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Microbicides Development Programme
Microbicides Development Programme is an organisation based in London which promotes the study of microbicides for sexually transmitted diseases Microbicides for sexually transmitted diseases are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection (for example, the human immunodeficiency virus) .... Oversight The Microbicides Development Programme is funded by the Department for International Development through the Medical Research Council (UK), Medical Research Council. The organisation is coordinated MRC Clinical Trials Unit and the Imperial College London at St Mary's Hospital, London, St Mary's Hospital. The organisation was founded on 25 January 2006. PRO 2000 The MDP conducting testing of the microbicide gel PRO 2000 in sub-Saharan Africa starting in 2005. References External links

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London
London is the capital and List of urban areas in the United Kingdom, largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a major settlement for two millennia. The City of London, its ancient core and financial centre, was founded by the Roman Empire, Romans as ''Londinium'' and retains its medieval boundaries.See also: Independent city#National capitals, Independent city § National capitals The City of Westminster, to the west of the City of London, has for centuries hosted the national Government of the United Kingdom, government and Parliament of the United Kingdom, parliament. Since the 19th century, the name "London" has also referred to the metropolis around this core, historically split between the Counties of England, counties of Middlesex, Essex, Surrey, Kent, and Hertfordshire, which largely comprises Greater London ...
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Microbicides For Sexually Transmitted Diseases
Microbicides for sexually transmitted diseases are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection (for example, the human immunodeficiency virus). Microbicides are a diverse group of chemical compounds that exert their activity by a variety of different mechanisms of action. Multiple compounds are being developed and tested for their microbicidal activity in clinical trials. Microbicides can be formulated in various delivery systems including gels, creams, lotions, aerosol sprays, tablets or films (which must be used near the time of sexual intercourse) and sponges and vaginal rings (or other devices that release the active ingredient(s) over a longer period). Some of these agents are being developed for vaginal application, and for rectal use by those engaging in anal sex. Although there are many approaches to preventing sexually transmitted diseases in general (and HIV in p ...
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Department For International Development
The Department for International Development (DFID) was a department of HM Government responsible for administering foreign aid from 1997 to 2020. The goal of the department was "to promote sustainable development and eliminate world poverty". DFID was headed by the United Kingdom's Secretary of State for International Development. The position was last held between 13 February 2020 and the department's abolishment on 2 September 2020 by Anne-Marie Trevelyan. In a 2010 report by the Development Assistance Committee (DAC), DFID was described as "an international development leader in times of global crisis". The UK aid logo is often used to publicly acknowledge DFID's development programmes are funded by UK taxpayers. DFID's main programme areas of work were Education, Health, Social Services, Water Supply and Sanitation, Government and Civil Society, Economic Sector (including Infrastructure, Production Sectors and Developing Planning), Environment Protection, Research, and Hu ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequ ...
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Imperial College London
Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cultural area that included the Royal Albert Hall, Victoria & Albert Museum, Natural History Museum and royal colleges. In 1907, Imperial College was established by a royal charter, which unified the Royal College of Science, Royal School of Mines, and City and Guilds of London Institute. In 1988, the Imperial College School of Medicine was formed by merging with St Mary's Hospital Medical School. In 2004, Queen Elizabeth II opened the Imperial College Business School. Imperial focuses exclusively on science, technology, medicine, and business. The main campus is located in South Kensington, and there is an innovation campus in White City. Facilities also include teaching hospitals throughout London, and with Imperial College ...
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St Mary's Hospital, London
St Mary's Hospital is an NHS hospital in Paddington, in the City of Westminster, London, founded in 1845. Since the UK's first academic health science centre was created in 2008, it has been operated by Imperial College Healthcare NHS Trust, which also operates Charing Cross Hospital, Hammersmith Hospital, Queen Charlotte's and Chelsea Hospital and the Western Eye Hospital. Until 1988 the hospital ran St Mary's Hospital Medical School, part of the federal University of London. In 1988 it merged with Imperial College London, and then with Charing Cross and Westminster Medical School in 1997 to form Imperial College School of Medicine. In 2007 Imperial College became an independent institution when it withdrew from the University of London. History Development of the hospital The original block of St Mary's Hospital in Norfolk Place was designed by Thomas Hopper in the classical style. It first opened its doors to patients in 1851, the last of the great voluntar ...
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PRO 2000
PRO 2000 is an experimental vaginal microbicide which has been proposed as a preventive medicine for reducing the risk of contracting HIV. It has never been recommended as an effective medicine to be used for any purpose. Some clinical trials have shown that under some conditions it may provide some protection against HIV. History Endo Pharmaceuticals manufactures the drug. Efficacy Animal testing studies done on macaques have shown that PRO 2000 is effective in preventing the transmission of HIV. Other studies have given supportive evidence that the product is safe in humans and would be an appropriate candidate for testing. A phase III clinical trial The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. For drug development, the clinical phase ... of 9385 women in sub-Saharan Africa showed that PRO 2000 was not effective i ...
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Sub-Saharan Africa
Sub-Saharan Africa is, geographically, the area and regions of the continent of Africa that lies south of the Sahara. These include West Africa, East Africa, Central Africa, and Southern Africa. Geopolitically, in addition to the African countries and territories that are situated fully in that specified region, the term may also include polities that only have part of their territory located in that region, per the definition of the United Nations (UN). This is considered a non-standardized geographical region with the number of countries included varying from 46 to 48 depending on the organization describing the region (e.g. UN, WHO, World Bank, etc.). The African Union uses a different regional breakdown, recognizing all 55 member states on the continent - grouping them into 5 distinct and standard regions. The term serves as a grouping counterpart to North Africa, which is instead grouped with the definition of MENA (i.e. Middle East–North Africa) as it is part o ...
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Microbicides
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are microbicides, while those that merely inhibit their growth are called bacteriostatic agents. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants (non-selective agents, such as bleach), which kill a wide range of microbes on non-living surfaces to prevent the spread of illness, antiseptics (which are applied to living tissue and help reduce infection during surgery), and antibiotics (which destroy microorganisms within the body ...
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Organisations Associated With Imperial College London
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, includi ...
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Organizations Established In 1996
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, in ...
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Medical And Health Organisations Based In London
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, ...
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