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Maud Menten
Maud Leonora Menten (March 20, 1879 – July 17, 1960) was a Canadian physician and chemist. As a bio-medical and medical researcher, she made significant contributions to enzyme kinetics and histochemistry, and invented a procedure that remains in use. She is primarily known for her work with Leonor Michaelis on enzyme kinetics in 1913. The paper has been translated from its written language of German into English. Maud Menten was born in Port Lambton, Ontario and studied medicine at the University of Toronto (B.A. 1904, M.B. 1907, M.D. 1911). She was among the first women in Canada to earn a medical doctorate. Since women were not allowed to participate in research in Canada at the time, Menten looked elsewhere to continue her work. In 1912, she moved to Berlin where she worked with Leonor Michaelis and co-authored their paper in ''Biochemische Zeitschrift'', demonstrating that the rate of an enzyme-catalyzed reaction is proportional to the amount of the enzyme-substrate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Port Lambton
Port Lambton is an Unincorporated area#Canada, unincorporated community in St. Clair, Ontario, St. Clair Township, Lambton County, Ontario, Canada. According to the latest census, 1084 people live within this community. In its early days, the village developed out of local transport and agricultural trade via rail and ship and evolved mainly into a summer resort community, serving seasonal residences and summer cottagers through much of its history. The village is now home to mostly permanent residences and commuters supported by larger cities and towns such as Sarnia and Wallaceburg. Every Civic Holiday weekend in August the town hosts its annual Gala Days. This community is served by two elementary schools, several churches, and a small service industry. The public school iRiverview Central Schooland the Catholic school is Sacred Heart. Until the mid-1980s Port Lambton served as a registered port of entry into Canada by utilizing a ferry crossing from nearby Roberts Landing, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UPMC Children's Hospital Of Pittsburgh
UPMC Children's Hospital of Pittsburgh (CHP), popularly known simply as Children's, is part of the University of Pittsburgh Medical Center and the only hospital in Greater Pittsburgh dedicated solely to the care of infants, children, Adolescence, teens and Youth, young adults through around age 26. UPMC Children's also sometimes treats older adults that require pediatric care. The hospital is affiliated with the University of Pittsburgh School of Medicine and features a Pennsylvania, state-verified level 1 pediatric trauma center, one of four in the state. CHP also has a rooftop helipad for emergent transport of pediatric patients. Care is provided by more than 700 board-certified pediatricians and pediatric specialists. Children's also provides primary care, specialty care, and urgent care at over 40 locations throughout the Greater Pittsburgh Region, Pittsburgh region, as well as clinical specialty services throughout western Pennsylvania at regional health care facilities. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rebecca Skloot
Rebecca L. Skloot (born September 19, 1972) is an American science writer who specializes in science and medicine.Jessica Teisch, "Floyd Skloot & Rebecca Skloot", in '' Bookmarks'', May/June 2010. Her first book, '' The Immortal Life of Henrietta Lacks'' (2010), was one of the best-selling new books of 2010, staying on ''The New York Times'' Bestseller list for over 6 years and eventually reaching #1. It was adapted into a movie by George C. Wolfe, which premiered on HBO on April 22, 2017, and starred Rose Byrne as Skloot, and Oprah Winfrey as Lacks's daughter Deborah. Early life and education Rebecca was born in Springfield, Illinois. She is the daughter of poet, novelist, and essayist Floyd Skloot and Betsy McCarthy, a professional knitter and pattern book author. Skloot said, "in the Pacific Northwest, erroots rehalf New York Jew and half Midwestern Protestant." She received her high school diploma from Metropolitan Learning Center in Portland, Oregon. After attending ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Sugar
The blood sugar level, blood sugar concentration, blood glucose level, or glycemia is the measure of glucose concentrated in the blood. The body tightly regulates blood glucose levels as a part of metabolic homeostasis. For a 70 kg (154 lb) human, approximately four grams of dissolved glucose (also called "blood glucose") is maintained in the blood plasma at all times. Glucose that is not circulating in the blood is stored in skeletal muscle and liver cells in the form of glycogen; in fasting individuals, blood glucose is maintained at a constant level by releasing just enough glucose from these glycogen stores in the liver and skeletal muscle in order to maintain homeostasis. Glucose can be transported from the intestines or liver to other tissues in the body via the bloodstream. Cellular glucose uptake is primarily regulated by insulin, a hormone produced in the pancreas. Once inside the cell, the glucose can now act as an energy source as it undergoes the pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemoglobin
Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12to 20grams of hemoglobin in every 100mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin. In mammals, hemoglobin makes up about 96% of a red blood cell's dry matter, dry weight (excluding water), and around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL of O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. The mammalian hemoglobin molecule can bind and transport up to four ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linus Pauling
Linus Carl Pauling ( ; February 28, 1901August 19, 1994) was an American chemist and peace activist. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have Nobel Prize#Multiple laureates, won more than one Nobel Prize. Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions to the theory of the chemical bond include the concept of orbital hybridisation and the first accurate scale of electronegativity, electronegativities of the elements. Pauling also wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophoresis
Electrophoresis is the motion of charged dispersed particles or dissolved charged molecules relative to a fluid under the influence of a spatially uniform electric field. As a rule, these are zwitterions with a positive or negative net charge. Electrophoresis is used in laboratories to separate macromolecules based on their charges. The technique normally applies a negative charge called cathode so anionic protein molecules move towards a positive charge called anode. Therefore, electrophoresis of positively charged particles or molecules (cations) is sometimes called cataphoresis, while electrophoresis of negatively charged particles or molecules (anions) is sometimes called anaphoresis. Electrophoresis is the basis for analytical techniques used in biochemistry and molecular biology to separate particles, molecules, or ions by size, charge, or binding affinity, either freely or through a supportive medium using a one-directional flow of electrical charge. It is use ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salmonella
''Salmonella'' is a genus of bacillus (shape), rod-shaped, (bacillus) Gram-negative bacteria of the family Enterobacteriaceae. The two known species of ''Salmonella'' are ''Salmonella enterica'' and ''Salmonella bongori''. ''S. enterica'' is the type species and is further divided into six subspecies that include over 2,650 serotypes. ''Salmonella'' was named after Daniel Elmer Salmon (1850–1914), an American veterinary surgeon. ''Salmonella'' species are non-Endospore, spore-forming, predominantly motility, motile enterobacteriaceae, enterobacteria with cell diameters between about 0.7 and 1.5 micrometre, μm, lengths from 2 to 5 μm, and peritrichous flagella (all around the cell body, allowing them to move). They are chemotrophs, obtaining their energy from Redox, oxidation and reduction reactions, using organic sources. They are also facultative aerobic organism, facultative anaerobes, capable of generating adenosine triphosphate with oxygen ("aerobically") ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaline Phosphatase
The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase, also abbreviated PhoA) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme is found across a multitude of organisms, prokaryotes and eukaryotes alike, with the same general function, but in different structural forms suitable to the environment they function in. Alkaline phosphatase is found in the periplasmic space of '' E. coli'' bacteria. This enzyme is heat stable and has its maximum activity at high pH. In humans, it is found in many forms depending on its origin within the body – it plays an integral role in metabolism within the liver and development within the skeleton. Due to its widespread prevalence in these areas, its concentration in the bloodstream is used by diagnosticians as a biomarker in helping determine diagnoses such as hepatitis or osteomalacia. The level of alkaline phosphatase in the blood is checked through the ALP test, which is often par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michaelis–Menten Kinetics
In biochemistry, Michaelis–Menten kinetics, named after Leonor Michaelis and Maud Menten, is the simplest case of enzyme kinetics, applied to enzyme-catalysed reactions involving the transformation of one substrate into one product. It takes the form of a differential equation describing the reaction rate v (rate of formation of product (biology), product P, with concentration p) as a function of a, the concentration of the Enzyme substrate (biology), substrate A (using the symbols recommended by the IUBMB). Its formula is given by the Michaelis–Menten equation: : v = \frac = \frac V, which is often written as V_\max, represents the limiting rate approached by the system at saturating substrate concentration for a given enzyme concentration. The Michaelis constant K_\mathrm has units of concentration, and for a given reaction is equal to the concentration of substrate at which the reaction rate is half of V. Biochemical reactions involving a single substrate are often ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Victor Henri
Victor Henri (6 June 1872 – 21 June 1940) was a French-Russian Physical chemistry, physical chemist and physiologist. He was born in Marseilles as a son of Russian parents. He is known mainly as an early pioneer in enzyme kinetics. He published more than 500 papers in a variety of disciplines including biochemistry, physical chemistry, psychology, and physiology. Aleksey Krylov was his half-brother. Life Victor Henri's parents were Aleksandra Viktorovna Lyapunova and Nikolay Alexandrovich Krylov, who were not married. His father was married to his mother's sister, Sofiya Viktorovna. At that time, an illegitimate child had no rights if born in Russia, but France was different: if born in France one would be a French citizen. So his parents traveled to Marseilles for his birth. After Victor Henri was born there, Krylov and his legitimate wife then adopted him, and took him back to Saint Petersburg, where he lived with his father, his biological mother, and his adoptive mother. He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crile (crater)
Crile is a tiny lunar impact crater. It is roughly circular and cup-shaped, with interior walls that slope down to the midpoint. The crater lies in the Palus Somni, between the Mare Crisium to the east and Mare Tranquillitatis to the west. This formation was previously designated Proclus F before being renamed by the IAU in 1976. Proclus itself is located to the north-northeast. The crater was named for American surgeon George Washington Crile. Gazetteer of Planetary Nomenclature, International Astronomical Union
The International Astronomical Union (IAU; , UAI) is an international non-governmental organization (INGO) with the objective of advancing astro ...
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