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NeuroLex
NeuroLex is a lexicon of neuroscience concepts supported by the Neuroscience Information Framework project, which is funded by the NIH Blueprint for Neuroscience Research. It is the lexical part of the NIF knowledge base, and NeuroLex is intended to make literature review easier and ensure consistent terminology and usage across researchers for the topics of experimental, clinical, and transnational neuroscience, and for genetic and genomic resources. It is structured as a semantic wiki, using Semantic MediaWiki. NIF provides access to resources that are relevant to neuroscience, search strategies tailored to the field, and access to content that is traditionally "hidden" from web search engines. The Framework is an inventory of neuroscience databases, annotated and integrated with a unified system of biomedical terminology (i.e., NeuroLex). NIF supports concept-based queries across multiple scales of biological structure and multiple levels of biological function. As part ...
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NeuroLex Screen Shot 2014-02-01
NeuroLex is a lexicon of neuroscience concepts supported by the Neuroscience Information Framework project, which is funded by the NIH Blueprint for Neuroscience Research. It is the lexical part of the NIF knowledge base, and NeuroLex is intended to make literature review easier and ensure consistent terminology and usage across researchers for the topics of experimental, clinical, and transnational neuroscience, and for genetic and genomic resources. It is structured as a semantic wiki, using Semantic MediaWiki. NIF provides access to resources that are relevant to neuroscience, search strategies tailored to the field, and access to content that is traditionally "hidden" from web search engines. The Framework is an inventory of neuroscience databases, annotated and integrated with a unified system of biomedical terminology (i.e., NeuroLex). NIF supports concept-based queries across multiple scales of biological structure and multiple levels of biological function. As part of ...
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Neuroscience Information Framework
The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/ genomic resources and provides many authoritative links throughout the neuroscience portal of Wikipedia. Description The Neuroscience Information Framework (NIF) is an initiative of the NIH Blueprint for Neuroscience Research, which was established in 2004 by the National Institutes of Health. Development of the NIF started in 2008, when the University of California, San Diego School of Medicine obtained an NIH contract to create and maintain "a dynamic inventory of web-based neurosciences data, resources, and tools that scientists and students can access via any computer connected to the Internet". The project is headed by Maryann Martone, co-director of the National Center for Microscopy and Imaging Research (NCMIR), part of the multi-disciplinary Center for Research in Bi ...
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NeuroNames
''NeuroNames'' is an integrated nomenclature for structures in the brain and spinal cord of the four species most studied by neuroscientists: human, macaque, rat and mouse. It offers a standard, controlled vocabulary of common names for structures, which is suitable for unambiguous neuroanatomical indexing of information in digital databases. Terms in the standard vocabulary have been selected for ease of pronunciation, mnemonic value, and frequency of use in recent neuroscientific publications. Structures and their relations to each other are defined in terms of the standard vocabulary. Currently NeuroNames contains standard names, synonyms and definitions of some 2,500 neuroanatomical entities. The nomenclature is maintained by the University of Washington and is the core component of a tool called "BrainInfo". BrainInfo helps one identify structures in the brain. One can either search by a structure name or locate the structure in a brain atlas and get information such as it ...
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Neuron
A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural network in the nervous system. They are located in the nervous system and help to receive and conduct impulses. Neurons communicate with other cells via synapses, which are specialized connections that commonly use minute amounts of chemical neurotransmitters to pass the electric signal from the presynaptic neuron to the target cell through the synaptic gap. Neurons are the main components of nervous tissue in all Animalia, animals except sponges and placozoans. Plants and fungi do not have nerve cells. Molecular evidence suggests that the ability to generate electric signals first appeared in evolution some 700 to 800 million years ago, during the Tonian period. Predecessors of neurons were the peptidergic secretory cells. They eventually ga ...
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Semantic Wiki
A semantic wiki is a wiki that has an underlying model of the knowledge described in its pages. Regular, or syntactic, wikis have structured text and untyped hyperlinks. Semantic wikis, on the other hand, provide the ability to capture or identify information about the data within pages, and the relationships between pages, in ways that can be queried or exported like a database through semantic queries. Semantic wikis were first proposed in the early 2000s, and began to be implemented seriously around 2005. As of 2021, well-known semantic wiki engines are Semantic MediaWiki and Wikibase. Key characteristics Formal notation The knowledge model found in a semantic wiki is typically available in a formal language, so that machines can process it into an entity-relationship model or relational database. The formal notation may be included in the pages themselves by users, as in Semantic MediaWiki, or it may be derived from the pages or the page names or the means of linki ...
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Semantic MediaWiki
Semantic MediaWiki (SMW) is an extension to MediaWiki that allows for annotating semantic data within wiki pages, thus turning a wiki that incorporates the extension into a semantic wiki. Data that has been encoded can be used in semantic searches, used for aggregation of pages, displayed in formats like maps, calendars and graphs, and exported to the outside world via formats like RDF and CSV. Authors Semantic MediaWiki was initially created by Markus Krötzsch, Denny Vrandečić and Max Völkel, and was first released in 2005. Its development was initially funded by the EU-funded FP6 project SEKT ( CORDIS site), and was later supported in part by Institute AIFB of the University of Karlsruhe (later renamed the Karlsruhe Institute of Technology). Currently SMW is maintained by an open-source-community on GitHub with Jeroen De Dauw as one of the lead maintainers. Basic syntax Every semantic annotation within SMW is a "property" connecting the page on which it resides to so ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. Hist ...
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Nervous System
In biology, the nervous system is the complex system, highly complex part of an animal that coordinates its behavior, actions and sense, sensory information by transmitting action potential, signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in Ediacara biota, wormlike organisms about 550 to 600 million years ago. In Vertebrate, vertebrates, it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers, or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves (efferent), while those nerves that transmit information from the body to the CNS are called sensory nerves (aff ...
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Anatomical Terminology
Anatomical terminology is a specialized system of terms used by anatomists, zoologists, and health professionals, such as doctors, surgeons, and pharmacists, to describe the structures and functions of the body. This terminology incorporates a range of unique terms, prefixes, and suffixes derived primarily from Ancient Greek and Latin. While these terms can be challenging for those unfamiliar with them, they provide a level of precision that reduces ambiguity and minimizes the risk of errors. Because anatomical terminology is not commonly used in everyday language, its meanings are less likely to evolve or be misinterpreted. For example, everyday language can lead to confusion in descriptions: the phrase "a scar above the wrist" could refer to a location several inches away from the hand, possibly on the forearm, or it could be at the base of the hand, either on the palm or dorsal (back) side. By using precise anatomical terms, such as "proximal," "distal," "palmar," or " ...
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Ontology (information Science)
In information science, an ontology encompasses a representation, formal naming, and definitions of the categories, properties, and relations between the concepts, data, or entities that pertain to one, many, or all domains of discourse. More simply, an ontology is a way of showing the properties of a subject area and how they are related, by defining a set of terms and relational expressions that represent the entities in that subject area. The field which studies ontologies so conceived is sometimes referred to as ''applied ontology''. Every academic discipline or field, in creating its terminology, thereby lays the groundwork for an ontology. Each uses ontological assumptions to frame explicit theories, research and applications. Improved ontologies may improve problem solving within that domain, interoperability of data systems, and discoverability of data. Translating research papers within every field is a problem made easier when experts from different countries mainta ...
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Neuroscience Software
Neuroscience is the science, scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a Multidisciplinary approach, multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cell biology, cellular studies of individual neur ...
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