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Moses Chao
Moses V. Chao (born May 16, 1952) is a neuroscientist and university professor at NYU Langone Health Medical Center. He studies the mechanisms of neuronal growth factor and teaches courses in cell biology, neuroscience, and physiology. He is a Fellow of the American Association for the Advancement of Science and was President of the Society for Neuroscience in 2012. Early life and education In 1972, Chao earned a Bachelor of Arts degree in biochemistry at Pomona College in Claremont, California. In 1980, he earned a Ph.D. in biochemistry at University of California, Los Angeles. He researched chromatin structure at the Molecular Biology Institute at UCLA. After earning his doctorate, Chao worked as a research fellow at Columbia University from 1980 to 1983, where he carried out his postdoctoral research with molecular biologist Richard Axel. Research Since 2019, Chao has been a lead investigator at New York University investigating the mechanisms behind specificity of neuronal ...
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Neuroscientist
A neuroscientist (or neurobiologist) is a scientist specializing in neuroscience that deals with the anatomy and function of neurons, Biological neural network, neural circuits, and glia, and their Behavior, behavioral, biological, and psychological roles in health and disease. Neuroscientists generally work as researchers within a college, university, government agency, or private Private industry, industry setting. In research-oriented careers, neuroscientists design and conduct scientific experiments on the nervous system and its functions. They can engage in basic or applied research. Basic research seeks to expand current understanding of the nervous system, whereas applied research seeks to address a specific problem, such as developing a treatment for a neurological disorder. Neuroscientists have numerous career opportunities outside of academic research, including careers in industry, science writing, government program management, science advocacy, and education. A ...
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Synapses
In the nervous system, a synapse is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are known to produce synchronous network activity in the brain, but can also result in complicated, chaotic network level dynamics. Therefore, signal directionality cannot always be defined across electrical synapses. Chemical synapses, on the other hand, communicate through neurotransmitters released from the presynaptic neuron into the synaptic cleft. Upon release, these neurotransmitters bind to specific receptors on the postsynaptic membrane, inducing an electrical or chemical response in the target neuron. T ...
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Simons Foundation
The Simons Foundation is an American private foundation established in 1994 by Marilyn and James Harris Simons, Jim Simons with offices in New York City. As one of the largest charitable organizations in the United States with assets of over $5 billion in 2022, the foundation's mission is to advance the frontiers of research in mathematics and basic sciences. The foundation supports science by making grants to individual researchers and their projects. In 2021, Marilyn Simons stepped down as president after 26 years at the helm, and Astrophysics, astrophysicist David Spergel was appointed president. The Flatiron Institute In 2016, the foundation launched the Flatiron Institute, its in-house multidisciplinary research institute focused on computational science. The Flatiron Institute hosts centers for computational science in five areas: Funding areas The foundation makes grants in four program areas: Simons Investigators awardees Among other programs, the Simons Foundat ...
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Christopher And Dana Reeve Foundation
The Christopher & Dana Reeve Foundation is a charitable organization headquartered in Short Hills, New Jersey, dedicated to finding treatments and cures for paralysis caused by spinal cord injury and other neurological disorders. The organization's mission statement states: "We are dedicated to curing spinal cord injury by advancing innovative research and improving quality of life for individuals and families impacted by paralysis." , it has distributed over $140 million to spinal cord researchers, and $46 million to nonprofits that aim to support better quality-of-life for people with disabilities. History The foundation was started in 1982 by Hank Stifel, whose son Henry had been injured in a motor vehicle accident. Its original name was the Stifel Paralysis Research Foundation. In the mid-1980s, Stifel approached the American Paralysis Association (APA) about a merger under the APA banner. In 1995, actor Christopher Reeve became quadriplegic as a result of a horse riding a ...
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Journal Of Biological Chemistry
The ''Journal of Biological Chemistry'' (''JBC'') is a weekly peer-reviewed scientific journal that was established in 1905., jbc.org Since 1925, it is published by the American Society for Biochemistry and Molecular Biology. It covers research in areas of biochemistry and molecular biology. The editor is Alex Toker. the journal is fully open access. In press articles are available free on its website immediately after acceptance. Editors The following individuals have served as editors of the journal: * 1906–1909: John Jacob Abel and Christian Archibald Herter * 1909–1910: Christian Archibald Herter * 1910–1914: Alfred Newton Richards * 1914–1925: Donald D. Van Slyke * 1925–1936: Stanley R. Benedict. After Benedict died, John T. Edsall served as temporary editor until the next editor was appointed. * 1937–1958: Rudolph J. Anderson * 1958–1967: John T. Edsall * 1968–1971: William Howard Stein * 1971–2011: Herbert Tabor * 2011–2015: Martha Fedor * ...
