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Myaware
Myaware, formerly the Myasthenia Gravis Association is the leading UK charity for people with myasthenia gravis, congenital myasthenia, Lambert–Eaton myasthenic syndrome (LEMS) and ocular myasthenia. About The charity was established May 1976. The charity supports people with myasthenia and their families, increase public and medical awareness of the condition and raise funds for research and support staff. The charity’s head office is based in Derby Derby ( ) is a city and unitary authority area in Derbyshire, England. It lies on the banks of the River Derwent in the south of Derbyshire, which is in the East Midlands Region. It was traditionally the county town of Derbyshire. Derby gain .... Aim The organization provides information, advice and support, particularly to people just diagnosed with the conditions. References External links Official website {{authority control Health charities in the United Kingdom Neurology organizations ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myasthenia Gravis
Myasthenia gravis (MG) is a long-term neuromuscular junction disease that leads to varying degrees of skeletal muscle weakness. The most commonly affected muscles are those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. Onset can be sudden. Those affected often have a large thymus or develop a thymoma. Myasthenia gravis is an autoimmune disease of the neuro-muscular junction which results from antibodies that block or destroy nicotinic acetylcholine receptors (AChR) at the junction between the nerve and muscle. This prevents nerve impulses from triggering muscle contractions. Most cases are due to immunoglobulin G1 (IgG1) and IgG3 antibodies that attack AChR in the postsynaptic membrane, causing complement-mediated damage and muscle weakness. Rarely, an inherited genetic defect in the neuromuscular junction results in a similar condition known as congenital myasthenia. Babies of mothers with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lambert–Eaton Myasthenic Syndrome
Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder characterized by muscle weakness of the limbs. Around 60% of those with LEMS have an underlying malignancy, most commonly small-cell lung cancer; it is therefore regarded as a paraneoplastic syndrome (a condition that arises as a result of cancer elsewhere in the body). It is the result of antibodies against presynaptic voltage-gated calcium channels, and likely other nerve terminal proteins, in the neuromuscular junction (the connection between nerves and the muscle that they supply). The diagnosis is usually confirmed with electromyography and blood tests; these also distinguish it from myasthenia gravis, a related autoimmune neuromuscular disease. If the disease is associated with cancer, direct treatment of the cancer often relieves the symptoms of LEMS. Other treatments often used are steroids, azathioprine, which suppress the immune system, intravenous immunoglobulin, which outcompetes autoreactive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ocular Myasthenia
Ocular myasthenia gravis (MG) is a disease of the neuromuscular junction resulting in hallmark variability in muscle weakness and fatigability. MG is an autoimmune disease where anomalous antibodies are produced against the naturally occurring acetylcholine receptors in voluntary muscles. MG may be limited to the muscles of the eye (ocular MG), leading to abrupt onset of weakness/fatigability of the eyelids or eye movement. MG may also involve other muscle groups ( generalized MG). Signs and symptoms Although these blocking antibodies may be confined to one of the larger muscles responsible for moving the face or appendages or for breathing, about 90% of MG patients eventually have eye involvement. The most common symptoms are double vision ( diplopia) and eyelid drooping (ptosis), whereas the pupil is always spared. Diplopia occurs when MG affects a single extraocular muscle in one eye, limiting eye movement and leading to double vision when the eye is turned toward the affected ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derby
Derby ( ) is a city and unitary authority area in Derbyshire, England. It lies on the banks of the River Derwent in the south of Derbyshire, which is in the East Midlands Region. It was traditionally the county town of Derbyshire. Derby gained city status in 1977, the population size has increased by 5.1%, from around 248,800 in 2011 to 261,400 in 2021. Derby was settled by Romans, who established the town of Derventio, later captured by the Anglo-Saxons, and later still by the Vikings, who made their town of one of the Five Boroughs of the Danelaw. Initially a market town, Derby grew rapidly in the industrial era. Home to Lombe's Mill, an early British factory, Derby has a claim to be one of the birthplaces of the Industrial Revolution. It contains the southern part of the Derwent Valley Mills World Heritage Site. With the arrival of the railways in the 19th century, Derby became a centre of the British rail industry. Derby is a centre for advanced transport manufactu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Charities In The United Kingdom
Health, according to the World Health Organization, is "a state of complete physical, Mental health, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organization''– ''Basic Documents'', Forty-fifth edition, Supplement, October 2006. A variety of definitions have been used for different purposes over time. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive Stress (biology), stress. Some factors affecting health are due to Agency (sociology), individual choices, such as whether to engage in a high-risk behavior, while others are due to Social structure, structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
