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Natural Anthraquinone
''For the parent molecule 9,10-anthraquinone, see anthraquinone'' Anthraquinones (also known as anthraquinonoids) are a class of naturally occurring phenolic compounds based on the 9,10-anthraquinone skeleton. They are widely used industrially and occur naturally. The name "anthraquinone" was first used by German chemists Carl Graebe and Carl Theodore Liebermann in a 1868 publication describing the chemical synthesis of the red dye alizarin from anthracene, a component of coal tar. This discovery led to the industrial production of alizarin and the impetus for further research on anthraquinone chemistry. Occurrence in plants : Natural pigments that are derivatives of anthraquinone are found, inter alia, in aloe latex, senna, rhubarb, and cascara buckthorn, fungi, lichens, and some insects. A type II polyketide synthase is responsible for anthraquinone biosynthesis in the bacterium ''Photorhabdus luminescens''. Chorismate, formed by isochorismate synthase in the shikima ...
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Anthraquinone
Anthraquinone, also called anthracenedione or dioxoanthracene, is an aromatic hydrocarbon, aromatic organic compound with formula . Several isomers exist but these terms usually refer to 9,10-anthraquinone (IUPAC: 9,10-dioxoanthracene) wherein the ketone, keto groups are located on the central ring. It is used as a digester additive to Pulp (paper), wood pulp for papermaking. Many Anthraquinones, anthraquinone derivatives are generated by organisms or synthesised industrially for use as Anthraquinone dyes, dyes, pharmaceuticals, and Catalysis, catalysts. Anthraquinone is a yellow, highly crystalline solid, poorly solubility, soluble in water but soluble in hot organic solvents. It is almost completely insoluble in ethanol near room temperature but 2.25 g will dissolve in 100 g of boiling ethanol. It is found in nature as the rare mineral hoelite. Synthesis There are several current industrial methods to produce 9,10-anthraquinone: # The oxidation of anthracene. Chromium(VI) is the ...
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Insect
Insects (from Latin ') are Hexapoda, hexapod invertebrates of the class (biology), class Insecta. They are the largest group within the arthropod phylum. Insects have a chitinous exoskeleton, a three-part body (Insect morphology#Head, head, Thorax (insect anatomy), thorax and abdomen (insect anatomy), abdomen), three pairs of jointed Arthropod leg, legs, compound eyes, and a pair of antenna (biology), antennae. Insects are the most diverse group of animals, with more than a million described species; they represent more than half of all animal species. The insect nervous system consists of a insect brain, brain and a ventral nerve cord. Most insects reproduce Oviparous, by laying eggs. Insects Respiratory system of insects, breathe air through a system of Spiracle (arthropods), paired openings along their sides, connected to Trachea#Invertebrates, small tubes that take air directly to the tissues. The blood therefore does not carry oxygen; it is only partly contained in ves ...
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Hydrogen Peroxide
Hydrogen peroxide is a chemical compound with the formula . In its pure form, it is a very pale blue liquid that is slightly more viscosity, viscous than Properties of water, water. It is used as an oxidizer, bleaching agent, and antiseptic, usually as a dilute solution (3%–6% by weight) in water for consumer use and in higher concentrations for industrial use. Concentrated hydrogen peroxide, or "high-test peroxide", decomposes explosively when heated and has been used as both a monopropellant and an oxidizer in rocketry. Hydrogen peroxide is a reactive oxygen species and the simplest peroxide, a compound having an oxygen–oxygen single bond. It decomposes slowly into water and elemental oxygen when exposed to light, and rapidly in the presence of organic or reactive compounds. It is typically stored with a Stabilizer (chemistry), stabilizer in a weakly acidic solution in an opaque bottle. Hydrogen peroxide is found in biological systems including the human body. Enzymes that u ...
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Fagopyrin
Fagopyrin is a term used for several closely related naturally occurring substances in the buckwheat plant. Their chemical structure contains a naphthodianthrone skeleton similar to that of hypericin. Fagopyrin is located almost exclusively in the cotyledons of the buckwheat herb. When ingested, fagopyrins cause sensitivity to light. References External linksPhytopharmaka VII: Forschung und klinische Anwendung
Piperidines Hydroxyarenes Plant toxins Quinones {{aromatic-stub ...
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Hypericin
Hypericin is a carbopolycyclic compound derived from bisanthene with antidepressant properties, found in various ''Hypericum'' species, and is being studied for treating cutaneous T-cell lymphoma. Opinions differ on the extent to which hypericin exhibits antidepressant effects. According to some scholars, hypericin, along with other active compounds in ''Hypericum perforatum'' (St. John’s wort), contributes to the antidepressant effects of the total plant extract. According to others, hypericin does not significantly inhibit monoamine oxidase and thus is unlikely to account for the antidepressant effects of ''Hypericum'' extract. While another hypericin shows affinity mainly for NMDA receptors, suggesting that other plant constituents likely play a more significant role in its antidepressant effects. Hypericin is a structurally complex phenanthroperylene quinone with potential Evidence-based medicine, medical and photoreceptive applications. It is red-colored, photosensiti ...
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Aloe
''Aloe'' (; also written ''Aloë'') is a genus containing over 650 species of flowering plant, flowering succulent plant, succulent plants.WFO (2022): Aloe L. Published on the Internet;http://www.worldfloraonline.org/taxon/wfo-4000001341. Accessed on: 06 Nov 2022 The most widely known species is ''Aloe vera'', or "true aloe". It is called this because it is cultivated as the standard source for assorted pharmaceutical purposes. Other species, such as ''Aloe ferox'', are also cultivated or harvested from the wild for similar applications. The APG IV system (2016) places the genus in the family Asphodelaceae, subfamily Asphodeloideae. Within the subfamily it may be placed in the tribe Aloeae.Stevens, P.F. (2001 onwards).Asphodelaceae. ''Angiosperm Phylogeny Website''. Retrieved 2016-06-09. In the past, it has been assigned to the family Aloaceae (now included in the Asphodeloidae) or to a broadly Circumscription (taxonomy), circumscribed family Liliaceae (the lily family). The ...
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Aloe-emodin
Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kinds of radiation. Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of ''Frangula'' (''Rhamnus frangula'') and cascara sagrada (''Rhamnus purshiana''), the leaves of Senna ('' Cassia angustifolia''), and the rhizome of rhubarb (''Rheum rhaponticum''). Aloe-emodin has not been found in Natal aloes. References See also * Emodin Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is an organic compound. Classified as an anthraquinone, it can be isolated from rhubarb, buckthorn, and Japanese knotweed ('' Reynoutria japonica'' syn. ''Polygonum cuspidatum''). Emodin is part ... {{Anthraquin ...
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Frangula Alnus
''Frangula alnus'', commonly known as alder buckthorn, glossy buckthorn, or breaking buckthorn, is a tall deciduous shrub in the family Rhamnaceae. Unlike other "buckthorns", alder buckthorn does not have thorns. It is native to Europe, northernmost Africa, and western Asia, from Ireland and Great Britain north to the 68th parallel north, 68th parallel in Scandinavia, east to central Siberia and Xinjiang in western China, and south to northern Morocco, Turkey, and the Alborz in Iran and Caucasus Mountains, the Caucasus Mountains; in the northwest of its range (Ireland, Scotland), it is rare and scattered. It is also introduced and naturalisation (biology), naturalised in eastern North America.Rushforth, K. (1999). ''Trees of Britain and Europe''. Collins .Flora Europaea''Frangula alnus''/ref>Stace, Clive, et al. ''Interactive Flora of NW Europe''''Frangula alnus''/ref> Description Alder buckthorn is a non-spiny deciduous shrub, growing to , occasionally to tall. It is usually ...
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Senna (plant)
''Senna'', the sennas, is a large genus of flowering plants in the legume family (Fabaceae, subfamily Caesalpinioideae, tribe ''Cassieae'' ser. ''Aphyllae'' ). This diverse genus is native throughout the tropics, with a small number of species in temperate regions. The number of species is estimated to be from about 260 to 350. Randell, B. R. and B. A. Barlow. 1998. ''Senna''. pp 89-138. In: A. S. George (executive editor). ''Flora of Australia'' volume 12. Australian Government Publishing Service: Canberra, Australia. The type species for the genus is '' Senna alexandrina''. About 50 species of ''Senna'' are known in cultivation.Huxley, A., et al. (1992). ''The New Royal Horticultural Society Dictionary of Gardening''. The Macmillan Press, Limited: London. The Stockton Press: New York. (set). Description Plants in the genus ''Senna'' are shrubs, sometimes small trees or perennial herbs. The leaves are arranged alternately, paripinnate with up to 25 pairs of leaflets, each leaf ...
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Senna Glycoside
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken orally (swallowed by mouth) or via the rectum. It typically begins working in around 30 minutes when given by rectum and within twelve hours when given orally. It is a weaker laxative than bisacodyl and castor oil. Common side effects of senna glycoside include abdominal cramps. It is not recommended for long-term use, as it may result in poor bowel function or electrolyte problems. While no harm has been found to result from use while breastfeeding, such use is not typically recommended. It is not typically recommended in children. Senna may change urine to a somewhat reddish color. Senna derivatives are a type of stimulant laxative and are of the anthraquinone type. While its mechanism of action is not entirely clear, senna is thought to act by increasing fluid secretion within and contraction of the large intest ...
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Morinda Citrifolia
''Morinda citrifolia'' is a fruit-bearing tree in the coffee family, Rubiaceae, native to Southeast Asia and Australasia, which was spread across the Pacific by Polynesian sailors. The species is now cultivated throughout the tropics and widely naturalised. There are over 100 names for this fruit across different regions, including great morinda, Indian mulberry, noni, beach mulberry, vomit fruit, awl tree, and rotten cheese fruit. The pungent odour of the fresh fruit has made it a famine food in most regions, but it remains a staple food among some cultures and is used in traditional medicine. In the consumer market, dietary supplements are sold in various formats, such as capsules and juices. Common names * Chinese: Hai ba ji, Wu ning (Singapore), Luo ling (Singapore, Taiwan) * Cook Islands, Niue, Samoa, Tonga: Nonu, noni, nenu, nano, nonu atoni, gogu atoni * English, Tahiti: Canary wood (Australia), Indian mulberry, Large-leaved Morinda, Noni (Hawaii), Noni fruit, No ...
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Isochorismate Synthase
Isochorismate synthase) is an isomerase enzyme that catalyzes the first step in the biosynthesis of vitamin K2 (menaquinone) in ''Escherichia coli''. Reaction Isochorismate synthase, belongs to the isomerase enzyme family. More specifically it is classified as an intramolecular transferase because it transfers the hydroxy group of chorismate between carbons. Isochorismate synthase catalyzes the irreversible conversion of chorismate to isochorismate: Isochorismate synthase is most active at 37 °C and at a pH between 7.5 and 8. It requires Mg2+ as a cofactor, in a concentration between 100 μM and 1 mM. Inhibitors of isochorismate synthase include: * (4''R'',5''R'')-4-hydroxy-5-(1-carboxyvinyloxy)-cyclohex-1-ene carboxylate * (4''R'',5''R'')-4-hydroxy-5-carboxymethoxy-cyclohex-1-enecarboxylate * (4''R'',5''R'')-5-(2-carboxy-allyloxy)-4-hydroxy-cyclohex-1-enecarboxylate * (4''R'',5''R'',6''S'')-6-ammonio-5- 1-carboxylatoethenyl)oxy4-hydroxycyclohex-1-ene-1-ca ...
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