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Negombata Magnifica
''Negombata magnifica'', commonly known as toxic finger-sponge, is a species of sponge found from the Red Sea and the Indian Ocean. Its reddish-brown narrow crooked branches can grow up to . ''Negombata magnifica'' is extremely toxic because of the toxin latrunculin The latrunculins are a family of natural products and toxins produced by certain sponges, including genus ''Latrunculia'' and '' Negombata'', whence the name is derived. It binds actin monomers near the nucleotide binding cleft with 1:1 stoichiome .... ''Negombata magnifica'' lives on shallow coral reefs in the northern waters of the Red Sea . Unlike many other species of sponges that live in abundance in these waters, preferring to grow between corals and rocks, or under them, ''Negombata magnifica'' grows in sight. The local fish won't touch it so it doesn't get damaged. When touched it releases a strongly smelling, reddish juice, which instantaneously makes all the fish flee away. ''Negombata magnifica'' is gr ...
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Species
In biology, a species is the basic unit of Taxonomy (biology), classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can reproduction, produce Fertility, fertile offspring, typically by sexual reproduction. Other ways of defining species include their karyotype, DNA sequence, morphology (biology), morphology, behaviour or ecological niche. In addition, paleontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. However, only about 14% of these had been described by 2011. All species (except viruses) are given a binomial nomenclature, two-part name, a "binomial". The first part of a binomial is the genus to which the species belongs. The second part is called the specifi ...
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Sponge
Sponges, the members of the phylum Porifera (; meaning 'pore bearer'), are a basal animal clade as a sister of the diploblasts. They are multicellular organisms that have bodies full of pores and channels allowing water to circulate through them, consisting of jelly-like mesohyl sandwiched between two thin layers of cells. Sponges have unspecialized cells that can transform into other types and that often migrate between the main cell layers and the mesohyl in the process. Sponges do not have nervous, digestive or circulatory systems. Instead, most rely on maintaining a constant water flow through their bodies to obtain food and oxygen and to remove wastes. Sponges were first to branch off the evolutionary tree from the last common ancestor of all animals, making them the sister group of all other animals. Etymology The term ''sponge'' derives from the Ancient Greek word ( 'sponge'). Overview Sponges are similar to other animals in that they are multicell ...
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Red Sea
The Red Sea ( ar, البحر الأحمر - بحر القلزم, translit=Modern: al-Baḥr al-ʾAḥmar, Medieval: Baḥr al-Qulzum; or ; Coptic: ⲫⲓⲟⲙ ⲛ̀ϩⲁϩ ''Phiom Enhah'' or ⲫⲓⲟⲙ ⲛ̀ϣⲁⲣⲓ ''Phiom ǹšari''; Tigrinya: ቀይሕ ባሕሪ ''Qeyih Bahri''; ) is a seawater inlet of the Indian Ocean, lying between Africa and Asia. Its connection to the ocean is in the south, through the Bab el Mandeb strait and the Gulf of Aden. To its north lie the Sinai Peninsula, the Gulf of Aqaba, and the Gulf of Suez (leading to the Suez Canal). It is underlain by the Red Sea Rift, which is part of the Great Rift Valley. The Red Sea has a surface area of roughly 438,000 km2 (169,100 mi2), is about 2250 km (1398 mi) long, and — at its widest point — 355 km (220.6 mi) wide. It has an average depth of 490 m (1,608 ft), and in the central ''Suakin Trough'' it reaches its maximum depth of . The Red Sea also ha ...
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Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Les ...
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Latrunculin
The latrunculins are a family of natural products and toxins produced by certain sponges, including genus ''Latrunculia'' and '' Negombata'', whence the name is derived. It binds actin monomers near the nucleotide binding cleft with 1:1 stoichiometry and prevents them from polymerizing. Administered ''in vivo'', this effect results in disruption of the actin filaments of the cytoskeleton, and allows visualization of the corresponding changes made to the cellular processes. This property is similar to that of cytochalasin, but has a narrow effective concentration range. Latrunculin has been used to great effect in the discovery of cadherin distribution regulation and has potential medical applications. Latrunculin A, a type of the toxin, was found to be able to make reversible morphological changes to mammalian cells by disrupting the actin network. Latrunculin A: Target and functions Gelsolin - Latrunculin A causes end- blocking; this protein binds to the barbed sides of the a ...
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Poecilosclerida
Poecilosclerida is an order of the demosponge class. It is the most speciose demosponge order with over 2200 species (World Porifera Database). It contains about 25 recognised families. They are characterised by having chelae microscleres, that is, the minute spicules scattered through the tissues, usually in the 10-60  μm range, have a shovel-like structure on the end. Most of the families are viviparous with parenchymella larvae that are uniformly ciliated The cilium, plural cilia (), is a membrane-bound organelle found on most types of eukaryotic cell, and certain microorganisms known as ciliates. Cilia are absent in bacteria and archaea. The cilium has the shape of a slender threadlike projec .... Families As of 2018, the following families are recognized: References {{demosponge-stub ...
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