule, encapsulated, non-motile, facultatively intracellular coccobacillus, coccobacilli. ''Brucella'' spp. are the cause of brucellosis, which is a zoonosis transmitted by ingesting contaminated food (such as Pasteurization, unpasteurized milk products), direct contact with an infected animal, or inhalation of aerosols. Transmission from human to human, for example, through sexual intercourse, or from mother to child, is exceedingly rare, but possible. Minimum infectious exposure is between 10 and 100 organisms. The different species of ''Brucella'' are genetically very similar, although each has a slightly different host specificity. Hence, the National Center for Biotechnology Information taxonomy includes most ''Brucella'' species under ''B. melitensis''. The many names of brucel ...
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Arnold Ashley Miles
Sir Arnold Ashley Miles CBE FRS (20 March 1904 – 11 February 1988) was the Director of the Lister Institute of Preventive Medicine and Professor of Experimental Pathology in the University of London from 1952 to 1971. Early life He was born in York, Yorkshire, England. He was the second of three children and only son of Harry Miles, a draper, and his wife, Kate Elizabeth Hindley. He was educated at Bootham School, a Quaker foundation in York. However, from the age of 12, no amount of persuasion would make him conform to religious observance which he found unacceptable. From there he won an exhibition to King's College, Cambridge, to read medicine. He qualified MRCS, LRCP in 1928 at St Bartholomew's Hospital, London and, in 1929, at a relatively early age, obtained MRCP and in 1937 FRCP. Career In 1929, he became demonstrator at the London School of Hygiene and Tropical Medicine and began to develop a career in microbiology particularly immunity. In 1931 he returned to Camb ...
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Frederick Gowland Hopkins
Sir Frederick Gowland Hopkins (20 June 1861 – 16 May 1947) was an English biochemist who was awarded the Nobel Prize in Physiology or Medicine in 1929, with Christiaan Eijkman, for the discovery of vitamins. He also discovered the amino acid tryptophan, in 1901. He was President of the Royal Society from 1930 to 1935. Education and early life Hopkins was born in Eastbourne, Sussex, and initially attended the City of London School. However, he soon transferred to Alexandra Park College in Hornsey and completed his further study with the University of London External Programme (through evening classes at Birkbeck College) and the medical school at Guy's Hospital which is now part of King's College London School of Medicine. Career and research After graduating, Hopkins then taught physiology and toxicology at Guy's Hospital from 1894 to 1898. In 1898, while attending a meeting of the Physiological Society, he was invited by Sir Michael Foster to join the Physiological ...
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Campaign For Nuclear Disarmament
The Campaign for Nuclear Disarmament (CND) is an organisation that advocates unilateral nuclear disarmament by the United Kingdom, international nuclear disarmament and tighter international arms regulation through agreements such as the Nuclear Non-Proliferation Treaty. It opposes military action that may result in the use of nuclear, chemical or biological weapons, and the building of nuclear power stations in the UK. CND began in November 1957 when a committee was formed, including Canon John Collins as chairman, Bertrand Russell as president and Peggy Duff as organising secretary. The committee organised CND's first public meeting at Methodist Central Hall, Westminster, on 17 February 1958. Since then, CND has periodically been at the forefront of the peace movement in the UK. It claims to be Europe's largest single-issue peace campaign. Between 1958 and 1965 it organised the Aldermaston March, which was held over the Easter weekend from the Atomic Weapons Establis ...
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Antoinette Pirie
Antoinette Pirie ( Patey; 4 October 1905 – 11 October 1991) was a British biochemist, ophthalmologist, and educator. Biography Antoinette Patey was born in Bond Street, London. Her father was a botanist and pharmacist. She was educated at Wycombe Abbey School, and then achieved a first-class honours in natural sciences (biochemistry) from Newnham College, Cambridge in 1932. She completed her PhD at the biochemical laboratory in Cambridge under the professorship of Sir Frederick Gowland Hopkins. She married fellow biochemist Norman Pirie in 1931. They had a son and a daughter. Career In 1939, for her postdoctoral work, Pirie joined a team at the Imperial Cancer Research Fund's Mill Hill laboratories, led by Ida Mann. The team investigated the effect of mustard gas on the cornea and tumor viruses. Pirie was dedicated to the study of the eye for the rest of her life. In 1942, she accompanied Ida Mann to Oxford as her assistant at the formation of the Nuffield Laboratory of Op ...
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Emmanuel College, Cambridge
Emmanuel College is a constituent college of the University of Cambridge. The college was founded in 1584 by Sir Walter Mildmay, Chancellor of the Exchequer to Elizabeth I. The site on which the college sits was once a priory for Dominican monks, and the College Hall is built on the foundations of the monastery's nave. Emmanuel is one of the 16 "old colleges", which were founded before the 17th century. Emmanuel today is one of the larger Cambridge colleges; it has around 500 undergraduates, reading almost every subject taught within the University, and around 200 postgraduates. Among Emmanuel's notable alumni are Thomas Young, John Harvard, Graham Chapman and Sebastian Faulks. Three members of Emmanuel College have received Nobel Prizes: Ronald Norrish, George Porter (both Chemistry, 1967) and Frederick Hopkins (Medicine, 1929). In every year from 1998 until 2016, Emmanuel was among the top five colleges in the Tompkins Table, which ranks colleges according to end-of-year ...
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Rydal Penrhos
Rydal Penrhos School is a private day school in Colwyn Bay, North Wales. It is the only Methodist school in the independent sector in Wales. It is located on multiple sites around the town with a site in the neighbouring village of Rhos-on-Sea where it keeps its watersports equipment for easy access to the beach. History The school started life as five separate institutions: *Penrhos College was a Methodist girls-only boarding school founded in 1880 as a result of the generosity of Reverend Frederick Payne (1814–1895), a wealthy benefactor and Wesleyan Methodist minister who lived in Colwyn Bay. It was prominently situated above the promenade towards Rhos-on-Sea. Its motto was ''Semper ad lucem'' ("Always towards the light"). *Rydal School was founded (as Rydal Mount School) by Thomas Osborn in 1885 as a boys’ boarding school. It was named after the house – at the junction of Lansdowne Road and Pwllycrochan Avenue in Colwyn Bay – which Osborn had acquired from Reveren ...
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Hastings Grammar School
Hastings ( ) is a seaside town and borough in East Sussex on the south coast of England, east of Lewes and south east of London. The town gives its name to the Battle of Hastings, which took place to the north-west at Senlac Hill in 1066. It later became one of the medieval Cinque Ports. In the 19th century, it was a popular seaside resort, as the railway allowed tourists and visitors to reach the town. Hastings remains a popular seaside resort and is also a fishing port, with the UK's largest beach-based fishing fleet. The town's estimated population was 91,100 in 2021. History Early history The first mention of Hastings is from the late 8th century in the form ''Hastingas''. This is derived from the Old English tribal name ''Hæstingas'', meaning 'the constituency (followers) of Hæsta'. Symeon of Durham records the victory of Offa in 771 over the ''Hestingorum gens'', that is, "the people of the Hastings tribe." Hastingleigh in Kent was named after that tribe. The pla ...
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