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Norma Andrews
Norma W. Andrews is a cell biologist and professor at the University of Maryland Department of Cell Biology and Molecular Genetics. She chaired the department from 2009 to 2014. Education and career Norma Andrews received her B.S. in 1977 and Ph.D. in 1983, both from the University of São Paulo. She then went on to a postdoctoral fellowship in the laboratory of Victor Nussenzweig at New York University, which she completed in 1990. She then began her own laboratory at Yale University, where she joined the Department of Cell Biology and the Section of Microbial Pathogenesis becoming a Full Professor in 1999. In 2009, Andrews moved her lab to the University of Maryland to chair the Department of Cell Biology and Molecular Genetics. She stepped down from that position in 2014. Research Andrews' research has focused on the cell biology of mammalian cells and their response to intracellular parasitic eukaryotes such as ''Trypanosoma cruzi'' and ''Leishmania''. Her group is known for di ...
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University Of Maryland
The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public university, public Land-grant university, land-grant research university in College Park, Maryland. Founded in 1856, UMD is the Flagship university, flagship institution of the University System of Maryland. It is also the largest university in both the state and the Washington metropolitan area, with more than 41,000 students representing all fifty states and 123 countries, and a global alumni network of over 388,000. Together, its 12 schools and colleges offer over 200 degree-granting programs, including 92 undergraduate majors, 107 Master's degree, master's programs, and 83 Doctorate, doctoral programs. UMD is a member of the Association of American Universities and competes in intercollegiate athletics as a member of the Big Ten Conference. The University of Maryland's proximity to the nation's capital has resulted in many research partnerships with the Federal government ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxfor ...
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University Of São Paulo
The University of São Paulo ( pt, Universidade de São Paulo, USP) is a public university in the Brazilian state of São Paulo. It is the largest Brazilian public university and the country's most prestigious educational institution, the best university in Ibero-America, and holds a high reputation among world universities, being ranked 100 worldwide in reputation by the Times Higher Education World University Rankings. The USP is involved in teaching, research and university extension in all areas of knowledge, offering a broad range of courses. The university was founded in 1934, regrouping already existing schools in the state of São Paulo, such as the Faculdade de Direito do Largo de São Francisco (Faculty of Law), the Escola Politécnica (Engineering School) and the Escola Superior de Agricultura Luiz de Queiroz (College of Agriculture). The university's foundation is marked by the creation in 1934 of the Faculdade de Filosofia, Ciências e Letras (Faculty of Philo ...
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Victor Nussenzweig
The name Victor or Viktor may refer to: * Victor (name), including a list of people with the given name, mononym, or surname Arts and entertainment Film * ''Victor'' (1951 film), a French drama film * ''Victor'' (1993 film), a French short film * ''Victor'' (2008 film), a 2008 TV film about Canadian swimmer Victor Davis * ''Victor'' (2009 film), a French comedy * ''Victor'', a 2017 film about Victor Torres by Brandon Dickerson * ''Viktor'' (film), a 2014 Franco/Russian film Music * ''Victor'' (album), a 1996 album by Alex Lifeson * "Victor", a song from the 1979 album ''Eat to the Beat'' by Blondie Businesses * Victor Talking Machine Company, early 20th century American recording company, forerunner of RCA Records * Victor Company of Japan, usually known as JVC, a Japanese electronics corporation originally a subsidiary of the Victor Talking Machine Company ** Victor Entertainment, or JVCKenwood Victor Entertainment, a Japanese record label ** Victor Interactive So ...
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New York University
New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then- Secretary of the Treasury Albert Gallatin. In 1832, the non-denominational all-male institution began its first classes near City Hall based on a curriculum focused on a secular education. The university moved in 1833 and has maintained its main campus in Greenwich Village surrounding Washington Square Park. Since then, the university has added an engineering school in Brooklyn's MetroTech Center and graduate schools throughout Manhattan. NYU has become the largest private university in the United States by enrollment, with a total of 51,848 enrolled students, including 26,733 undergraduate students and 25,115 graduate students, in 2019. NYU also receives the most applications of any private institution in the United States and admission is considered highly selective. NYU is organiz ...