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Molecular And Cellular Neuroscience
''Molecular and Cellular Neuroscience'' is a bimonthly peer-reviewed scientific journal covering all aspects of neurosciences. The editors-in-chief are Mathias Bähr (University of Göttingen), Alain Chédotal (Sorbonne University), Henrik Zetterberg (University of Gothenburg), and Noam E. Ziv ( Technion). According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 4.626. References External links * Neuroscience journals Elsevier academic journals Bimonthly journals English-language journals Academic journals established in 1990 {{neuroscience-journal-stub ...
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The Journal Of Neuroscience
''The Journal of Neuroscience'' is a weekly peer-reviewed scientific journal published by the Society for Neuroscience. It covers empirical research on all aspects of neuroscience. Its editor-in-chief is Sabine Kastner (Princeton University), who succeeded Marina Picciotto (Yale University) in 2024. According to the ''Journal Citation Reports'', the journal has a 2023 impact factor of 4.4. History The journal was established in 1981 and issues appeared monthly; as its popularity grew it switched to a biweekly schedule in 1996 and then to a weekly in July 2003. Themes Main themes Articles appear within one of the following five sections of the journal: * Cellular/Molecular * Development/Plasticity/Repair * Systems/Circuits * Behavioral/Cognitive * Neurobiology of Disease The journal has revised its sections over the years. In 2004, it added the Neurobiology of Disease section due to the growing number of papers on this subject. In January 2013, the journal split the section Behavi ...
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Weill Cornell Medicine
Weill Cornell Medicine (; officially Joan and Sanford I. Weill Medical College of Cornell University), originally Cornell University Medical College, is the medical school of Cornell University, located on the Upper East Side of Manhattan in New York City. The school and its associated research organization is affiliated with several hospitals and medical centers, including NewYork-Presbyterian Hospital, Weill Cornell Medical Center, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, and Rockefeller University, all of which are located on or near York Avenue and Sutton Place. Since 2004, Weill Cornell has also been affiliated with The Methodist Hospital, Houston Methodist Hospital. In 1991, Memorial Sloan Kettering Cancer Center and Rockefeller University joined Weill Cornell to establish the Tri-Institutional MD–PhD Program. In 2001, the school opened the Weill Cornell Medical College in Qatar, a medical school in Qatar. History 19th century The Cornell ...
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NYU Langone Medical Center
NYU Langone Health is an integrated Health system, academic health system located in New York City, New York, United States. The health system consists of the New York University Grossman School of Medicine, NYU Grossman School of Medicine and NYU Grossman Long Island School of Medicine, both part of New York University (NYU), and more than 320 locations throughout the New York City Region and Florida, including seven inpatient facilities: #Tisch Hospital, Tisch Hospital; #Kimmel Pavilion, Kimmel Pavilion; #NYU Langone Orthopedic Hospital, NYU Langone Orthopedic Hospital; Hassenfeld Children's Hospital; NYU Langone Hospital – Brooklyn, NYU Langone Hospital–Brooklyn; NYU Langone Hospital – Long Island, NYU Langone Hospital–Long Island; and NYU Langone Hospital — Suffolk. It is also home to #Rusk Rehabilitation, Rusk Rehabilitation. NYU Langone Health is one of the largest Hospital network, healthcare systems in the Northeastern United States, Northeast, with more than 53,0 ...
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Depression (mood)
Depression is a mental state of low Mood (psychology), mood and aversion to activity. It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. Depression affects a person's thoughts, behavior, feelings, and subjective well-being, sense of well-being. The pleasure or joy that a person gets from certain experiences is reduced, and the afflicted person often experiences a loss of motivation or interest in those activities. People with depression may experience sadness, feelings of dejection or hopelessness, difficulty in thinking and concentration, or a significant change in appetite or time spent sleeping; Suicidal ideation, suicidal thoughts can also be experienced. Depression can have multiple, sometimes overlapping, origins. Depression can be a symptom of some mood disorders, some of which are also commonly called ''depression'', such as major depressive disorder, bipolar disorder and dysthymia. Additionally, depression can be a norm ...
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Anxiety Disorder
Anxiety disorders are a group of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal functions are significantly impaired. Anxiety may cause physical and cognitive symptoms, such as restlessness, irritability, easy fatigue, difficulty concentrating, increased heart rate, chest pain, abdominal pain, and a variety of other symptoms that may vary based on the individual. In casual discourse, the words ''anxiety'' and ''fear'' are often used interchangeably. In clinical usage, they have distinct meanings; anxiety is clinically defined as an unpleasant emotional state for which the cause is either not readily identified or perceived to be uncontrollable or unavoidable, whereas fear is clinically defined as an emotional and physiological response to a recognized external threat. The umbrella term 'anxiety disorder' refers to a number of specific disorders that include fears (phobias) and ...
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Neurodegeneration
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately result in their cell death, death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, Tauopathy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities su ...
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