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Nicola Allen
Nicola J. Allen is a British neuroscientist. Allen studies the role of astrocytes in brain development, homeostasis, and aging. Her work uncovered the critical roles these cells play in brain plasticity and disease. Allen is currently an associate professor at the Salk Institute for Biological Studies and Hearst Foundation Development Chair. Education Allen conducted her undergraduate studies in Anatomical Sciences at the University of Manchester in England. She completed her doctoral degree in Neuroscience at University College London in the United Kingdom in the lab of David Attwell. She was a postdoctoral researcher in the lab of Ben Barres at Stanford University. Research Allen's research focuses on how astrocytes regulate synapses in the brain during disorders such as Alzheimer's disease. In 2012 while she was a postdoc in the lab of Ben Barres, she showed that astrocytes secrete glypican 4 and 6, which is needed to create glutamatergic synapses between neurons. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chan Zuckerberg Initiative
The Chan Zuckerberg Initiative (CZI) is an organization established and owned by Facebook founder Mark Zuckerberg and his wife Priscilla Chan with an investment of 99 percent of the couple's wealth from their Facebook shares over their lifetime. The CZI is legally set up as a limited liability company (LLC) that can be seen as a for-profit charity and is an example of philanthrocapitalism. CZI has been deemed likely to be "one of the most well-funded philanthropies in human history". Chan and Zuckerberg announced its creation on 1 December 2015, to coincide with the birth of their first child. Chan has said that her background as a child of immigrant refugees and experience as a teacher and pediatrician for vulnerable children influences how she approaches the philanthropy's work in science, education, immigration reform, housing, criminal justice, and other local issues. The Chan Zuckerberg Initiative's main areas of work include science, education, and justice and opportuni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroplasticity
Neuroplasticity, also known as neural plasticity or just plasticity, is the ability of neural networks in the brain to change through neurogenesis, growth and reorganization. Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from its prior state. This process can occur in response to learning new skills, experiencing environmental changes, recovering from injuries, or adapting to sensory or cognitive deficits. Such adaptability highlights the dynamic and ever-evolving nature of the brain, even into adulthood. These changes range from individual neuron pathways making new connections, to systematic adjustments like cortical remapping or neural oscillation. Other forms of neuroplasticity include homologous area adaptation, cross modal reassignment, map expansion, and compensatory masquerade. Examples of neuroplasticity include neural circuit, circuit and network changes that result fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year is a unit of time based on how long it takes the Earth to orbit the Sun. In scientific use, the tropical year (approximately 365 solar days, 5 hours, 48 minutes, 45 seconds) and the sidereal year (about 20 minutes longer) are more exact. The modern calendar year, as reckoned according to the Gregorian calendar, approximates the tropical year by using a system of leap years. The term 'year' is also used to indicate other periods of roughly similar duration, such as the lunar year (a roughly 354-day cycle of twelve of the Moon's phasessee lunar calendar), as well as periods loosely associated with the calendar or astronomical year, such as the seasonal year, the fiscal year, the academic year, etc. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by changes in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of The University Of Manchester
Alumni (: alumnus () or alumna ()) are former students or graduates of a school, college, or university. The feminine plural alumnae is sometimes used for groups of women, and alums (: alum) or alumns (: alumn) as gender-neutral alternatives. The word comes from Latin, meaning nurslings, pupils or foster children, derived from "to nourish". The term is not synonymous with "graduates": people can be alumni without graduating, e.g. Burt Reynolds was an alumnus of Florida State University but did not graduate. The term is sometimes used to refer to former employees, former members of an organization, former contributors, or former inmates. Etymology The Latin noun means "foster son" or "pupil". It is derived from the Latin verb "to nourish". Separate, but from the same root, is the adjective "nourishing", found in the phrase '' alma mater'', a title for a person's home university. Usage in Roman law In Latin, is a legal term (Roman law) to describe a child placed in foster ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Women Biologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories and Crown Dependencies. * British national identity, the characteristics of British people and culture * British English, the English language as spoken and written in United Kingdom of Great Britain and Northern Ireland and, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *People or things associated with: ** Great Britain, an island ** British Isles, an island group ** United Kingdom, a sovereign state ** British Empire, a historical global colonial empire ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) * British Raj, colonial India under the British Empire * British Hong Kong, colonial H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century British Women Scientists
