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Marion Leboyer
Marion Leboyer (born 1957) is a French psychiatrist, university professor and hospital practitioner at the Paris-Est Créteil University (UPEC). Biography After completing her medical studies at Paris Descartes University, a master's degree and a PhD in science at Pierre and Marie Curie University in Paris, and being appointed intern at the Paris hospitals in 1981, she was head of clinic at La Pitié-Salpêtrière Hospital from 1989 to 1994. From 2002 to 2007, she was head of the sectorized psychiatry department at Albert Chenevier Hospital and of the psychiatry department at Henri Mondor Hospital in 2002 before being appointed head of the psychiatry division there. Since 2019, she is the medical director of the university hospital department Innovation en santé Mentale, Psychiatrie et AddiCTologie du Grand-Paris-Sud (DMU IMPACT) within Centre hospitalier universitaire Henri-Mondor (AP-HP) and of the Fédération hospitalo-universitaire de médecine de précision en psychiat ...
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Brackets
A bracket is either of two tall fore- or back-facing punctuation marks commonly used to isolate a segment of text or data from its surroundings. Typically deployed in symmetric pairs, an individual bracket may be identified as a 'left' or 'right' bracket or, alternatively, an "opening bracket" or "closing bracket", respectively, depending on the directionality of the context. Specific forms of the mark include parentheses (also called "rounded brackets"), square brackets, curly brackets (also called 'braces'), and angle brackets (also called 'chevrons'), as well as various less common pairs of symbols. As well as signifying the overall class of punctuation, the word "bracket" is commonly used to refer to a specific form of bracket, which varies from region to region. In most English-speaking countries, an unqualified word "bracket" refers to the parenthesis (round bracket); in the United States, the square bracket. Various forms of brackets are used in mathematics, with ...
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Bipolar Disorder
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy or irritable, and they often make impulsive decisions with little regard for the consequences. There is usually also a reduced need for sleep during manic phases. During periods of depression, the individual may experience crying and have a negative outlook on life and poor eye contact with others. The risk of suicide is high; over a period of 20 years, 6% of those with bipolar disorder died by suicide, while 30–40% engaged in self-harm. Other mental health issues, such as anxiety disorders and substance use disorders, are commonly associated with bipolar disorder. While the causes of t ...
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Monoamines
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). Examples are dopamine, norepinephrine and serotonin. All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, and tryptophan by the action of aromatic amino acid decarboxylase enzymes. They are deactivated in the body by the enzymes known as monoamine oxidases which clip off the amine group. Monoaminergic systems, i.e., the networks of neurons that use monoamine neurotransmitters, are involved in the regulation of processes such as emotion, arousal, and certain types of memory. It has also been found that monoamine neurotransmitters play an important role in the secretion and production of neurotrophin-3 by astrocytes, a chemical which maintains neuron integrity and provides neurons with trophic support. Drugs used to increase or reduce the effect of monoamine neurotransmitters are ...
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Autism
The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulties in social interaction, verbal and nonverbal communication, and the presence of repetitive behavior and restricted interests. Other common signs include unusual responses to sensory stimuli. Autism is generally understood as a '' spectrum disorder'', which means that it can manifest differently in each person: any given autistic individual is likely to show some, but not all, of the characteristics associated with it, and the person may exhibit them to varying degrees. Some autistic people remain nonspeaking over the course of their lifespan, while others have relatively unimpaired spoken language. There is large variation in the level of support people require, and the same person may present differently at varying times. Historical ...
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Genetic Mutations
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication ( translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source ...
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Clarivate
Clarivate Plc is a British-American publicly traded analytics company that operates a collection of subscription-based services, in the areas of bibliometrics and scientometrics; business / market intelligence, and competitive profiling for pharmacy and biotech, patents, and regulatory compliance; trademark protection, and domain and brand protection. In the academy and the scientific community, Clarivate is known for being the company which calculates the impact factor, using data from its Web of Science product family, that also includes services/applications such as Publons, EndNote, EndNote Click, and ScholarOne. Its other product families are Cortellis, DRG, CPA Global, Derwent, MarkMonitor, CompuMark, and Darts-ip, and also the various ProQuest products and services. Clarivate was formed in 2016, following the acquisition of Thomson Reuters' Intellectual Property and Science Business by Onex Corporation and Baring Private Equity Asia. Clarivate has been growing fast by ...
