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Merrill Chase
Merrill W. Chase (September 17, 1905 – January 5, 2004) was an immunologist working at Rockefeller University in New York City who is credited with discovering cell-mediated immunology in the early 1940s. While working with Dr. Karl Landsteiner, Dr. Chase discovered that white blood cells, and not antibodies alone, were important instruments of the immune system. His findings laid the groundwork for later research that discovered the role of B cells, T cells and other types of white blood cells White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign entities. White blood cells are genera .... Recognizing that other scientists were discovering multiple functions of the immune system, he established an independent Immunology laboratory at Rockefeller. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Cell
T cells (also known as T lymphocytes) are an important part of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface receptor, cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: Cytotoxic T cell, CD8+ "killer" (cytotoxic) and T helper cell, CD4+ "helper" T cells. (These are named for the presen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
B Cell
B cells, also known as B lymphocytes, are a type of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell. In addition, B cells Antigen presentation, present antigens (they are also classified as professional Antigen-presenting cell, antigen-presenting cells, APCs) and secrete cytokines. In mammals B cells Cellular differentiation, mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, which is why the ''B'' stands for ''bursa'' and not ''bone marrow'', as commonly believed. B cells, unl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is Carnegie Classification of Institutions of Higher Education, classified as a "Special Focus – Research Institution". Rockefeller is the oldest biomedical research institute in the United States. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue / Sutton Place, York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'', the ''Journal of Cell Biology'', and ''The Journal of General Physiology''. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Scienc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Landsteiner
Karl Landsteiner (; 14 June 1868 – 26 June 1943) was an Austrian-American biologist, physician, and immunologist. He emigrated with his family to New York in 1923 at the age of 55 for professional opportunities, working for the Rockefeller Institute. He had distinguished the main blood groups in 1901, having developed the modern system of classification of blood groups from his identification of the presence of agglutinins in the blood. In 1937, with Alexander S. Wiener, he identified the Rhesus factor, thus enabling physicians to transfuse blood without endangering the patient's life. With Constantin Levaditi and Erwin Popper, he discovered the polio virus in 1909. He received the Aronson Prize in 1926. In 1930, he received the Nobel Prize in Physiology or Medicine. He was posthumously awarded the Lasker Award in 1946, and has been described as the father of transfusion medicine. Early life and education He was born into a Jewish family. His father Leopold Landste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
B Cells
B cells, also known as B lymphocytes, are a type of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or plasma cell. In addition, B cells present antigens (they are also classified as professional antigen-presenting cells, APCs) and secrete cytokines. In mammals B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, which is why the ''B'' stands for ''bursa'' and not ''bone marrow'', as commonly believed. B cells, unlike the other two classes of lymphocytes, T cells and natural killer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Cells
T cells (also known as T lymphocytes) are an important part of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. (These are named for the presence of the cell surface proteins CD8 or CD4.) CD8+ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
White Blood Cells
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign entities. White blood cells are generally larger than red blood cells. They include three main subtypes: granulocytes, lymphocytes and monocytes. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system. All white blood cells have nuclei, which distinguishes them from the other blood cells, the anucleated red blood cells (RBCs) and platelets. The different white blood cells are usually classified by cell lineage ( myeloid cells or lymphoid cells). White blood cells are part of the body's immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosino ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1905 Births
As the second year of the massive Russo-Japanese War begins, more than 100,000 die in the largest world battles of that era, and the war chaos leads to the 1905 Russian Revolution against Nicholas II of Russia (Dmitri Shostakovich, Shostakovich's Symphony No. 11 (Shostakovich), 11th Symphony is subtitled ''The Year 1905'' to commemorate this) and the start of Revolution in the Kingdom of Poland (1905–07), Revolution in the Kingdom of Poland. Canada and the U.S. expand west, with the Alberta and Saskatchewan provinces and the founding of Las Vegas. 1905 is also the year in which Albert Einstein, at this time resident in Bern, publishes his four Annus Mirabilis papers, ''Annus Mirabilis'' papers in ''Annalen der Physik'' (Leipzig) (March 18, May 11, June 30 and September 27), laying the foundations for more than a century's study of theoretical physics. Events January * January 1 – In a major defeat in the Russo-Japanese War, Russian General Anatoly Stessel su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2004 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
