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Mu-ming Poo
Mu-ming Poo (; born October 31, 1948) is a Chinese neuroscientist. He is the Paul Licht Distinguished Professor Emeritus at the University of California, Berkeley and the Founding Director of the Shanghai-based Institute of Neuroscience (ION) of the Chinese Academy of Sciences, Chinese Academy of Sciences (CAS). He was awarded the 2016 Gruber Prize in Neuroscience for his pioneering work on synaptic plasticity. At ION, Poo led a team of scientists that produced the world's first truly cloned primates, a pair of crab-eating macaques called Zhongzhong and Huahua in 2017, using somatic cell nuclear transfer (SCNT). Poo is academicians of National Academy of Sciences, National Academy of Sciences (NAS), Academia Sinica, and CAS. Early life and education Poo was born in Nanjing, Jiangsu, China on October 31, 1948. When he was one, his family moved to Taiwan because of the Chinese Communist Revolution. Influenced by his father, an aeronautical engineer, he was interested in physic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zhongzhong And Huahua
Zhong Zhong (, born 27 November 2017) and Hua Hua (, born 5 December 2017) are a pair of identical crab-eating macaques (also referred to as cynomolgus monkeys) that were created through somatic cell nuclear transfer (SCNT), the same cloning technique that produced Dolly the sheep in 1996. They are the first cloned primates produced by this technique. Unlike previous attempts to clone monkeys, the donated nuclei came from fetal cells, not embryonic cells.Scholarly sources: * *Popular sources: * * The primates were born from two independent surrogate pregnancies at the Institute of Neuroscience of the Chinese Academy of Sciences in Shanghai. Background Since scientists produced the first cloned mammal Dolly the sheep in 1996 using the somatic cell nuclear transfer (SCNT) technique, 23 mammalian species have been successfully cloned, including cattle, cats, dogs, horses and rats. Using this technique for primates had never been successful and no pregnancy had lasted more th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophoresis
Electrophoresis is the motion of charged dispersed particles or dissolved charged molecules relative to a fluid under the influence of a spatially uniform electric field. As a rule, these are zwitterions with a positive or negative net charge. Electrophoresis is used in laboratories to separate macromolecules based on their charges. The technique normally applies a negative charge called cathode so anionic protein molecules move towards a positive charge called anode. Therefore, electrophoresis of positively charged particles or molecules (cations) is sometimes called cataphoresis, while electrophoresis of negatively charged particles or molecules (anions) is sometimes called anaphoresis. Electrophoresis is the basis for analytical techniques used in biochemistry and molecular biology to separate particles, molecules, or ions by size, charge, or binding affinity, either freely or through a supportive medium using a one-directional flow of electrical charge. It is use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of a cell, being selectively permeable to ions and organic mole ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Irvine
The University of California, Irvine (UCI or UC Irvine) is a Public university, public Land-grant university, land-grant research university in Irvine, California, United States. One of the ten campuses of the University of California system, UCI offers 87 undergraduate degrees and 129 graduate and professional degrees, and roughly 30,000 undergraduates and 7,000 graduate students were enrolled at UCI as of Fall 2024. The university is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity" and had $609.6 million in research and development expenditures in 2023, ranking it 56th nationally. UCI became a member of the Association of American Universities in 1996. The university administers the UC Irvine Medical Center, a large teaching hospital in Orange, California, Orange, and UC Irvine Health Sciences, its affiliated health sciences system; the University of California, Irvine, Arboretum; and a po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Purdue University
Purdue University is a Public university#United States, public Land-grant university, land-grant research university in West Lafayette, Indiana, United States, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette, Indiana, Lafayette businessman John Purdue donated land and money to establish a college of science, technology, and agriculture; the first classes were held on September 16, 1874. Purdue University is a member of the Association of American Universities and is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Purdue enrolls the largest student body of any individual university campus in Indiana, as well as the ninth-largest foreign student population of any university in the United States. The university is home to the oldest computer science Purdue University Department of Computer Science, program in the United States. Pur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Researcher
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. According to data from the US National Science Foundation, the number of holders of PhD in biological sciences who end up in tenure track has consistently dropped from over 50% in 1973 to less than 20% in 2006. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluorescence Recovery After Photobleaching
Fluorescence recovery after photobleaching (FRAP) is a method for determining the kinetics of diffusion through tissue or cells. It is capable of quantifying the two-dimensional lateral diffusion of a molecularly thin film containing fluorescently labeled probes, or to examine single cells. This technique is very useful in biological studies of cell membrane diffusion and protein binding. In addition, surface deposition of a fluorescing phospholipid bilayer (or monolayer) allows the characterization of hydrophilic (or hydrophobic) surfaces in terms of surface structure and free energy. Similar, though less well known, techniques have been developed to investigate the 3-dimensional diffusion and binding of molecules inside the cell; they are also referred to as FRAP. Experimental setup The basic apparatus comprises an optical microscope, a light source and some fluorescent probe. Fluorescent emission is contingent upon absorption of a specific optical wavelength or color which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892. Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and bioche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aeronautical Engineer
Aerospace engineering is the primary field of engineering concerned with the development of aircraft and spacecraft. It has two major and overlapping branches: aeronautical engineering and astronautical engineering. Avionics engineering is similar, but deals with the electronics side of aerospace engineering. "Aeronautical engineering" was the original term for the field. As flight technology advanced to include vehicles operating in outer space, the broader term "aerospace engineering" has come into use. Aerospace engineering, particularly the astronautics branch, is often colloquially referred to as "rocket science". Overview Flight vehicles are subjected to demanding conditions such as those caused by changes in atmospheric pressure and temperature, with structural loads applied upon vehicle components. Consequently, they are usually the products of various technological and engineering disciplines including aerodynamics, air propulsion, avionics, materials science, st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chinese Communist Revolution
The Chinese Communist Revolution was a social revolution, social and political revolution in China that began in 1927 and culminated with the proclamation of the People's Republic of China (PRC) in 1949. The revolution was led by the Chinese Communist Party (CCP), which afterwards became the ruling party of China. The political revolution resulted in major social changes within China and has been looked at as a model by revolutionary Communist movements in other countries. During the preceding century, termed the century of humiliation, the decline of the Qing dynasty and the rise of foreign imperialism caused escalating social, economic, and political problems in China. The Qing collapsed in 1912 and were replaced with the Republic of China (1912–1949), Republic of China, which had itself fallen into Warlord Era, warring factions by 1917. A small group of urban intellectuals, inspired by the October Revolution and European socialist ideas, founded the CCP in 1921. They creat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
