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Michael Somogyi
Dr. Michael Somogyi (March 7, 1883 – July 21, 1971) was a Hungarian-American professor of biochemistry at Washington University and the Jewish Hospital of St. Louis. He prepared the first insulin treatment given to a child with diabetes in the USA in October 1922. Somogyi later showed that excessive insulin makes diabetes unstable in the Chronic Somogyi rebound to which he gave his name. Career Michael Somogyi was born on March 7, 1883 in the village of Zsámánd in Hungary, (today Reinersdorf, part of Heiligenbrunn, Austria). He graduated in chemical engineering from the University of Budapest in 1905.Finding Aid tPhotographs from the Dr. Michael Somogyi Collection, 1912-1971 (bulk 1950s)at the Science History Institute (For full finding aid, click on 'Dr. Michael Somogyi Collection Finding Aid'.) After an additional year as an assistant in biochemistry, Somogyi went to the United States, where he eventually found a position as an assistant in biochemistry at Cornell Univer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kingdom Of Hungary
The Kingdom of Hungary was a monarchy in Central Europe that existed for nearly a millennium, from the Middle Ages into the 20th century. The Principality of Hungary emerged as a Christian kingdom upon the coronation of the first king Stephen I at Esztergom around the year 1000;Kristó Gyula – Barta János – Gergely Jenő: Magyarország története előidőktől 2000-ig (History of Hungary from the prehistory to 2000), Pannonica Kiadó, Budapest, 2002, , p. 687, pp. 37, pp. 113 ("Magyarország a 12. század második felére jelentős európai tényezővé, középhatalommá vált."/"By the 12th century Hungary became an important European factor, became a middle power.", "A Nyugat részévé vált Magyarország.../Hungary became part of the West"), pp. 616–644 his family (the Árpád dynasty) led the monarchy for 300 years. By the 12th century, the kingdom became a European middle power within the Western world. Due to the Ottoman occupation of the central and s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cornell University
Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach and make contributions in all fields of knowledge—from the classics to the sciences, and from the theoretical to the applied. These ideals, unconventional for the time, are captured in Cornell's founding principle, a popular 1868 quotation from founder Ezra Cornell: "I would found an institution where any person can find instruction in any study." Cornell is ranked among the top global universities. The university is organized into seven undergraduate colleges and seven graduate divisions at its main Ithaca campus, with each college and division defining its specific admission standards and academic programs in near autonomy. The university also administers three satellite campuses, two in New York City and one in Educatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1883 Births
Events January–March * January 4 – ''Life'' magazine is founded in Los Angeles, California, United States. * January 10 – A fire at the Newhall Hotel in Milwaukee, Wisconsin, United States, kills 73 people. * January 16 – The Pendleton Civil Service Reform Act, establishing the United States civil service, is passed. * January 19 – The first electric lighting system employing overhead wires begins service in Roselle, New Jersey, United States, installed by Thomas Edison. * February – '' The Adventures of Pinocchio'' by Carlo Collodi is first published complete in book form, in Italy. * February 15 – Tokyo Electrical Lightning Grid, predecessor of Tokyo Electrical Power ( TEPCO), one of the largest electrical grids in Asia and the world, is founded in Japan. * February 16 – The ''Ladies' Home Journal'' is published for the first time, in the United States. * February 23 – Alabama becomes the first U.S. s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dawn Phenomenon
The dawn phenomenon, sometimes called the dawn effect, is an observed increase in blood sugar (glucose) levels that takes place in the early-morning, often between 2 a.m. and 8 a.m. First described by Schmidt in 1981 as an increase of blood glucose or insulin demand occurring at dawn, this naturally occurring phenomenon is frequently seen among the general population and is clinically relevant for patients with diabetes as it can affect their medical management. In contrast to Chronic Somogyi rebound, the dawn phenomenon is not associated with nocturnal hypoglycemia. Physiology Although not yet completely understood, the dawn phenomenon is thought to be caused by an exaggeration of the normal physiologic hormonal processes that occur overnight. Overnight the human body sees increased levels of several hormones, most notably growth hormone and catecholamines, that lead to increased rates of glucose production and release from the liver. These hormones also inhibit the effe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Access (publishing)
Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre open access, barriers to copying or reuse are also reduced or removed by applying an open license for copyright. The main focus of the open access movement is "peer reviewed research literature". Historically, this has centered mainly on print-based academic journals. Whereas non-open access journals cover publishing costs through access tolls such as subscriptions, site licenses or pay-per-view charges, open-access journals are characterised by funding models which do not require the reader to pay to read the journal's contents, relying instead on author fees or on public funding, subsidies and sponsorships. Open access can be applied to all forms of published research output, including peer-reviewed and non peer-reviewed academic journal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eli Lilly & Company
Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by, and named after, Colonel Eli Lilly, a pharmaceutical chemist and veteran of the American Civil War. As of 2022, Lilly is known for its clinical depression drugs Prozac (fluoxetine) (1986) and Cymbalta (duloxetine) (2004) and its antipsychotic medication Zyprexa (olanzapine) (1996), although its primary revenue drivers are the diabetes drugs Humalog (insulin lispro) (1996) and Trulicity (dulaglutide) (2014). Lilly's achievements include being the first company to mass-produce the polio vaccine developed by Jonas Salk, and insulin. It was one of the first pharmaceutical companies to produce human insulin using recombinant DNA including Humulin ( insulin medication), Humalog (insulin lispro), and the first approved biosimilar insulin product in the US, Basaglar (ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John James Rickard Macleod
John James Rickard Macleod (6 September 1876 – 16 March 1935) was a Scottish biochemist and physiologist. He devoted his career to diverse topics in physiology and biochemistry, but was chiefly interested in carbohydrate metabolism. He is noted for his role in the discovery and isolation of insulin during his tenure as a lecturer at the University of Toronto, for which he and Frederick Banting received the 1923 Nobel prize in Physiology or Medicine. Awarding the prize to Macleod was controversial at the time, because according to Banting's version of events, Macleod's role in the discovery was negligible. It was not until decades after the events that an independent review acknowledged a far greater role than was attributed to him at first. Biography Macleod was born in Clunie, near Dunkeld in Perthshire. Soon after he was born, his father Robert Macleod, a clergyman, was transferred to Aberdeen, where John attended Aberdeen Grammar School and enrolled in the study of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Herbert Best
Charles Herbert Best (February 27, 1899 – March 31, 1978) was an American-Canadian medical scientist and one of the co-discoverers of insulin. Biography Born in West Pembroke, Maine on February 27, 1899 to Luella Fisher and Herbert Huestis Best, Canadian born physician from Nova Scotia. Best grew up in Pembroke before going to Toronto, Ontario to study medicine in 1915. Best married Margaret Hooper Mahon in Toronto in 1924 and they had two sons. One son, Henry Best was a well-regarded historian who later became president of Laurentian University in Sudbury, Ontario. Best's other son was Charles Alexander Best, a Canadian politician and geneticist. Best is the grandfather of Susan MacTavish Best. His father, Herbert Best, was a doctor in a small Maine town with a limited economy based mostly on sardine-packing. His mother, Lulu Newcomb, later Lulu Best, who sang soprano, accompanying herself on organ and piano, was in demand as a performer at funerals and weddings. By the ti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick G
Frederick may refer to: People * Frederick (given name), the name Nobility Anhalt-Harzgerode * Frederick, Prince of Anhalt-Harzgerode (1613–1670) Austria * Frederick I, Duke of Austria (Babenberg), Duke of Austria from 1195 to 1198 * Frederick II, Duke of Austria (1219–1246), last Duke of Austria from the Babenberg dynasty * Frederick the Fair (Frederick I of Austria (Habsburg), 1286–1330), Duke of Austria and King of the Romans Baden * Frederick I, Grand Duke of Baden (1826–1907), Grand Duke of Baden * Frederick II, Grand Duke of Baden (1857–1928), Grand Duke of Baden Bohemia * Frederick, Duke of Bohemia (died 1189), Duke of Olomouc and Bohemia Britain * Frederick, Prince of Wales (1707–1751), eldest son of King George II of Great Britain Brandenburg/Prussia * Frederick I, Elector of Brandenburg (1371–1440), also known as Frederick VI, Burgrave of Nuremberg * Frederick II, Elector of Brandenburg (1413–1470), Margrave of Brandenburg * Frederick William, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Adelbert Doisy
Edward Adelbert Doisy (November 13, 1893 – October 23, 1986) was an American biochemist. He received the Nobel Prize in Physiology or Medicine in 1943 with Henrik Dam for their discovery of vitamin K (K from "Koagulations-Vitamin" in German) and its chemical structure. Doisy was born in Hume, Illinois, on November 13, 1893. He completed his A.B. degree in 1914 and his M.S. degree in 1916 from the University of Illinois at Urbana-Champaign. He completed his Ph.D. in 1920 from Harvard University. In 1919 he accepted a faculty appointment in the Department of Biochemistry at Washington University in St. Louis, where he rose in rank to associate professor. In 1923, he moved to St. Louis University as professor and chairman of the new Department of Biochemistry. He served as professor and chairman of that department until he retired in 1965. Saint Louis University renamed the department the E.A. Doisy Department of Biochemistry, in his honor. More recently, the department has agai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Washington University Medical School
Washington University School of Medicine (WUSM) is the medical school of Washington University in St. Louis in St. Louis, Missouri. Founded in 1891, the School of Medicine has 1,260 students, 604 of which are pursuing a medical degree with or without a combined Doctor of Philosophy or other advanced degree. It also offers doctorate degrees in biomedical research through the Division of Biology and Biological Sciences. The School has developed large physical therapy (273 students) and occupational therapy (233 students) programs, as well as the Program in Audiology and Communication Sciences (100 students) which includes a Doctor of Audiology (Au.D.) degree and a Master of Science in Deaf Education (M.S.D.E.) degree. There are 1,772 faculty, 1,022 residents, and 765 fellows. The clinical service is provided by Washington University Physicians, a comprehensive medical and surgical practice providing treatment in more than 75 medical specialties. Washington University Physicians ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
