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Niels Jerne
Niels Kaj Jerne, FRS (23 December 1911 – 7 October 1994) was a Danish immunologist. He shared the Nobel Prize in Physiology or Medicine in 1984 with Georges J. F. Köhler and César Milstein "for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies". Jerne is known for three significant ideas. Firstly, instead of the body producing antibodies in response to an antigen, Jerne postulated that the immune system already has the specific antibodies it needs to fight antigens. Secondly, it was known that the immune system learns to be tolerant to the individual's own self. Jerne postulated that this learning takes place in the thymus. Thirdly, it was known that T cells and B cells communicate with each other. Jerne's network theory proposed that the active sites of antibodies are attracted to both specific antigens ( idiotypes) and to other antibodies that bind to the same ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Castillon-du-Gard
Castillon-du-Gard (; ) is a commune in the Gard department in southern France. Population Notable people * Niels Kaj Jerne (1911–1994), Danish immunologist and Nobel Prize winner, died in Castillon-du-Gard See also *Communes of the Gard department This is a list of the 350 communes of the Gard department of France. The communes cooperate in the following intercommunalities (as of 2025):Communes of Gard {{Gard-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rotterdam
Rotterdam ( , ; ; ) is the second-largest List of cities in the Netherlands by province, city in the Netherlands after the national capital of Amsterdam. It is in the Provinces of the Netherlands, province of South Holland, part of the North Sea mouth of the Rhine–Meuse–Scheldt delta, via the Nieuwe Maas, New Meuse inland shipping channel, dug to connect to the Meuse at first and now to the Rhine. Rotterdam's history goes back to 1270, when a dam was constructed in the Rotte (river), Rotte. In 1340, Rotterdam was granted city rights by William II, Count of Hainaut, William IV, Count of Holland. The Rotterdam–The Hague metropolitan area, with a population of approximately 2.7 million, is the List of urban areas in the European Union, 10th-largest in the European Union and the most populous in the country. A major logistic and economic centre, Rotterdam is Port of Rotterdam, Europe's largest seaport. In 2022, Rotterdam had a population of 655,468 and is home to over 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frankfurt
Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the foreland of the Taunus on its namesake Main (river), Main, it forms a continuous conurbation with Offenbach am Main; Frankfurt Rhein-Main Regional Authority, its urban area has a population of over 2.7 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.8 million and is Germany's Metropolitan regions in Germany, second-largest metropolitan region after the Rhine-Ruhr metropolitan region, Rhine-Ruhr region and the List of EU metropolitan regions by GDP#2021 ranking of top four German metropolitan regions, fourth largest metropolitan region by GDP in the European Union (EU). Frankfurt is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg Cit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul-Ehrlich-Institut (Germany)
The Paul Ehrlich Institute (German: ''Paul-Ehrlich-Institut – Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel'', PEI) is a German federal agency, medical regulatory body and research institution for vaccines and biomedicines. It was founded in 1896 and is subordinate to the Federal Ministry of Health. The institute is a WHO Collaborating Centre for quality assurance of blood products and ''in vitro'' diagnostic devices. It is located in Langen, Hesse, near Frankfurt, and was located in Frankfurt for most of the 20th century. It is named for its founding director, the immunologist and Nobel Prize laureate Paul Ehrlich. History The Paul Ehrlich Institute was founded on 1 June 1896 in Steglitz, Berlin as the Institute for Serum Research and Serum Testing (Institut für Serumforschung und Serumprüfung), with immunologist Paul Ehrlich, one of Germany's most prominent medical researchers at the time, as its first director. The institute was founded specifically to pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johann Wolfgang Goethe University
Goethe University Frankfurt () is a public research university located in Frankfurt am Main, Germany. It was founded in 1914 as a citizens' university, which means it was founded and funded by the wealthy and active liberal citizenry of Frankfurt. The original name in German was Universität Frankfurt am Main (University of Frankfurt am Main). In 1932, the university's name was extended in honour of one of the most famous native sons of Frankfurt, the poet, philosopher and writer/dramatist Johann Wolfgang von Goethe. The university currently has around 48,000 students, distributed across four major campuses within the city. The university celebrated its 100th anniversary in 2014. The first female president of the university, Birgitta Wolff, was sworn into office in 2015, and was succeeded by Enrico Schleiff in 2021. 20 Nobel Prize winners have been affiliated with the university, including Max von Laue and Max Born. The university is also affiliated with 18 winners of the Gottfr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pittsburgh School Of Medicine
