Microbial Hyaluronic Acid Production
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Microbial Hyaluronic Acid Production
Microbial hyaluronic acid production refers to the process by which microorganisms, such as bacteria and yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ..., are utilized in fermentation to synthesize hyaluronic acid (HA). HA is used in a wide range of medical, Cosmetic industry, cosmetic, and biological products because of its high moisture retention and viscoelasticity qualities. HA had originally been extracted from rooster comb (anatomy), combs in limited quantities. However, challenges such as low yields, high production costs, and ethical issues associated with animal-derived HA has driven the development of microbial production methods for HA. Although there are other methods for instance chemical synthesis and modification, chemoenzymatic synthesis, enzymatic synthesis; ...
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Microorganism
A microorganism, or microbe, is an organism of microscopic scale, microscopic size, which may exist in its unicellular organism, single-celled form or as a Colony (biology)#Microbial colonies, colony of cells. The possible existence of unseen microbial life was suspected from antiquity, with an early attestation in Jain literature authored in 6th-century BC India. The scientific study of microorganisms began with their observation under the microscope in the 1670s by Anton van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera, diphtheria, and anthrax. Microorganisms are extremely diverse, representing most unicellular organisms in all three domains of life: two of the three domains, Archaea and Bacteria, only contain microorganisms. The third domain, Eukaryota, includes all multicellular o ...
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