Marcelle Lapicque
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Marcelle Lapicque
Marcelle de Heredia Lapicque (1873 – 1960) was a French neurophysiologist known for her research on nerve impulses (chronaxie) and the effects of poisons, especially strychnine, on chronaxie. She was in charge of the Laboratoire des Hautes-Études General Physiology laboratory until her death. Marcelle Lapicque, though overshadowed in histories of science by her husband, Louis Lapicque, was an influential scientist in her own right, publishing many papers as sole author and holding a membership to the Société de Biologie The Société de biologie is a learned society founded in Paris in 1848. The society was conceived during the French Revolution of 1848. The members of the society held regular meetings and published the proceedings in a new scientific journal. Th .... Louis Lapicque "insisted on the importance of his wife as equal co-worker in all his research".. She was the daughter of French politician Severiano de Heredia. References French neuroscientists Fr ...
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Neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated by electrophysiology—the electrical recording of neural activity ranging from the molar (the electroencephalogram, EEG) to the cellular (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field potentials. However, since the neurone is an electrochemical machine, it is difficult to isolate electrical events from the metabolic and molecular processes that cause them. Thus, neurophysiologists currently utilise tools from chemistry (calcium imaging), physics (functional magnetic resonance imaging, fMRI), and molecular biology (site directed mutations) to examine brain activity. The word originates from the Greek word meaning "nerve" and ...
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