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Mycobacterium Canetti
''Mycobacterium canettii'', a novel pathogenic taxon of the ''Mycobacterium tuberculosis'' complex (MTBC), was first reported in 1969 by the French microbiologist , for whom the organism has been named. It formed smooth and shiny colonies, which is highly exceptional for the MTBC. It was described in detail in 1997 on the isolation of a new strain from a 2-year-old Somali patient with lymphadenitis. It did not differ from ''Mycobacterium tuberculosis'' in the biochemical tests and in its 16S rRNA sequence. It had shorter generation time than clinical isolates of ''M. tuberculosis'' and presented a unique, characteristic phenolic glycolipid and lipo-oligosaccharide. In 1998, Pfyffer described abdominal lymphatic TB in a 56-year-old Swiss man with HIV infection who lived in Kenya. Tuberculosis caused by ''M. canettii'' appears to be an emerging disease in the Horn of Africa The Horn of Africa (HoA), also known as the Somali Peninsula, is a large peninsula and geopolitical regi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Tuberculosis Complex
The ''Mycobacterium tuberculosis'' complex (MTC or MTBC) is a genetically related group of ''Mycobacterium'' species that can cause tuberculosis in humans or other animals. It includes: * ''Mycobacterium tuberculosis'' * ''Mycobacterium africanum'' * '' Mycobacterium orygis'' * '' Mycobacterium bovis'' and the Bacillus Calmette–Guérin strain * '' Mycobacterium microti'' * '' Mycobacterium canettii'' * '' Mycobacterium caprae'' * '' Mycobacterium pinnipedii'' * '' Mycobacterium suricattae'' * '' Mycobacterium mungi'' In addition, two branches exist which have phylogenetic similarities but are not completely described: the dassie and oryx bacilli. Oryx bacilli has been recently reclassified into a separate subspecies, orygis. Members of the MTC can be distinguished from all other bacteria by the presence of 63 conserved signature indels (CSIs) present in diverse proteins that are exclusively shared by these pathogens. Due to their exclusivity for the MTC complex and presence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, aci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Horn Of Africa
The Horn of Africa (HoA), also known as the Somali Peninsula, is a large peninsula and geopolitical region in East Africa.Robert Stock, ''Africa South of the Sahara, Second Edition: A Geographical Interpretation'', (The Guilford Press; 2004), p. 26 Located on the easternmost part of the African mainland, it is the fourth largest peninsula in the world. It is composed of Somaliland, Somalia, Djibouti, Ethiopia, and Eritrea. Although not common, broader definitions include parts or all of Kenya and Sudan.John I. Saeed, ''Somali'' – Volume 10 of London Oriental and African language library, (J. Benjamins: 1999), p. 250.Sandra Fullerton Joireman, ''Institutional Change in the Horn of Africa'', (Universal-Publishers: 1997), p.1: "The Horn of Africa encompasses the countries of Ethiopia, Eritrea, Djibouti, and Somalia. These countries share similar peoples, languages, and geographical endowments." It has been described as a region of geopolitical and strategic importance, since it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acid-fast Bacilli
Acid-fastness is a physical property of certain bacterial and Eukaryote, eukaryotic cell (biology), cells, as well as some Sub-cellular, sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures. Once stained as part of a sample, these organisms can resist the acid and/or ethanol-based decolorization procedures common in many staining protocols, hence the name ''acid-fast''. The mechanisms of acid-fastness vary by species although the most well-known example is in the genus ''Mycobacterium'', which includes the species responsible for tuberculosis and leprosy. The acid-fastness of ''Mycobacteria'' is due to the high mycolic acid content of their cell walls, which is responsible for the staining pattern of poor absorption followed by high retention. Some bacteria may also be partially acid-fast, such as ''Nocardia''. Acid-fast organisms are difficult to characterize using standard microbiological techniques, though they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacteria
''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and leprosy ('' M. leprae'') in humans. The Greek prefix ''myco-'' means 'fungus', alluding to this genus' mold-like colony surfaces. Since this genus has cell walls with a waxy lipid-rich outer layer containing high concentrations of mycolic acid, acid-fast staining is used to emphasize their resistance to acids, compared to other cell types. Mycobacterial species are generally aerobic, non-motile, and capable of growing with minimal nutrition. The genus is divided based on each species' pigment production and growth rate. While most ''Mycobacterium'' species are non-pathogenic, the genus' characteristic complex cell wall contributes to evasion from host defenses. Microbiology Morphology Mycobacteria are aerobic with 0.2-0.6 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