File:1st century collage.png, From top left, clockwise: Jesus is crucified by Roman authorities in Judaea (17th century painting). Four different men (Galba, Otho, Vitellius, and Vespasian) claim the title of Emperor within the span of a year; The Great Fire of Rome (18th-century painting) sees the destruction of two-thirds of the city, precipitating the empire's first persecution against Christians, who are blamed for the disaster; The Roman Colosseum is built and holds its inaugural games; Roman forces besiege Jerusalem during the First Jewish–Roman War (19th-century painting); The Trưng sisters Trung sisters' rebellion, lead a rebellion against the Chinese Han dynasty (anachronistic depiction); Boudica, queen of the British Iceni leads Boudican revolt, a rebellion against Rome (19th-century statue); Ancient Chinese coinage, Knife-shaped coin of the Xin dynasty., 335px rect 30 30 737 1077 Crucifixion of Jesus rect 767 30 1815 1077 Year of the Four Emperors rect 1846 30 322 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century British Biologists
File:1st century collage.png, From top left, clockwise: Jesus is crucified by Roman authorities in Judaea (17th century painting). Four different men ( Galba, Otho, Vitellius, and Vespasian) claim the title of Emperor within the span of a year; The Great Fire of Rome (18th-century painting) sees the destruction of two-thirds of the city, precipitating the empire's first persecution against Christians, who are blamed for the disaster; The Roman Colosseum is built and holds its inaugural games; Roman forces besiege Jerusalem during the First Jewish–Roman War (19th-century painting); The Trưng sisters lead a rebellion against the Chinese Han dynasty (anachronistic depiction); Boudica, queen of the British Iceni leads a rebellion against Rome (19th-century statue); Knife-shaped coin of the Xin dynasty., 335px rect 30 30 737 1077 Crucifixion of Jesus rect 767 30 1815 1077 Year of the Four Emperors rect 1846 30 3223 1077 Great Fire of Rome rect 30 1108 1106 2155 Boudican ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribosome
Ribosomes () are molecular machine, macromolecular machines, found within all cell (biology), cells, that perform Translation (biology), biological protein synthesis (messenger RNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA molecules to form polypeptide chains. Ribosomes consist of two major components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomal RNA molecules and many ribosomal proteins (). The ribosomes and associated molecules are also known as the ''translational apparatus''. Overview The sequence of DNA that encodes the sequence of the amino acids in a protein is transcribed into a messenger RNA (mRNA) chain. Ribosomes bind to the messenger RNA molecules and use the RNA's sequence of nucleotides to determine the sequence of amino acids needed to generate a protein. Amino acids are selected and carried to the ribosome by transfer RNA (tRNA) molecules, which enter the riboso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glypican 6
Glypican-6 is a protein that in humans is encoded by the ''GPC6'' gene. The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. See also * Glypican Glypicans constitute one of the two major families of heparan sulfate proteoglycans, with the other major family being syndecans. Six glypicans have been identified in mammals, and are referred to as GPC1 through GPC6. In ''Drosophila'' two glypica ... References Further reading * * * * * * External links * * {{gene-13-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Attwell
David Attwell FRS, Fellow of the Academy of Medical Sciences, Member of Academia Europaea, Member of the Norwegian Academy of Science and Letters (born 1953ATTWELL, Prof. David Ian ''Who's Who 2015'', A & C Black, 2015; online edn, Oxford University Press, 2014) is a British , and the Jodrell Professor of Physiology at in the [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glypican 4
Glypican-4 is a protein that in humans is encoded by the ''GPC4'' gene. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. See also * Glypican Glypicans constitute one of the two major families of heparan sulfate proteoglycans, with the other major family being syndecans. Six glypicans have been identified in mammals, and are referred to as GPC1 through GPC6. In ''Drosophila'' two glypica ... References Further reading * * * * * * * External links GeneReviews/NIH/NCBI/UW entry on Sim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
