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Metabolic Control Analysis
In biochemistry, metabolic control analysis (MCA) is a mathematical framework for describing Metabolic pathway, metabolic, Cell signaling#Signaling pathways, signaling, and genetic pathways. MCA quantifies how variables, such as fluxes and Chemical species, species concentrations, depend on Network (mathematics), network parameters. In particular, it is able to describe how network-dependent properties, called control coefficients, depend on Local property, local properties called Elasticity of a function, elasticities or elasticity coefficients. MCA was originally developed to describe the control in metabolic pathways but was subsequently extended to describe signaling and Gene regulatory network, genetic networks. MCA has sometimes also been referred to as ''Metabolic Control Theory,'' but this terminology was rather strongly opposed by Henrik Kacser, one of the founders. More recent work has shown that MCA can be Isomorphism, mapped directly on to classical control theory an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Formalism (mathematics)
In the philosophy of mathematics, formalism is the view that holds that statements of mathematics and logic can be considered to be statements about the consequences of the manipulation of String (computer science), strings (alphanumeric sequences of symbols, usually as equations) using established Rule of inference, manipulation rules. A central idea of formalism "is that mathematics is not a body of propositions representing an abstract sector of reality, but is much more akin to a game, bringing with it no more commitment to an ontology of objects or properties than Ludo (board game), ludo or chess." According to formalism, mathematical statements are not "about" numbers, sets, triangles, or any other mathematical objects in the way that physical statements are about material objects. Instead, they are purely Syntax (logic), syntactic expressions—formal strings of symbols manipulated according to explicit rules without inherent meaning. These symbolic expressions only acquire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Kinetics
Chemical kinetics, also known as reaction kinetics, is the branch of physical chemistry that is concerned with understanding the rates of chemical reactions. It is different from chemical thermodynamics, which deals with the direction in which a reaction occurs but in itself tells nothing about its rate. Chemical kinetics includes investigations of how experimental conditions influence the speed of a chemical reaction and yield information about the reaction's mechanism and transition states, as well as the construction of mathematical models that also can describe the characteristics of a chemical reaction. History The pioneering work of chemical kinetics was done by German chemist Ludwig Wilhelmy in 1850. He experimentally studied the rate of inversion of sucrose and he used integrated rate law for the determination of the reaction kinetics of this reaction. His work was noticed 34 years later by Wilhelm Ostwald. In 1864, Peter Waage and Cato Guldberg published the law ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connectivity (graph Theory)
In mathematics and computer science, connectivity is one of the basic concepts of graph theory: it asks for the minimum number of elements (nodes or edges) that need to be removed to separate the remaining nodes into two or more Connected component (graph theory), isolated subgraphs. It is closely related to the theory of flow network, network flow problems. The connectivity of a graph is an important measure of its resilience as a network. Connected vertices and graphs In an undirected graph , two vertex (graph theory), vertices and are called connected if contains a Path (graph theory), path from to . Otherwise, they are called disconnected. If the two vertices are additionally connected by a path of length (that is, they are the endpoints of a single edge), the vertices are called adjacent. A Graph (discrete mathematics), graph is said to be connected if every pair of vertices in the graph is connected. This means that there is a Path (graph theory), path between every ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, energy change as new products are generated. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the Atomic nucleus, nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive Chemical element, elements where both electronic and nuclear changes can occur. The substance (or substances) initially involved in a chemical reaction are called reagent, reactants or reagents. Chemical reactions are usually characterized by a chemical change, and they yield one or more Product (c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Logical Implication
Logic is the study of correct reasoning. It includes both formal and informal logic. Formal logic is the study of deductively valid inferences or logical truths. It examines how conclusions follow from premises based on the structure of arguments alone, independent of their topic and content. Informal logic is associated with informal fallacies, critical thinking, and argumentation theory. Informal logic examines arguments expressed in natural language whereas formal logic uses formal language. When used as a countable noun, the term "a logic" refers to a specific logical formal system that articulates a proof system. Logic plays a central role in many fields, such as philosophy, mathematics, computer science, and linguistics. Logic studies arguments, which consist of a set of premises that leads to a conclusion. An example is the argument from the premises "it's Sunday" and "if it's Sunday then I don't have to work" leading to the conclusion "I don't have to work. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Summation
In mathematics, summation is the addition of a sequence of numbers, called ''addends'' or ''summands''; the result is their ''sum'' or ''total''. Beside numbers, other types of values can be summed as well: functions, vectors, matrices, polynomials and, in general, elements of any type of mathematical objects on which an operation denoted "+" is defined. Summations of infinite sequences are called series. They involve the concept of limit, and are not considered in this article. The summation of an explicit sequence is denoted as a succession of additions. For example, summation of is denoted , and results in 9, that is, . Because addition is associative and commutative, there is no need for parentheses, and the result is the same irrespective of the order of the summands. Summation of a sequence of only one summand results in the summand itself. Summation of an empty sequence (a sequence with no elements), by convention, results in 0. Very often, the elements of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Kinetics
Enzyme kinetics is the study of the rates of enzyme catalysis, enzyme-catalysed chemical reactions. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's chemical kinetics, kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a modifier (Enzyme inhibitor, inhibitor or Enzyme activator, activator) might affect the rate. An enzyme (E) is a protein molecule that serves as a biological catalyst to facilitate and accelerate a chemical reaction in the body. It does this through binding of another molecule, its Substrate (biochemistry), substrate (S), which the enzyme acts upon to form the desired product. The substrate binds to the active site of the enzyme to produce an enzyme-substrate complex ES, and is transformed into an enzyme-product complex EP and from there to product P, via a transition state ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parameter
A parameter (), generally, is any characteristic that can help in defining or classifying a particular system (meaning an event, project, object, situation, etc.). That is, a parameter is an element of a system that is useful, or critical, when identifying the system, or when evaluating its performance, status, condition, etc. ''Parameter'' has more specific meanings within various disciplines, including mathematics, computer programming, engineering, statistics, logic, linguistics, and electronic musical composition. In addition to its technical uses, there are also extended uses, especially in non-scientific contexts, where it is used to mean defining characteristics or boundaries, as in the phrases 'test parameters' or 'game play parameters'. Modelization When a system theory, system is modeled by equations, the values that describe the system are called ''parameters''. For example, in mechanics, the masses, the dimensions and shapes (for solid bodies), the densities and t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steady State
In systems theory, a system or a process is in a steady state if the variables (called state variables) which define the behavior of the system or the process are unchanging in time. In continuous time, this means that for those properties ''p'' of the system, the partial derivative with respect to time is zero and remains so: : \frac = 0 \quad \text t. In discrete time, it means that the first difference of each property is zero and remains so: : p_t-p_=0 \quad \text t. The concept of a steady state has relevance in many fields, in particular thermodynamics, economics, and engineering. If a system is in a steady state, then the recently observed behavior of the system will continue into the future. In stochastic systems, the probabilities that various states will be repeated will remain constant. For example, see ' for the derivation of the steady state. In many systems, a steady state is not achieved until some time after the system is started or initiated. This initial sit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