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H-index
The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winning the Nobel Prize, being accepted for research fellowships and holding positions at top universities. The index is based on the set of the scientist's most cited papers and the number of citations that they have received in other publications. The index has more recently been applied to the productivity and impact of a scholarly journal as well as a group of scientists, such as a department or university or country. The index was suggested in 2005 by Jorge E. Hirsch, a physicist at UC San Diego, as a tool for determining theoretical physicists' relative quality and is sometimes called the Hirsch index or Hirsch number. Definition and purpose The ''h''-index is defined as the maximum value of ''h'' such that the given author/jo ...
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French Academy Of Sciences
The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at the forefront of scientific developments in Europe in the 17th and 18th centuries, and is one of the earliest Academies of Sciences. Currently headed by Patrick Flandrin (President of the Academy), it is one of the five Academies of the Institut de France. History The Academy of Sciences traces its origin to Colbert's plan to create a general academy. He chose a small group of scholars who met on 22 December 1666 in the King's library, near the present-day Bibliothèque Nationals, and thereafter held twice-weekly working meetings there in the two rooms assigned to the group. The first 30 years of the Academy's existence were relatively informal, since no statutes had as yet been laid down for the institution. In contrast to its Brit ...
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European College Of Neuropsychopharmacology
The European College of Neuropsychopharmacology (ECNP) is a pan-European, non-profit scientific association that serves as a platform to exchange and promote research in the field of neuropsychopharmacology. The ECNP “is committed to ensuring that advances in the understanding of brain function and human behaviour are translated into better treatments and enhanced public health”. The ECNP organises a number of activities to achieve this aim, such as a yearly congress, workshops, seminars, New Frontiers Meetings, publications, awards, supported talks and much more. History In 1984 representatives of neuropsychopharmacological societies from across Europe suggested there might be room for a European structure. A meeting to discuss this plan further was held in Copenhagen in May 1985. It was decided that a European College of Neuropsychopharmacology would be founded. A Working Group was formed to plan of the association’s inaugural scientific congress. This congress was held ...
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International Society For Bipolar Disorders
The International Society for Bipolar Disorders (ISBD) is a nonprofit organization based in Pittsburgh, Pennsylvania, where it was founded June 17, 1999. The society focuses on research and education in bipolar disorders. The society has a membership consisting of mental health professionals and patients and their family members representing 50 countries. The mission of the society is to advance the treatment of all aspects of bipolar disorder, thereby improving patient outcomes and quality of life, through fostering international collaboration in education and research. The society hosts biennial professional meetings and offers educational programs. The official journal of the society is ''Bipolar Disorders'' and a subscription is included with membership. History The ISBD was founded at the 3rd International Conference on Bipolar Disorder, in Pittsburgh, Pennsylvania, in June 1999 by David J. Kupfer and Thomas Detre (University of Pittsburgh Medical Center). In September 1999, ...
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Mogens Schou
Mogens Schou (24 November 1918 – 29 September 2005) was a Danish psychiatrist whose research into lithium led to its utilization as a treatment for bipolar disorder. Early years Schou was born in Copenhagen, Denmark, on 24 November 1918. His father was a psychiatrist and medical director of a large mental hospital. Schou chose to study medicine with a specific view to doing research on manic-depressive illness (now more commonly referred to as bipolar disorder). He graduated with a degree in medicine from the University of Copenhagen in 1944. After his training in clinical psychiatry he also studied experimental biology. Research Schou's research interests focused on therapeutic uses of lithium for patients with mood disorders. The psychopharmacological era began in earnest in 1949, with an article published by John Cade about the observed antimanic action of lithium in Australia. Intrigued by these findings Schou, who in the meantime had joined the Psychiatric Resear ...
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Jean Bernard (physician)
Jean Bernard (26 May 1907 in Paris – 17 April 2006 in Paris) was a French physician and haematologist. He was professor of haematology and director of the Institute for Leukaemia at the University of Paris. After graduating in medicine in Paris in 1926 he commenced his laboratory training with the bacteriologist Gaston Ramon at the Pasteur Institute in 1929. In 1932 Bernard gave the first description of the use of high dosage radiotherapy in the treatment of Hodgkin's disease. Bernard's research has ranged from the demonstration of neoplastic nature of leukaemia (1933–1937) to the formulation of methods of treatment. Bernard gave his name to Bernard's syndrome and Bernard–Soulier syndrome. In all, Bernard published 14 textbooks and monographs on haematolog During the German occupation of France, Bernard was active in the French Resistance In 1973, he became a member of the Académie Nationale de Médecine; he was elected at the Académie française on 18 March 1976. In ...
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