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Nagai Nagayoshi
was a Japanese doctor of pharmacy and chemist. He is best known for the discovery of ephedrine and methamphetamine. Early life Nagai was born in Myōdō District, Awa Province in what is now Tokushima Prefecture, as the son of a doctor and started studying ''rangaku'' medicine at the Dutch Medical School of Nagasaki ''( Igaku-Denshujo)'' in 1864. While in Nagasaki, he made the acquaintance of Ōkubo Toshimichi, Itō Hirobumi, and other future leaders of the Meiji government. Career Nagai continued his studies at Tokyo Imperial University and became the first doctor of pharmacy in Japan. He was sent under government sponsorship to Prussia in 1871 to study at the University of Berlin. He was the only civilian in a group of military students sent to study in Great Britain and France, and he traveled by way of the United States and Great Britain. While in Berlin, he resided at the home of Japanese diplomat Aoki Shūzō. He was influenced by the lectures of von Hofmann, and rece ...
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Myōdō District, Tokushima
is a district located in Tokushima Prefecture, Japan. As of June 1, 2019, the district has an estimated population of 2,144 and a density Density (volumetric mass density or specific mass) is the ratio of a substance's mass to its volume. The symbol most often used for density is ''ρ'' (the lower case Greek letter rho), although the Latin letter ''D'' (or ''d'') can also be u ... of . The total area is . Towns and villages * Sanagōchi References Districts in Tokushima Prefecture {{Tokushima-geo-stub ...
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Tokyo Imperial University
The University of Tokyo (, abbreviated as in Japanese and UTokyo in English) is a public university, public research university in Bunkyō, Tokyo, Japan. Founded in 1877 as the nation's first modern university by the merger of several Edo period, pre-westernisation era institutions, its direct precursors include the ''Tenmongata'', founded in 1684, and the Yushima Seidō, Shōheizaka Institute. Although established under its current name, the university was renamed in 1886 and was further retitled to distinguish it from other Imperial Universities established later. It served under this name until the official dissolution of the Empire of Japan in 1947, when it reverted to its original name. Today, the university consists of 10 Faculty (division), faculties, 15 graduate schools, and 11 affiliated research institutes. As of 2023, it has a total of 13,974 undergraduate students and 14,258 graduate students. The majority of the university's educational and research facilities ...
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Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during chemical reaction, reactions with other chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the prop ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word ''professor'' is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well, and often to instructors or lecturers. Professors often conduct original research and commonly teach undergraduate, Postgraduate educa ...
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Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes Physical property, physical and Chemical property, chemical properties, and evaluation of Reactivity (chemistry), chemical reactivity to understand their behavior. The study of organic reactions includes the organic synthesis, chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical (in silico) study. The range of chemicals studied chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but a ...
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Eugenol
Eugenol is an allyl chain-substituted guaiacol, a member of the allylbenzene class of chemical compounds. It is a colorless to pale yellow, aromatic oily liquid extracted from certain essential oils especially from clove, nutmeg, cinnamon, basil and bay leaf. It is present in concentrations of 80–90% in clove bud oil and at 82–88% in clove leaf oil. Eugenol has a pleasant, spicy, clove-like scent. The name is derived from ''Eugenia caryophyllata'', the former Linnean nomenclature term for cloves. The currently accepted name is ''Syzygium aromaticum''. Biosynthesis The biosynthesis of eugenol begins with the amino acid tyrosine. L-tyrosine is converted to ''p''-coumaric acid by the enzyme tyrosine ammonia lyase (TAL). From here, ''p''-coumaric acid is converted to caffeic acid by ''p''-coumarate 3-hydroxylase using oxygen and NADPH. ''S''-Adenosyl methionine (SAM) is then used to methylate caffeic acid, forming ferulic acid, which is in turn converted to feruloyl- ...
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August Wilhelm Von Hofmann
August Wilhelm von Hofmann (8 April 18185 May 1892) was a German chemist who made considerable contributions to organic chemistry. His research on aniline helped lay the basis of the aniline-dye industry, and his research on coal tar laid the groundwork for his student Charles Mansfield's practical methods for extracting benzene and toluene and converting them into nitro compounds and amines. Hofmann's discoveries include formaldehyde, hydrazobenzene, the isonitriles, and allyl alcohol. He prepared three ethylamines and tetraethylammonium compounds and established their structural relationship to ammonia. After studying under Justus von Liebig at the University of Giessen, Hofmann became the first director of the Royal College of Chemistry, now part of Imperial College London, in 1845. In 1865 he returned to Germany to accept a position at the University of Berlin as a teacher and researcher. After his return he co-founded the German Chemical Society (''Deutsche Chemis ...
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Lecture
A lecture (from ) is an oral presentation intended to present information or teach people about a particular subject, for example by a university or college teacher. Lectures are used to convey critical information, history, background, theories, and equations. A politician's speech, a minister's sermon, or even a business person's sales presentation may be similar in form to a lecture. Usually the lecturer will stand at the front of the room and recite information relevant to the lecture's content. Though lectures are much criticised as a teaching method, universities have not yet found practical alternative teaching methods for the large majority of their courses. Critics point out that lecturing is mainly a one-way method of communication that does not involve significant audience participation but relies upon passive learning. Therefore, lecturing is often contrasted to active learning. Lectures delivered by talented speakers can be highly stimulating; at the very le ...
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Aoki Shūzō
Viscount was a Japanese politician and diplomat who served as foreign minister during the Meiji era. Early life Aoki was born to a samurai family as the son of the domain physician of Chōshū, in what is now part of San'yō-Onoda in Yamaguchi Prefecture. He studied western science and medicine (''rangaku'') at the domain school Meirinkan in Hagi, and in Nagasaki. He was then sent to Germany by the Chōshū Domain to study western law in 1868. However, while in Germany, his studies ranged over a very wide area, from western medicine, to politics, military science, and economics. From his surviving notes, he studied how to make beer, paper and paper money, carpets and rugs and techniques of western forestry management. Career Aoki returned to Japan after the Meiji Restoration, and entered the Foreign Ministry of the new Meiji government in 1873, as First Secretary to the Japanese legations to Germany, Netherlands and Austria-Hungary. He then served as Vice Foreign Minist ...
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Berlin
Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population within city limits, highest population within its city limits of any city in the European Union. The city is also one of the states of Germany, being the List of German states by area, third smallest state in the country by area. Berlin is surrounded by the state of Brandenburg, and Brandenburg's capital Potsdam is nearby. The urban area of Berlin has a population of over 4.6 million and is therefore the most populous urban area in Germany. The Berlin/Brandenburg Metropolitan Region, Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's second-largest metropolitan region after the Rhine-Ruhr region, as well as the List of EU metropolitan areas by GDP, fifth-biggest metropolitan region by GDP in the European Union. ...
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United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ...
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France
France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlantic, North Atlantic, the French West Indies, and List of islands of France, many islands in Oceania and the Indian Ocean, giving it Exclusive economic zone of France, one of the largest discontiguous exclusive economic zones in the world. Metropolitan France shares borders with Belgium and Luxembourg to the north; Germany to the northeast; Switzerland to the east; Italy and Monaco to the southeast; Andorra and Spain to the south; and a maritime border with the United Kingdom to the northwest. Its metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea. Its Regions of France, eighteen integral regions—five of which are overseas—span a combined area of and hav ...
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