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My Sister's Keeper (film)
''My Sister's Keeper'' is a 2009 American Melodrama, melodrama film directed by Nick Cassavetes and starring Cameron Diaz, Abigail Breslin, Sofia Vassilieva and Jason Patric. Based on Jodi Picoult's My Sister's Keeper (novel), 2004 novel of the same name, which is also based on Marissa and Anissa Ayala. On June 26, 2009, the film was released to cinemas in the United States, Canada, Ireland, Mexico, and the United Kingdom. Plot Young Kate Fitzgerald is diagnosed with acute promyelocytic leukemia, devastating her parents, firefighter Brian and lawyer Sara. As neither parent nor Kate's older brother Jesse are a genetic match, Brian and Sara conceive a Savior sibling, savior sister, Anna, through in vitro fertilization. Beginning with the harvest of her umbilical cord at birth, Anna has donated compatible blood and stem cells to Kate, and her life has been full of hospitalizations, growth hormone injections, opioid painkillers, sleeping pills, bleeding, and infections. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Nick Cassavetes
Nicholas David Rowland Cassavetes (born May 21, 1959) is an American actor, director, and writer. He has directed such films as '' She's So Lovely'' (1997), '' John Q.'' (2002), '' The Notebook'' (2004), ''Alpha Dog'' (2006), and '' My Sister's Keeper'' (2009). His acting credits include an uncredited role in '' Husbands'' (1970)—which was directed by his father, John Cassavetes—as well as roles in the films '' The Wraith'' (1986), ''Face/Off'' (1997), and '' Blow'' (2001). Early life and career Cassavetes was born in New York City, the son of Greek-American actor and film director John Cassavetes and actress Gena Rowlands. As a child, he appeared in his father's film '' Husbands'' (1970). After spending so much of his youth surrounded by the film industry, Cassavetes initially decided he did not want to go into the field. He instead attended Syracuse University on a basketball scholarship, but after an injury effectively ended his athletic career, he decided to rethink his as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Warner Bros
Warner Bros. Entertainment Inc. (WBEI), commonly known as Warner Bros. (WB), is an American film studio, filmed entertainment studio headquartered at the Warner Bros. Studios Burbank, Warner Bros. Studios complex in Burbank, California and the main namesake subsidiary of Warner Bros. Discovery (WBD). Founded on April 4, 1923, by four brothers, Harry Warner, Harry, Albert Warner, Albert, Sam Warner, Sam and Jack L. Warner, Jack Warner, the company established itself as a leader in the American film industry before diversifying into animation, television, and video games. It is one of the "Major film studios, Big Five" major American film studios and a member of the Motion Picture Association (MPA). The company is known for its film studio division, the Warner Bros. Motion Picture Group, which includes Warner Bros. Pictures, New Line Cinema, Warner Bros. Pictures Animation, Castle Rock Entertainment and the Warner Bros. Television Group. Bugs Bunny, a character created for the ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Parents' Rights Movement
The parents' rights movement is a civil rights movement primarily interested in human rights affecting parents related to family law, including child custody. Parents' rights are connected to parental responsibility and right to family life. Universal Declaration of Human Rights Article 26 of Universal Declaration of Human Rights enshrines the right of parents to choose the education for their children: Parents' rights in Convention on the Rights of the Child Article 14 of Convention on the Rights of the Child enshrines both parents' rights and parental duties against the state: Child custody Some parents' rights advocates claim that many parents' parental rights are unnecessarily terminated, and that children are separated from fathers and mothers and adopted through the actions of family courts and government social service agencies seeking to meet their own targets, rather than looking at the merits of each case. United Kingdom Fostering and adoption In June 2007, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Ad Litem
''Ad litem'' (Latin: "for the suit") is a term used in law to refer to the appointment by a court of one party to act in a lawsuit on behalf of another party such as a child or an incapacitated adult, who is deemed incapable of representing him or herself. An individual who acts in this capacity is generally called a guardian ''ad litem'' in such legal proceedings; in Scotland, curator ''ad litem'' is the equivalent term. In England and Wales, since the amendment of the Children Act 1989 established the role of children's guardian, the term is now used only in the term "guardian ''ad litem'' in Private Law proceedings under rule 9.5. The United States legal system, which at its inception was based on the English legal system, continues to use the terms "guardian ''ad litem'' and "attorney ''ad litem''. The legal system in the Republic of Ireland also uses the term guardian ''ad litem''. The term is also used in property litigation, where a person may be appointed to act o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Pro Bono
( English: 'for the public good'), usually shortened to , is a Latin phrase for professional work undertaken voluntarily and without payment. The term traditionally referred to provision of legal services by legal professionals for people who are unable to afford them. More recently, the term is used to describe specialist services provided by any professional free of charge to an individual or community. Law ''Pro bono'' legal counsel may assist an individual or group on a legal case by filing government applications or petitions. A judge may occasionally determine that the loser should compensate a winning ''pro bono'' counsel. Japan In Japan, the number of registered NPO Service Grants, which coordinates team-type ''pro bono'' programs, has increased tenfold between 2010 and 2020, and has supported more than 1,000 projects. In addition, the introduction of ''pro bono'' is gaining attention as an opportunity to promote citizen participation in corporate social responsibili ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Epilepsy
Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activity in the brain that can cause a variety of symptoms, ranging from brief lapses of awareness or muscle jerks to prolonged convulsions. These episodes can result in physical injuries, either directly, such as broken bones, or through causing accidents. The diagnosis of epilepsy typically requires at least two unprovoked seizures occurring more than 24 hours apart. In some cases, however, it may be diagnosed after a single unprovoked seizure if clinical evidence suggests a high risk of recurrence. Isolated seizures that occur without recurrence risk or are provoked by identifiable causes are not considered indicative of epilepsy. The underlying cause is often unknown, but epilepsy can result from brain injury, stroke, infections, Brain tumor, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Medical Emancipation
The mature minor doctrine is a rule of law found in the United States and Canada accepting that an unemancipated minor patient may possess the maturity to choose or reject a particular health care treatment, sometimes without the knowledge or agreement of parents, and should be permitted to do so. It is now generally considered a form of patients rights; formerly, the mature minor rule was largely seen as protecting health care providers from criminal and civil claims by parents of minors at least 15 years old. Jurisdictions may codify an age of medical consent, accept the judgment of licensed providers regarding an individual minor, or accept a formal court decision following a request that a patient be designated a mature minor, or may rely on some combination. For example, patients at least 16 may be assumed to be mature minors for this purpose, patients aged 13 to 15 may be designated so by licensed providers, and pre-teen patients may be so-designated after evaluation by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Kidney Failure
Kidney failure, also known as renal failure or end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible. Symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. Complications of acute and chronic failure include uremia, hyperkalemia, and volume overload. Complications of chronic failure also include heart disease, high blood pressure, and anaemia. Causes of acute kidney failure include low blood pressure, blockage of the urinary tract, certain medications, muscle breakdown, and hemolytic uremic syndrome. Causes of chronic kidney failure include diabetes, high blood pressure, nephrotic syndrome, and polycystic kidney diseas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Dyslexia
Dyslexia (), previously known as word blindness, is a learning disability that affects either reading or writing. Different people are affected to different degrees. Problems may include difficulties in spelling words, reading quickly, writing words, "sounding out" words in the head, pronouncing words when reading aloud and understanding what one reads. Often these difficulties are first noticed at school. The difficulties are involuntary, and people with this disorder have a normal desire to learn. People with dyslexia have higher rates of attention deficit hyperactivity disorder (ADHD), developmental language disorders, and difficulties with numbers. Dyslexia is believed to be caused by the interaction of genetic and environmental factors. Some cases run in families. Dyslexia that develops due to a traumatic brain injury, stroke, or dementia is sometimes called "acquired dyslexia" or alexia. The underlying mechanisms of dyslexia result from differences within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Umbilical Cord
In Placentalia, placental mammals, the umbilical cord (also called the navel string, birth cord or ''funiculus umbilicalis'') is a conduit between the developing embryo or fetus and the placenta. During prenatal development, the umbilical cord is physiologically and genetically part of the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta. Conversely, the fetal heart pumps low-oxygen, nutrient-depleted blood through the umbilical arteries back to the placenta. Structure and development The umbilical cord develops from and contains remnants of the yolk sac and allantois. It forms by the fifth week of human embryogenesis, development, replacing the yolk sac as the source of nutrients for the embryo. The cord is not directly connected to the mother's circulatory system, but instead joins the pla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
In Vitro Fertilization
In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating the ovulatory process, then removing an ovum or ova (egg or eggs) from the ovaries and enabling sperm to fertilise them in a culture medium in a laboratory. After a fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used to treat infertility, enable gestational surrogacy, and, in combination with pre-implantation genetic testing, avoid the transmission of abnormal genetic conditions. When a fertilised egg from egg and sperm donors implants in the uterus of a genetically unrelated surrogate, the resulting child is also genetically unrelated to the surrogate. Some countries have banned or otherwise regulated the availability of IVF treatme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Savior Sibling
A savior baby, savior sibling, or donor baby is a child who is conceived in order to provide a stem cell transplant to a sibling that is affected with a fatal disease, such as cancer or Fanconi anemia, that can best be treated by hematopoietic stem cell transplantation. Introduction The savior sibling is conceived through in vitro fertilization. Fertilized zygotes are tested for genetic compatibility (human leukocyte antigen (HLA) typing), using preimplantation genetic diagnosis (PGD), and only zygotes that are compatible with the existing child are implanted. Zygotes are also tested to make sure they are free of the original genetic disease. The procedure is controversial. Indications A ''savior sibling'' may be the solution for any disease treated by hematopoietic stem cell transplantation. It is effective against genetically detectable (mostly monogenic) diseases, e.g. Fanconi anemia, Diamond–Blackfan anemia and β-thalassemia, in the ailing sibling, since the savior si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
