Mart Saarma
Mart Saarma (born 29 June 1949 in Tartu) is an Estonian molecular biologist, member of the Estonian Academy of Sciences. Biography He is the third child of the professors of the medical department of Tartu University – Jüri Saarma (psychiatrist) and Valve Erika Saarma (gastroenterologist). He has worked both in Moscow, Helsinki and Basel. His main research is dedicated to plant viruses and virus resistance, the development of the nervous system and the mechanisms of the death of nerve cells and the possibilities to use nerve growth factors Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was on ... in case of treating neurodegenerative diseases. References 1949 births Estonian biochemists Molecular biologists Scientists from Tartu Living people Recipients of the Order of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tartu
Tartu is the second largest city in Estonia after the Northern European country's political and financial capital, Tallinn. Tartu has a population of 91,407 (as of 2021). It is southeast of Tallinn and 245 kilometres (152 miles) northeast of Riga, Latvia. Tartu lies on the Emajõgi river, which connects the two largest lakes in Estonia, Lake Võrtsjärv and Lake Peipus. From the 13th century until the end of the 19th century, Tartu was known in most of the world by variants of its historical name Dorpat. Tartu, the largest urban centre of southern Estonia, is often considered the "intellectual capital city" of the country, especially as it is home to the nation's oldest and most renowned university, the University of Tartu (founded in 1632). Tartu also houses the Supreme Court of Estonia, the Ministry of Education and Research, the Estonian National Museum, and the oldest Estonian-language theatre, Vanemuine. It is also the birthplace of the Estonian Song Festiva ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Estonian Academy Of Sciences
Founded in 1938, the Estonian Academy of Sciences ( et, Eesti Teaduste Akadeemia) is Estonia's national academy of science in Tallinn. As with other national academies, it is an independent group of well-known scientists whose stated aim is to promote research and development, encourage international scientific cooperation, and disseminate knowledge to the public.Academy web page at the Estonian Academy of Sciences. Accessed on line September 12, 2007. As of March 2017, it had 77 full members and 20 foreign members. Since 15 October 2014, the president of the Academy is the mathematician Tarmo Soomere.Facts of history web pa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jüri Saarma
Jüri is a small borough ( et, alevik) in Harju County, northern Estonia. It is located southeast of the capital Tallinn, by the Tallinn–Tartu road (E263), directly after the intersection with Tallinn Ring Road (nr. 11). Jüri is the administrative centre of Rae Parish. Jüri has a population of 3,426 as of 1 January 2012. In 2011, Jüri was the center of population of Estonia. Jüri has grown out of two parts: the centre of Sommerling kolkhoz (former Rosenhagen Manor) in the west and construction industry base with a residential area (former Jüri church and village) in the east. In the middle there is a protected Lehmja oak grove. In the 1630s the Rosenhagen Manor (Lehmja since 1917) was established; nowadays the site is located in western Jüri. Today, though the wooden main building has been destroyed, several side buildings such as the workers house have remained. The earlier Jürgens (Jüri) church was probably located in Karla in 1401. The current church in Jüri w ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nerve Growth Factors
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was one of the first to be described. Since it was first isolated by Nobel Laureates Rita Levi-Montalcini and Stanley Cohen in 1956, numerous biological processes involving NGF have been identified, two of them being the survival of pancreatic beta cells and the regulation of the immune system. Structure NGF is initially in a 7S, 130-kDa complex of 3 proteins – Alpha-NGF, Beta-NGF, and Gamma-NGF (2:1:2 ratio) when expressed. This form of NGF is also referred to as proNGF (NGF precursor). The gamma subunit of this complex acts as a serine protease, and cleaves the N-terminal of the beta subunit, thereby activating the protein into functional NGF. The term ''nerve growth factor'' usually refers to the 2.5S, 26-kDa beta subunit of the protein ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neurodegenerative Diseases
A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1949 Births
Events January * January 1 – A United Nations-sponsored ceasefire brings an end to the Indo-Pakistani War of 1947. The war results in a stalemate and the division of Kashmir, which still continues as of 2022. * January 2 – Luis Muñoz Marín becomes the first democratically elected Governor of Puerto Rico. * January 11 – The first "networked" television broadcasts take place, as KDKA-TV in Pittsburgh, Pennsylvania goes on the air, connecting east coast and mid-west programming in the United States. * January 16 – Şemsettin Günaltay forms the new government of Turkey. It is the 18th government, last One-party state, single party government of the Republican People's Party. * January 17 – The first Volkswagen Beetle, VW Type 1 to arrive in the United States, a 1948 model, is brought to New York City, New York by Dutch businessman Ben Pon Sr., Ben Pon. Unable to interest dealers or importers in the Volkswagen, Pon sells the sample car to pay his ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Estonian Biochemists
Estonian may refer to: * Something of, from, or related to Estonia, a country in the Baltic region in northern Europe * Estonians, people from Estonia, or of Estonian descent * Estonian language Estonian ( ) is a Finnic language, written in the Latin script. It is the official language of Estonia and one of the official languages of the European Union, spoken natively by about 1.1 million people; 922,000 people in Estonia and 160,0 ... * Estonian cuisine * Estonian culture See also * * Estonia (other) * Languages of Estonia * List of Estonians {{Disambiguation Language and nationality disambiguation pages ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Biologists
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Rosa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Scientists From Tartu
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The rol ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |