|
Nematospiroides Dubius
''Heligmosomoides polygyrus'' is a naturally occurring intestinal roundworm of rodents. It belongs to the family Trychostrongylidae, and male and female worms are morphologically distinguishable. The parasite has a direct Biological life cycle, lifecycle, with its larval form being the infective stage. ''H. polygyrus'' has the ability to establish chronic infections in rodents and alter host immune responses. This nematode is widely used as a gastrointestinal parasitic model in immunological, pharmacological, and toxicological studies. Taxonomy The taxon consisted of the following subspecies: * ''H. polygyrus polygyrus'', found in the Western Palearctic, infects ''Apodemus'' wood mice; cannot infect ''Mus (genus), Mus'' without the help of powerful Immunosuppressive drug, immunosuppressants. The synonyms ''N. dubius'' and ''H. linstowi'' both refer to this group. * ''H. polygyrus corsicus'', found in Turkey and Corsica, infects ''Mus.'' * ''H. polygyrus bakeri'', found in house ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apodemus Sylvaticus
The wood mouse (''Apodemus sylvaticus'') is a murid rodent native to Europe and northwestern Africa. It is closely related to the yellow-necked mouse (''Apodemus flavicollis'') but differs in that it has no band of yellow fur around the neck, has slightly smaller ears, and is usually slightly smaller overall: around 90 mm (3.54 in) in length and 23 g in weight. It is found across most of Europe and is a very common and widespread species, is commensal with people and is sometimes considered a pest. Other common names are long-tailed field mouse, field mouse, common field mouse, and European wood mouse. This species is a known potential carrier of the Dobrava sequence of hantavirus which affects humans and may pose serious risks to human health. Habitat and distribution Wood mice inhabit forests, grasslands, and cultivated fields, tending to seek out more wooded areas in winter. Almost entirely nocturnal and terrestrial, wood mice burrow extensively, build nests of pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heligmosomoides Polygyrus 2
''Heligmosomoides'' is a genus of nematodes The nematodes ( or ; ; ), roundworms or eelworms constitute the phylum Nematoda. Species in the phylum inhabit a broad range of environments. Most species are free-living, feeding on microorganisms, but many are parasitic. Parasitic worms (he ... belonging to the family Heligmosomidae. The species of this genus are found in Europe and Northern America. Species: *'' Heligmosomoides aberrans'' *'' Heligmosomoides americanus'' *'' Heligmosomoides asakawae'' *'' Heligmosomoides azerbaidjani'' *'' Heligmosomoides bakeri'' *'' Heligmosomoides borealis'' *'' Heligmosomoides corsicus'' *'' Heligmosomoides desportesi'' *'' Heligmosomoides dubius'' *'' Heligmosomoides glareoli'' *'' Heligmosomoides glomerophilus'' *'' Heligmosomoides hudsoni'' *'' Heligmosomoides juvenus'' *'' Heligmosomoides kratochvili'' *'' Heligmosomoides kurilensis'' *'' Heligmosomoides laevis'' *'' Heligmosomoides longicirratum'' *'' Heligmosomoide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Helper Cell
The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system. They aid the activity of other immune cells by releasing cytokines. They are considered essential in B cell Immunoglobulin class switching, antibody class switching, breaking Cross-presentation, cross-tolerance in dendritic cells, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells are mature Th cells that express the surface protein CD4. Genetic variation in regulatory elements expressed by CD4+ cells determines susceptibility to a broad class of autoimmune diseases. Structure and function Th cells contain and release cytokines to aid other immune cells. Cytokines are small protein mediators that alter the behavior of target cells that express Receptor (biochemistry), receptors for those cytokines. These cells help polar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adaptive Immune System
The adaptive immune system (AIS), also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of specialized cells, organs, and processes that eliminate pathogens specifically. The acquired immune system is one of the two main immunity strategies found in vertebrates (the other being the innate immune system). Like the innate system, the adaptive immune system includes both humoral immunity components and cell-mediated immunity components and destroys invading pathogens. Unlike the innate immune system, which is pre-programmed to react to common broad categories of pathogen, the adaptive immune system is highly specific to each particular pathogen the body has encountered. Adaptive immunity creates immunological memory after an initial response to a specific pathogen, and leads to an enhanced response to future encounters with that pathogen. Antibodies are a critical part of the adaptive immune system. Adaptive im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Innate Immune System
The innate immune system or nonspecific immune system is one of the two main immunity strategies in vertebrates (the other being the adaptive immune system). The innate immune system is an alternate defense strategy and is the dominant immune system response found in plants, fungi, prokaryotes, and invertebrates (see #Beyond vertebrates, Beyond vertebrates).. The major functions of the innate immune system are to: * recruit immune cells to infection sites by producing chemical factors, including chemical mediators called cytokines * activate the complement cascade to identify bacteria, activate cells, and promote clearance of immune complex, antibody complexes or dead cells * identify and remove foreign substances present in organs, tissues, blood and lymph, by specialized white blood cells * activate the adaptive immune system through antigen presentation * act as a physical and chemical barrier to infectious agents; via physical measures such as skin and mucus, and chemical me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helminths