The University of Pittsburgh School of Medicine is a medical school of the University of Pittsburgh, located in Pittsburgh, Pennsylvania. The School of Medicine, also known as Pitt Med, encompasses both a medical program, offering the doctor of medicine, and graduate programs, offering doctor of philosophy and master's degrees in several areas of biomedical science, clinical research, medical education, and medical informatics. In 2023, Pitt Med had an incoming class profile with a median score of 514 on the MCAT with a median GPA of 3.79; 8,782 people applied, and 1,020 were interviewed for 148 positions in the medical school's entering class. The School of Medicine is closely affiliated with the University of Pittsburgh Medical Center (UPMC). The School of Medicine is one of sixteen schools that comprise the University of Pittsburgh and is located in the Oakland neighborhood of the city of Pittsburgh. History Chartered on June 4, 1883, as the Western Pennsylvania Medical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiology
Microbiology () is the branches of science, scientific study of microorganisms, those being of unicellular organism, unicellular (single-celled), multicellular organism, multicellular (consisting of complex cells), or non-cellular life, acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, protistology, mycology, immunology, and parasitology. The organisms that constitute the microbial world are characterized as either prokaryotes or eukaryotes; eukaryote, Eukaryotic microorganisms possess membrane-bound organelles and include fungi and protists, whereas prokaryote, prokaryotic organisms are conventionally classified as lacking membrane-bound organelles and include Bacteria and Archaea. Microbiologists traditionally relied on culture, staining, and microscopy for the isolation and identification of microorganisms. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pittsburgh
The University of Pittsburgh (Pitt) is a Commonwealth System of Higher Education, state-related research university in Pittsburgh, Pennsylvania, United States. The university is composed of seventeen undergraduate and graduate schools and colleges at its Urban university, urban Pittsburgh campus, home to the university's central administration and around 28,000 undergraduate and graduate students. The 132-acre Pittsburgh campus includes various historic buildings that are part of the Schenley Farms Historic District, most notably its 42-story Gothic Revival architecture, Gothic revival centerpiece, the Cathedral of Learning. Pitt is a member of the Association of American Universities and is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Pitt traces its roots to the Pittsburgh Academy founded by Hugh Henry Brackenridge in 1787. While the city was still on the History of Pittsburgh#Gatewa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has 6 regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level. The WHO's purpose is to achieve the highest possible level of health for all the world's people, defining health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." The main functions of the World Health Organization include promoting the control of epidemic and endemic diseases; providing and improving the teaching and training in public health, the medical treatment of disease, and related matters; and promoting the establishment of international standards for biologic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Copenhagen
Copenhagen ( ) is the capital and most populous city of Denmark, with a population of 1.4 million in the Urban area of Copenhagen, urban area. The city is situated on the islands of Zealand and Amager, separated from Malmö, Sweden, by the Øresund strait. The Øresund Bridge connects the two cities by rail and road. Originally a Vikings, Viking fishing village established in the 10th century in the vicinity of what is now Gammel Strand, Copenhagen became the capital of Denmark in the early 15th century. During the 16th century, the city served as the ''de facto'' capital of the Kalmar Union and the seat of the Union's monarchy, which governed most of the modern-day Nordic countries, Nordic region as part of a Danish confederation with Sweden and Norway. The city flourished as the cultural and economic centre of Scandinavia during the Renaissance. By the 17th century, it had become a regional centre of power, serving as the heart of the Danish government and Military history ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Langebro
Langebro () is a bascule bridge across the Inner Harbour of Copenhagen, Denmark, connecting Zealandside H. C. Andersens Boulevard to Amagerside Amager Boulevard. It is one of only two bridges to carry motor vehicles across the harbour in central Copenhagen, the other being Knippelsbro. History 1690: The first Langebro Completed in 1690, the first bridge located roughly where Langebro is today was known as Kalvebodbro (Kalvebod Bridge) and connected the Western Rampart's Rysensteen Bastion on Zealand with Christianshavn Rampart's Christianshavns Vold#Kalvebod Bastion on Christianshavn. It was a wooden structure with a drawbridge in the middle that allowed ships to pass. The bridge was built for the military but was also open to civilian pedestrians. The bridge was refurbished several times. It was widened in 1875–76. 1903: The Swing Bridge Plans for a new Langebro were first presented in 1885 but not realized until 1903. The new bridge was located 400 ft to the sou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibody
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as pathogenic bacteria, bacteria and viruses, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens of virtually any size and chemical composition can be recognized. Antigen literally means "antibody generator", as it is the presence of an antigen that drives the formation of an antigen-specific antibody. Each of the branching chains comprising the "Y" of an antibody contains a paratope that specifically binds to one particular epitope on an antigen, allowing the two molecules to bind together with precision. Using this mechanism, antibodies can effectively "tag" the antigen (or a microbe or an infected cell bearing such an antigen) for attack by cells of the immune system, or can neutralize it directly (for example, by blocking a p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
