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Milislav Demerec
Milislav Demerec (January 11, 1895 – April 12, 1966) was a Croatian- American geneticist, and the director of the Department of Genetics, Carnegie Institution of Washington IW now Cold Spring Harbor Laboratory (CSHL) from 1941 to 1960, recruiting Barbara McClintock and Alfred Hershey. Demerec was born and raised in Kostajnica (then Austria-Hungary, now Croatia). He attended College of Agriculture in Križevci, graduating in 1916. He worked at Krizevci Experiment Station, and then attended the College of Agriculture in Grignon, France after World War I. He emigrated to the United States for graduate studies in 1919. In 1919 he started his PhD at Cornell University, his work was on maize genetics and was supervised by Rollins A. Emerson. He completed his PhD in 1923 and took up a research position at the Carnegie Institution of Washington's IWDepartment of Genetics, now Cold Spring Harbor Laboratory. He completed work from his PhD, showing that ten different alleles coul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hrvatska Kostajnica
Hrvatska Kostajnica (; ; ), often just Kostajnica, is a small town in central Croatia. It is located on the Una river in the Sisak-Moslavina County, south of Petrinja and Sisak and across the river from Bosanska Kostajnica in Bosnia and Herzegovina. History Middle Ages Kostajnica was first mentioned in the document by knights templar from 1240. This year is used as official birth year of this historic town. Its name is derived from the word ''kostanj'' ("chestnut"), as the nearby hills around the Una river are covered with forests of chestnut trees. Time of the first settlement is unknown, but town lies on very important Roman roads that were used for transporting salt and cotton. Since Roman roads were merged in the vicinity of the city it is believed that settlement dates much earlier than the first written document known today. Position of town is very similar to the town from old Roman documents known as “Oeneum”. Five Roman milestones were located in the city dating ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Hollaender
Alexander Hollaender (9 December 1898 – 6 December 1986) was one of the world's leading researchers in radiation biology and in genetic mutations. In 1983 he was given the Enrico Fermi Award by the United States Department of Energy for his contributions in founding the science of radiation biology, and for his leadership in promoting "scientific exchanges" between American scientists and scientists from developing countries. Hollaender was born in Samter, German Empire (Szamotuły, Poland), he emigrated to the US in 1921. In 1939 Hollaender published research showing that the mutations of spores of the ringworm fungus occurred in the same spectrum as the absorption spectrum of nucleic acids indicating that nucleic acids form the building blocks of genes. A young Esther M. Zimmer, who worked with Dr. Hollaender at the U. S. Public Health Service (Bethesda, MD), published with Dr. Hollaender, Eva Sansome and Milislav Demerec in this very early field of x-ray- and UV-induced mut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Esther M
Esther is the eponymous heroine of the Book of Esther. In the Achaemenid Empire, the Persian king Ahasuerus seeks a new wife after his queen, Vashti, is deposed for disobeying him. Hadassah, a Jewess who goes by the name of Esther, is chosen to fulfill this role due to her beauty. Ahasuerus' grand vizier, Haman, is offended by Esther's cousin and guardian, Mordecai, due to his refusal to prostrate himself before Haman. Consequently, Haman plots to have all the Jewish subjects of Persia killed, and convinces Ahasuerus to permit him to do so. However, Esther foils the plan by revealing Haman's eradication plans to Ahasuerus, who then has Haman executed and grants permission to the Jews to kill their enemies instead, as royal edicts (including the order for eradication issued by Haman) cannot be revoked under Persian law. Her story provides the traditional explanation for the Jewish holiday of Purim, celebrated on the date given in the story for when Haman's order was to go ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Katherine Brehme Warren
Katherine "Kitty" Brehme Warren (1909–1991) was an American geneticist and scientific editor known for her work at Cold Spring Harbor Laboratory. Early life and education Warren was born Katherine Suydam Brehme in New York City in 1909, to parents Almira and Franklin Brehme. She graduated from Barnard College in 1930 and earned a doctorate in zoology from Columbia University. She married fellow scientist Charles O. Warren in 1939. Cold Spring Harbor Laboratory Brehme was a student of Calvin Bridges and after his death the Assistant Director of Cold Spring Harbor Laboratory. Milislav Demerec pushed for Warren's appointment to complete some of Bridges's unfinished work. The project was supported by a fellowship from the Carnegie Institution of Washington and the completed work, ''The Mutants of Drosophila melanogaster'' (1944), became a classic in the field. For decades "Bridges and Brehme" served as an essential reference for geneticists and later formed the backbone of subseque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Hunt Morgan
Thomas Hunt Morgan (September 25, 1866 – December 4, 1945) was an American evolutionary biologist, geneticist, embryologist, and science author who won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity. Morgan received his Ph.D. from Johns Hopkins University in zoology in 1890 and researched embryology during his tenure at Bryn Mawr. Following the rediscovery of Mendelian inheritance in 1900, Morgan began to study the genetic characteristics of the fruit fly ''Drosophila melanogaster''. In his famous Fly Room at Columbia University's Schermerhorn Hall, Morgan demonstrated that genes are carried on chromosomes and are the mechanical basis of heredity. These discoveries formed the basis of the modern science of genetics. During his distinguished career, Morgan wrote 22 books and 370 scientific papers. As a result of his work, ''Drosophila'' became a major model organism in contemporary genetics. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Blakeslee
Albert Francis Blakeslee (November 9, 1874 – November 16, 1954) was an American botanist. He is best known for his research on the poisonous jimsonweed plant and the sexuality of fungi. He was the brother of the Far East scholar George Hubbard Blakeslee. Early life and education Albert Francis Blakeslee was born on November 9, 1874 in Geneseo, New York, to Augusta Miranda Hubbard Blakeslee and Francis Durbin Blakeslee, a Methodist minister. Blakeslee attended Wesleyan University, graduating in 1896. At Wesleyan, Blakeslee played several sports and won academic prizes in mathematics and chemistry. He received a master's degree from Harvard University in 1900 and a doctorate in 1904. He also studied at the University of Halle-Wittenberg in Germany from 1904 to 1906. ''Datura'', jimsonweed, research Blakeslee used the jimsonweed plant as a model organism for his genetic research. His experiments included using colchicine to achieve an increase in the number of chromosomes, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calvin Bridges
Calvin Blackman Bridges (January 11, 1889 – December 27, 1938) was an American scientist known for his contributions to the field of genetics. Along with Alfred Sturtevant and H.J. Muller, Bridges was part of Thomas Hunt Morgan's famous "Fly Room" at Columbia University. Early life Calvin Blackman Bridges was born in Schuyler Falls, New York in 1889 to the parents of Leonard Bridges and Charlotte Blackman. Tragically, Calvin's mother died when he was two years old, and his father died a year later, leaving the young Calvin an orphan. Bridges was subsequently taken in and raised by his grandmother. It took Bridges several years to complete high school, graduating when he was 20 years old. Despite this setback, he moved on to be an outstanding student at Columbia University in New York City, which he attended both undergraduate and postgraduate school. While taking a zoology class at Columbia, Bridges met Thomas Hunt Morgan. This started a relationship which would eventually ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the " vinegar fly" or " pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mosaicism
Mosaicism or genetic mosaicism is a condition in multicellular organisms in which a single organism possesses more than one genetic line as the result of genetic mutation. This means that various genetic lines resulted from a single fertilized egg. Genetic mosaics may often be confused with chimerism, in which two or more genotypes arise in one individual similarly to mosaicism. In chimerism, though, the two genotypes arise from the fusion of more than one fertilized zygote in the early stages of embryonic development, rather than from a mutation or chromosome loss. Genetic mosaicism can result from many different mechanisms including chromosome nondisjunction, anaphase lag, and endoreplication. Anaphase lagging is the most common way by which mosaicism arises in the preimplantation embryo. Mosaicism can also result from a mutation in one cell during development, in which case the mutation will be passed on only to its daughter cells (and will be present only in certain adul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophilidae
The Drosophilidae are a diverse, cosmopolitan family of flies, which includes species called fruit flies, although they are more accurately referred to as vinegar or pomace flies. Another distantly related family of flies, Tephritidae, are true fruit flies because they are frugivorous, and include apple maggot flies and many pests. The best known species of the Drosophilidae is ''Drosophila melanogaster'', within the genus ''Drosophila'', also called the "fruit fly." ''Drosophila melanogaster'' is used extensively for studies concerning genetics, development, physiology, ecology and behaviour. Many fundamental biological mechanisms were discovered first in ''D. melanogaster.'' The fruit fly is mostly composed of post-mitotic cells, has a very short lifespan, and shows gradual aging. As in other species, temperature influences the life history of the animal. Several genes have been identified that can be manipulated to extend the lifespan of these insects. Additionally, ''Drosoph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Delphinium
''Delphinium'' is a genus of about 300 species of annual and perennial flowering plants in the family Ranunculaceae, native throughout the Northern Hemisphere and also on the high mountains of tropical Africa. The genus was erected by Carl Linnaeus. All members of the genus ''Delphinium'' are toxic to humans and livestock. The common name larkspur is shared between perennial ''Delphinium'' species and annual species of the genus ''Consolida''. Molecular data show that ''Consolida'', as well as another segregate genus, ''Aconitella'', are both embedded in ''Delphinium''. The genus name ''Delphinium'' derives from the Ancient Greek word () which means "dolphin", a name used in ''De Materia Medica'' for some kind of larkspur. Pedanius Dioscorides said the plant got its name because of its dolphin-shaped flowers. Habitat Species with short stems and few flowers such as ''Delphinium nuttallianum'' and ''Delphinium bicolor'' appear in habitats like prairies and the sagebrush steppe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