Parasitic worms, also known as helminths, are a polyphyletic group of large macroparasites; adults can generally be seen with the naked eye. Many are intestinal worms that are soil-transmitted and infect the gastrointestinal tract. Other parasitic worms such as schistosomes reside in blood vessels. Some parasitic worms, including leeches and monogeneans, are ectoparasites thus, they are not classified as helminths, which are endoparasites. Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts' ability to absorb nutrients. This can cause weakness and disease in the host, and poses a global health and economic problem. Parasitic worms cannot reproduce entirely within their host's body; they have a life cycle that includes some stages that need to take place outside of the host. Helminths are able to survive in their mammalian hosts for many years due to their ability to manipulate the host's immune respons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
House Mouse
The house mouse (''Mus musculus'') is a small mammal of the rodent family Muridae, characteristically having a pointed snout, large rounded ears, and a long and almost hairless tail. It is one of the most abundant species of the genus '' Mus''. Although a wild animal, the house mouse has benefited significantly from associating with human habitation to the point that truly wild populations are significantly less common than the synanthropic populations near human activity. The house mouse has been domesticated as the pet or fancy mouse, and as the laboratory mouse, which is one of the most important model organisms in biology and medicine. The complete mouse reference genome was sequenced in 2002. Characteristics House mice have an adult body length (nose to base of tail) of and a tail length of . The weight is typically . In the wild they vary in color from grey and light brown to black (individual hairs are actually agouti coloured), but domesticated fancy mice and l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Correlation
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. Although in the broadest sense, "correlation" may indicate any type of association, in statistics it usually refers to the degree to which a pair of variables are '' linearly'' related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. However, in g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxfordshire
Oxfordshire ( ; abbreviated ''Oxon'') is a ceremonial county in South East England. The county is bordered by Northamptonshire and Warwickshire to the north, Buckinghamshire to the east, Berkshire to the south, and Wiltshire and Gloucestershire to the west. The city of Oxford is the largest settlement and county town. The county is largely rural, with an area of and a population of 691,667. After Oxford (162,100), the largest settlements are Banbury (54,355) and Abingdon-on-Thames (37,931). For local government purposes Oxfordshire is a non-metropolitan county with five districts. The part of the county south of the River Thames, largely corresponding to the Vale of White Horse district, was historically part of Berkshire. The lowlands in the centre of the county are crossed by the River Thames and its tributaries, the valleys of which are separated by low hills. The south contains parts of the Berkshire Downs and Chiltern Hills, and the north-west includes part o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wood Mouse
The wood mouse (''Apodemus sylvaticus'') is a Muridae, murid rodent native to Europe and northwestern Africa. It is closely related to the yellow-necked mouse (''Apodemus flavicollis'') but differs in that it has no band of yellow fur around the neck, has slightly smaller ears, and is usually slightly smaller overall: around 90 mm (3.54 in) in length and 23 g in weight. It is found across most of Europe and is a very common and widespread species, is commensal with people and is sometimes considered a pest. Other common names are long-tailed field mouse, field mouse, common field mouse, and European wood mouse. This species is a known potential carrier of the Dobrava sequence of hantavirus which affects humans and may pose serious risks to human health. Habitat and distribution Wood mice inhabit forests, grasslands, and cultivated fields, tending to seek out more wooded areas in winter. Almost entirely nocturnal and terrestrial, wood mice burrow extensively, build ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbial Cyst
A microbial cyst is a resting or dormant stage of a microorganism, that can be thought of as a state of suspended animation in which the metabolic processes of the cell are slowed and the cell ceases all activities like feeding and locomotion. Many groups of single-celled, microscopic organisms, or microbes, possess the ability to enter this dormant state. Encystment, the process of cyst formation, can function as a method for dispersal and as a way for an organism to survive in unfavorable environmental conditions. These two functions can be combined when a microbe needs to be able to survive harsh conditions between habitable environments (such as between hosts) in order to disperse. Cysts can also be sites for nuclear reorganization and cell division, and in parasitic species they are often the infectious stage between hosts. When the encysted microbe reaches an environment favorable to its growth and survival, the cyst wall breaks down by a process known as excystation. E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Submucosa
The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle). The submucosa ('' sub-'' + ''mucosa'') is to a mucous membrane what the subserosa ('' sub-'' + ''serosa'') is to a serous membrane. Structure Blood vessels, lymphatic vessels, and nerves (all supplying the mucosa) will run through here. In the intestinal wall, tiny parasympathetic ganglia are scattered around forming the submucous plexus (or "Meissner's plexus") where preganglionic parasympathetic neurons synapse with postganglionic nerve fibers that supply the muscularis mucosae. Histologically, the wall of the alimentary canal shows four distinct layers (from the lumen moving out): mucosa, submuc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
