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Megabirnavirus Go
''Megabirnaviridae'' is a family of double-stranded RNA viruses with one genus ''Megabirnavirus'' which infects fungi. The group name derives from member's ''bi''partite ds''RNA'' genome and ''mega'' that is greater genome size (16 kbp) than families ''Birnaviridae'' (6 kbp) and ''Picobirnaviridae'' (4 kbp). The genus has five species. Diseases associated with this family include: reduced host virulence. Structure Viruses in the family ''Megabirnaviridae'' are non-enveloped, with Virus#Structure, icosahedral geometries, and T=1 symmetry. The diameter is around 50 nm. Genome The genome is composed of two double-stranded RNA segments of 7.2–8.9 kbp each and of a total length of 16.1 kbp. The genome codes for four proteins. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus Transcription (biology), transcription ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Double-stranded RNA Viruses
Double-stranded RNA viruses (dsRNA viruses) are a polyphyletic group of viruses that have double-stranded genomes made of ribonucleic acid. The double-stranded genome is used as a template by the viral RNA dependent RNA polymerase (RdRp) to transcribe a positive-strand RNA functioning as messenger RNA (mRNA) for the host cell's ribosomes, which translate it into viral proteins. The positive-strand RNA can also be replicated by the RdRp to create a new double-stranded viral genome. A distinguishing feature of the dsRNA viruses is their ability to carry out transcription of the dsRNA segments within the capsid, and the required enzymes are part of the virion structure. Double-stranded RNA viruses are classified into two phyla, '' Duplornaviricota'' and '' Pisuviricota'' (specifically class '' Duplopiviricetes''), in the kingdom '' Orthornavirae'' and realm ''Riboviria''. The two phyla do not share a common dsRNA virus ancestor, but evolved their double strands two separat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
