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Metaproscaline
Metaproscaline, or 3,4-dimethoxy-5-propoxyphenethylamine, is a lesser-known psychedelic drug. It is an analog of proscaline. Metaproscaline was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i Have Known And Loved)'', the dosage and the duration are unknown. Metaproscaline produces few to no effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of metaproscaline. See also * Substituted mescaline analogue * Proscaline * Mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological ... References Mescalines Psychedelic phenethylamines {{Psychoactive-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Mescaline Analogue
A substituted mescaline analogue, also known as a scaline and typically but not always a 4-substituted 3,5-dimethoxyphenethylamine, is an structural analog, analogue of the substituted phenethylamine, phenethylamine serotonergic psychedelic mescaline (3,4,5-trimethoxyphenethylamine). Other related compounds include the 2C (psychedelics), 2C (4-substituted 2,5-dimethoxyphenethylamine) and DOx (4-substituted 2,5-dimethoxyamphetamine) chemical compound, compounds as well as 3,4,5-trimethoxyamphetamine (TMA) and other 4-substituted 3,5-dimethoxyamphetamines (3C drugs). They are also mescaline analogues, but the 2C and DOx drugs have a third methoxy group in the 2 position instead of the 3 position while TMA is an substituted amphetamine, amphetamine rather than a phenethylamine. The pharmacology of mescaline analogues has been studied. Mescaline analogues, or 4-substituted 3,5-dimethoxyphenethylamines specifically, tend to be much less potency (pharmacology), potent than the 2C and DO ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychedelics, Dissociatives And Deliriants
Hallucinogens are a large, diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Most hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants. However, certain hallucinogens such as Fly agaric as well as other gabaergic hallucinogenics are more often considered to technically be hypnotics, therefore indicating another separate subcategory of drugs which can substantially alter visual perception. Etymology The word ''hallucinogen'' is derived from the word ''hallucination''. The term ''hallucinate'' dates back to around 1595–1605, and is derived from the Latin ''hallūcinātus'', the past participle of ''(h)allūcināri'', meaning "to wander in the mind." Characteristics Leo Hollister gave five criteria for classifying a drug as hallucinogenic.Glennon RA. Classical drugs: an introductory overview. In Lin GC and G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analog (chemistry)
A structural analog (analogue in modern traditional English; Commonwealth English), also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced with other atoms, groups, or substructures. A structural analog can be imagined to be formed, at least theoretically, from the other compound. Structural analogs are often isoelectronic. Despite a high chemical similarity, structural analogs are not necessarily functional analogs and can have very different physical, chemical, biochemical, or pharmacological properties. In drug discovery, either a large series of structural analogs of an initial lead compound are created and tested as part of a structure–activity relationship study or a database is screened for structural analogs of a lead compound. Chemical analogues of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proscaline
Proscaline (4-propoxy-3,5-DMPEA) is a psychedelic and hallucinogenic drug. It has structural properties similar to the drugs mescaline, isoproscaline, and escaline. In '' PiHKAL'', Alexander Shulgin reports that a dose of 30–60 mg produces effects lasting 8–12 hours. Chemistry Proscaline is in a class of compounds commonly known as phenethylamines, and is the 4- propoxy homolog of mescaline. The full name of the chemical is 4-propoxy-3,5-dimethoxyphenethylamine. Legality Proscaline is a Class A controlled substance in the UK. Proscaline is unscheduled and unregulated in the United States, but it could be considered an analog of a schedule I drug, mescaline, under the Federal Analog Act and thus be subject to the same control measures and penalties for possession and manufacture as a Schedule I drug. See also * Substituted phenethylamine * Allylescaline * 3C-P * Mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psyche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymethamphetamine (MDMA, commonly known as "ecstasy") to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential. In 1991 and 1997, he and his wife Ann Shulgin compiled the books '' PiHKAL'' and '' TiHKAL'' (standing for ''Phenethylamines'' and ''Tryptamines I Have Known And Loved''), from notebooks that extensively described their work and personal experiences with these two classes of psychoactive drugs. Shulgin performed seminal work into the descriptive synthesis of many of these compounds. Some of Shulgin's noteworthy discoveries include compounds of the 2C* family (such as 2C-B) and compounds o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proscaline
Proscaline (4-propoxy-3,5-DMPEA) is a psychedelic and hallucinogenic drug. It has structural properties similar to the drugs mescaline, isoproscaline, and escaline. In '' PiHKAL'', Alexander Shulgin reports that a dose of 30–60 mg produces effects lasting 8–12 hours. Chemistry Proscaline is in a class of compounds commonly known as phenethylamines, and is the 4- propoxy homolog of mescaline. The full name of the chemical is 4-propoxy-3,5-dimethoxyphenethylamine. Legality Proscaline is a Class A controlled substance in the UK. Proscaline is unscheduled and unregulated in the United States, but it could be considered an analog of a schedule I drug, mescaline, under the Federal Analog Act and thus be subject to the same control measures and penalties for possession and manufacture as a Schedule I drug. See also * Substituted phenethylamine * Allylescaline * 3C-P * Mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psyche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sources It occurs naturally in several species of cacti. It is also found in small amounts in certain members of the bean family, Fabaceae, including '' Acacia berlandieri''. However those claims concerning ''Acacia'' species have been challenged and have been unsupported in any additional analysis. History and use Peyote has been used for at least 5,700 years by Indigenous peoples of the Americas in Mexico. Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Other mescaline-containing cacti such as the San Pedro have a long history of use in South America, from Peru to Ecuador. While religious and ceremonial peyote use was widespread in the Aztec empire and nor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
