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Maribel Rios
Maribel Rios is a neuroscientist originally from San Juan, Puerto Rico. She received a Bachelor of Arts in neuroscience from Boston University, followed by a Doctor of Philosophy in Cell, Molecular, and Developmental Biology from the Sackler School at Tufts University. Rios continued her studies by attending the Whitehead Institute at the Massachusetts Institute of Technology, where she completed her post-doctoral training in genetics. Following her education, she returned to Tufts where she serves as a professor of neuroscience. Early life and education Maribel Rios grew up in San Juan, Puerto Rico and lived there until she was 18 years old. Her father was the first one in his immediate family to go to college. He was able to do this through the G.I. Bill because of his service in the Korean War. From kindergarten to high school, she attended Academia Santa Monica in Santurce, Puerto Rico. Rios moved from Puerto Rico to Boston where she attended Boston University as a psyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Juan, Puerto Rico
San Juan ( , ; Spanish for "Saint John the Baptist, John") is the capital city and most populous Municipalities of Puerto Rico, municipality in the Commonwealth (U.S. insular area), Commonwealth of Puerto Rico, an unincorporated territory of the United States. As of the United States Census Bureau, 2020 census, it is the List of United States cities by population, 57th-most populous city under the jurisdiction of the United States, with a population of 342,259. San Juan was founded by Spanish Empire, Spanish colonists in 1521, who called it Ciudad de Puerto Rico (Spanish for "Rich Port City"). Puerto Rico's capital is the second oldest European-established capital city in the Americas, after Santo Domingo, in the Dominican Republic, founded in 1496, and is the List of North American settlements by year of foundation, oldest European-established city under United States of America, United States sovereignty. Several historical buildings are located in the historic district of Old S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotrophin
Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death – allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to ''form'' neurons. Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis. Terminology According to the United States National Library of Medicine's medical su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tufts University Faculty
Tufts University is a private research university in Medford and Somerville, Massachusetts, United States, with additional facilities in Boston and Grafton, as well as Talloires, France. Tufts also has several Doctor of Physical Therapy programs located in Boston, Phoenix and Seattle. It was founded in 1852 as Tufts College by Christian universalists who sought to provide a nonsectarian institution of higher learning. Tufts remained a small liberal arts college until the 1970s, when it transformed into a large research university offering doctorates in several disciplines. The corporate name of the university is "Trustees of Tufts College". Tufts offers over 90 undergraduate and 160 graduate programs across ten schools in the greater Boston area and Talloires, France.Bylaws of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tufts University Alumni
Tufts University is a private research university in Medford and Somerville, Massachusetts, United States, with additional facilities in Boston and Grafton, as well as Talloires, France. Tufts also has several Doctor of Physical Therapy programs located in Boston, Phoenix and Seattle. It was founded in 1852 as Tufts College by Christian universalists who sought to provide a nonsectarian institution of higher learning. Tufts remained a small liberal arts college until the 1970s, when it transformed into a large research university offering doctorates in several disciplines. The corporate name of the university is "Trustees of Tufts College". Tufts offers over 90 undergraduate and 160 graduate programs across ten schools in the greater Boston area and Talloires, France.Bylaws of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gabapentin
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat neuropathic pain and also for partial seizures of epilepsy. It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. It is moderately effective: about 30–40% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a meaningful benefit. Gabapentin, like other gabapentinoid drugs, acts by decreasing activity of the α2δ-1 protein, coded by the CACNA2D1 gene, first known as an auxiliary subunit of voltage gated calcium channels. However, see Pharmacodynamics, below. By binding to α2δ-1, gabapentin reduces the release of excitatory neurotransmitters (primarily glutamate) and as a result, reduces excess excitation of neuronal networks in the spinal cord and brain. Sleepiness and dizziness are the most common side effects. Serious side effects in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BDNF
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein found in the and the periphery. that, in humans, is encoded by the ''BDNF'' gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found in the brain and the periphery. BDNF was first isolated from a pig brain in 1982 by Yves-Alain Barde and Hans Thoenen. BDNF activates the TrkB tyrosine kinase receptor. Function BDNF acts on certain neurons of the central nervous system and the peripheral nervous system expressing TrkB, helping to support survival of existing neurons, and encouraging growth and Cellular differentiation, differentiation of new neurons and synapses. In the brain it is active in the hippocampus, Cerebral cortex, cortex, and basal forebrain areas vital to learning, memory, and higher thinking. BDNF is also expressed in the retina, kidneys, pros ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tropomyosin Receptor Kinase B
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the ''NTRK2'' gene. TrkB is a receptor for brain-derived neurotrophic factor (BDNF). The standard pronunciation for this protein is "track bee". Function Tropomyosin receptor kinase B is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The neurotrophins that activate TrkB are: BDNF (Brain Derived Neurotrophic Factor), neurotrophin-4 (NT-4), and neurotrophin-3 (NT-3). As such, TrkB mediates the multiple effects of these neurotrophic factors, which includes neuronal differentiation and survival. Research has shown that activation of the TrkB receptor can lead to down regulation of the KCC2 chloride transporter in cells of the CNS. In additio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain-derived Neurotrophic Factor
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein found in the and the periphery. that, in humans, is encoded by the ''BDNF'' gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found in the brain and the periphery. BDNF was first isolated from a pig brain in 1982 by Yves-Alain Barde and Hans Thoenen. BDNF activates the TrkB tyrosine kinase receptor. Function BDNF acts on certain neurons of the central nervous system and the peripheral nervous system expressing TrkB, helping to support survival of existing neurons, and encouraging growth and differentiation of new neurons and synapses. In the brain it is active in the hippocampus, cortex, and basal forebrain areas vital to learning, memory, and higher thinking. BDNF is also expressed in the retina, kidneys, prostate, motor neurons, and skeletal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston University
Boston University (BU) is a Private university, private research university in Boston, Massachusetts, United States. BU was founded in 1839 by a group of Boston Methodism, Methodists with its original campus in Newbury (town), Vermont, Newbury, Vermont. It was chartered in Boston in 1869. The university is a member of the Association of American Universities and the Boston Consortium for Higher Education. The university has nearly 38,000 students and more than 4,000 faculty members and is one of Boston's largest employers. It offers bachelor's degrees, master's degrees, doctorates, and medical, dental, business, and law degrees through 17 schools and colleges on three urban campuses. The university is nonsectarian, though it retains its historical affiliation with the United Methodist Church. The main campus is situated along the Charles River in Boston's Fenway–Kenmore and Allston, Massachusetts, Allston neighborhoods, while the Boston University Medical Campus is locate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Santurce, San Juan, Puerto Rico
Santurce (, meaning Saint George from Basque language, Basque ''Santurtzi'') is the largest and most populated Barrios of San Juan, Puerto Rico, barrio of the Municipalities of Puerto Rico, municipality of San Juan, Puerto Rico, San Juan, the capital city of Puerto Rico. With a population of 69,469 in 2020, Santurce is also one of the most population density, densely populated areas of the Geography of Puerto Rico, main island of Puerto Rico (13,257.4 persons per square mile (5,178.6/km2)) with a population larger than most municipalities of the territory. Founded as San Mateo de Cangrejos in the 1760, Santurce officially became part of the municipality of San Juan in 1863. From its original settlement, its history has been marked by diverse waves of immigration, particularly of Afro–Puerto Ricans, Afro-Puerto Rican, Chinese immigration to Puerto Rico, Chinese, History of the Jews in Puerto Rico, Jewish and Dominican Republic immigration to Puerto Rico, Dominican communities who ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