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Yale University
Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregationalism in the United States, Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and sc ...
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Trypanosoma Cruzi
''Trypanosoma cruzi'' is a species of parasitic euglenoids. Among the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: Chagas disease in humans, dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in accord with a mechanism of infection. The triatomine likes the nests of vertebrate animals for shelter, where it bites and sucks blood for food. Individual triatomines infected with protozoa from other contact with animals transmit trypanosomes when the triatomine deposits its faeces on the host's skin surface and then bites. Penetration of the infected faeces is further facilitated by the scratching of the bite area by the human or animal host. Lif ...
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Leishmania
''Leishmania'' is a parasitic protozoan, a single-celled organism of the genus '' Leishmania'' that are responsible for the disease leishmaniasis. They are spread by sandflies of the genus ''Phlebotomus'' in the Old World, and of the genus ''Lutzomyia'' in the New World. At least 93 sandfly species are proven or probable vectors worldwide.WHO (2010) Annual report. Geneva Their primary hosts are vertebrates; ''Leishmania'' commonly infects hyraxes, canids, rodents, and humans. History Members of an ancient genus of the ''Leishmania'' parasite, ''Paleoleishmania'', have been detected in fossilized sand flies dating back to the early Cretaceous period. The first written reference to the conspicuous symptoms of cutaneous leishmaniasis surfaced in the Paleotropics within oriental texts dating back to the 7th century BC (allegedly transcribed from sources several hundred years older, between 1500 and 2000 BC). Due to its broad and persistent prevalence throughout antiquity as a mys ...
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Exocytosis
Exocytosis () is a form of active transport and bulk transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell ('' exo-'' + '' cytosis''). As an active transport mechanism, exocytosis requires the use of energy to transport material. Exocytosis and its counterpart, endocytosis, are used by all cells because most chemical substances important to them are large polar molecules that cannot pass through the hydrophobic portion of the cell membrane by passive means. Exocytosis is the process by which a large amount of molecules are released; thus it is a form of bulk transport. Exocytosis occurs via secretory portals at the cell plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structure at the cell plasma membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell. In exocytosis, membrane-bound secretory vesicles are carried to the cell membrane, where ...
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Lysosome
A lysosome () is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The lumen's pH (~4.5–5.0) is optimal for the enzymes involved in hydrolysis, analogous to the activity of the stomach. Besides degradation of polymers, the lysosome is involved in various cell processes, including secretion, plasma membrane repair, apoptosis, cell signaling, and energy metabolism. Lysosomes act as the waste disposal system of the cell by digesting used materials in the cytoplasm, from both inside and outside the cell. Material from outside the cell is taken up through endocytosis, while material from the inside of the cell is digested through autophagy. The sizes of the organelles vary greatly—the larger ones can be more than 10 times the size of the smaller ones. They we ...
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Plasma Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to io ...
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Ana Rodriguez (scientist)
Ana Rodriguez is a parasitologist and Professor in the Department of Microbiology at New York University School of Medicine. Her research focuses on ''Plasmodium falciparum'' and ''Trypanosoma cruzi'' and she is known for her work on ''Plasmodium'' liver infection, ''Plasmodium'' immunity, and ''T. cruzi'' drug development. Education and career Ana Rodriguez received her Ph.D. in immunology from Universidad Autonoma de Madrid in 1993. She then went on to do postdoctoral fellowships with Norma Andrews at Yale University School of Medicine from 1993 to 1997, and Sebastian Amigorena at the Institut Curie from 1997 to 1999. In 1999, Rodriguez was hired as an instructor at the New York University School of Medicine. She was promoted to assistant professor in 2000 and associate professor in 2010. She is currently the director of the Parasitology Division of the Department of Microbiology, as well as the director of the University's Insectary Core Facility. Awards *2006: Pathogenesi ...
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