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Mansukh Wani
Mansukh C. Wani, (died 2020), was a principal scientist (emeritus) at the Research Triangle Institute in North Carolina. He was co-discoverer of Taxol and camptothecin, two anti-cancer drugs considered standard in the treatment to fight ovarian, breast, lung and colon cancers. In 2000, Wani received an award for applied research in medicine, the Charles F. Kettering Prize, from the General Motors Cancer Research Foundation. Wani was born in Nandurbar, Maharashtra, India. He attended the University of Bombay, receiving a bachelor's degree in 1947 (in chemistry) and a master's in 1950 (in organic chemistry). He moved to the United States in 1958, and received his PhD from Indiana University Bloomington in 1962, when he joined Research Triangle Institute. He used to live in Durham, North Carolina Durham ( ) is a city in the U.S. state of North Carolina and the county seat of Durham County, North Carolina, Durham County. Small portions of the city limits extend into Orange Count ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monroe Eliot Wall
Monroe Eliot Wall (1916 – July 6, 2002) was an American chemist, who co-discovered, with Mansukh C. Wani, paclitaxel and camptothecin, two anti-cancer drugs considered standard in the treatment to fight ovarian, breast, lung and colon cancers. On May 27, 1987, Wall received an honorary doctorate from the faculty of pharmacy at Uppsala University, Sweden. Wall was born in Newark, New Jersey, in 1916. He completed his BS, MS, and PhD at Rutgers University. He joined the United States Department of Agriculture (USDA) in 1941 and worked at the USDA until 1960. That year, he started a research group at RTI International Research Triangle Institute, operating as RTI International, is a nonprofit organization headquartered in the Research Triangle Park in North Carolina, USA. RTI provides research and technical services. It was founded in 1958 with $500,000 in fu ..., where he remained for the duration of his career. References External linksMonroe E. Wall, National Cancer I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
General Motors Corporation
General Motors Company (GM) is an American multinational automotive manufacturing company headquartered in Detroit, Michigan, United States. The company is most known for owning and manufacturing four automobile brands: Chevrolet, Buick, GMC, and Cadillac, each a separate division of GM. By total sales, it has continuously been the largest automaker in the United States, and was the largest in the world for 77 years before losing the top spot to Toyota in 2008. General Motors operates manufacturing plants in eight countries. In addition to its four core brands, GM also holds interests in Chinese brands Baojun and Wuling via SAIC-GM-Wuling Automobile. GM further owns a namesake defense vehicles division which produces military vehicles for the United States government and military, the vehicle safety, security, and information services provider OnStar, the auto parts company ACDelco, and a namesake financial lending service. The company originated as a holding company f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientists From Maharashtra
A scientist is a person who researches to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales ( 624–545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. History The roles of "scientists", and their predecessors before the emergence of modern scientific disciplines, have evolved considerably over time. Scientists of different eras (and before them, natural philosophers, mathematicians, natur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indian Organic Chemists
Indian or Indians may refer to: Associated with India * of or related to India ** Indian people ** Indian diaspora ** Languages of India ** Indian English, a dialect of the English language ** Indian cuisine Associated with indigenous peoples of the Americas * Indigenous peoples of the Americas ** First Nations in Canada ** Native Americans in the United States ** Indigenous peoples of the Caribbean ** Indigenous languages of the Americas Places * Indian, West Virginia, U.S. * The Indians, an archipelago of islets in the British Virgin Islands Arts and entertainment Film * ''Indian'' (film series), a Tamil-language film series ** ''Indian'' (1996 film) * ''Indian'' (2001 film), a Hindi-language film Music * Indians (musician), Danish singer Søren Løkke Juul * "The Indian", an unreleased song by Basshunter * "Indian" (song), by Sturm und Drang, 2007 * "Indians" (song), by Anthrax, 1987 * Indians, a song by Gojira from the 2003 album '' The Link'' Other uses i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American People Of Indian Descent
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2020 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing
A year is a unit of time based on how long it takes the Earth to orbit the Sun. In scientific use, the tropical year (approximately 365 solar days, 5 hours, 48 minutes, 45 seconds) and the sidereal year (about 20 minutes longer) are more exact. The modern calendar year, as reckoned according to the Gregorian calendar, approximates the tropical year by using a system of leap years. The term 'year' is also used to indicate other periods of roughly similar duration, such as the lunar year (a roughly 354-day cycle of twelve of the Moon's phasessee lunar calendar), as well as periods loosely associated with the calendar or astronomical year, such as the seasonal year, the fiscal year, the academic year, etc. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by changes in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Durham, North Carolina
Durham ( ) is a city in the U.S. state of North Carolina and the county seat of Durham County, North Carolina, Durham County. Small portions of the city limits extend into Orange County, North Carolina, Orange County and Wake County, North Carolina, Wake County. With a population of 283,506 in the 2020 United States census, 2020 census, Durham is the List of municipalities in North Carolina, fourth-most populous city in North Carolina and the List of United States cities by population, 70th-most populous city in the United States. The city is located in the east-central part of the Piedmont (United States), Piedmont region along the Eno River. Durham is the core of the four-county Durham–Chapel Hill, North Carolina, Chapel Hill metropolitan area, which had an estimated population of 608,879 in 2023. The Office of Management and Budget also includes Durham as a part of the Raleigh–Durham–Cary, NC Combined Statistical Area, commonly known as the Research Triangle, which had an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles F
Charles is a masculine given name predominantly found in English language, English and French language, French speaking countries. It is from the French form ''Charles'' of the Proto-Germanic, Proto-Germanic name (in runic alphabet) or ''*karilaz'' (in Latin alphabet), whose meaning was "free man". The Old English descendant of this word was ''Churl, Ċearl'' or ''Ċeorl'', as the name of King Cearl of Mercia, that disappeared after the Norman conquest of England. The name was notably borne by Charlemagne (Charles the Great), and was at the time Latinisation of names, Latinized as ''Karolus'' (as in ''Vita Karoli Magni''), later also as ''Carolus (other), Carolus''. Etymology The name's etymology is a Common Germanic noun ''*karilaz'' meaning "free man", which survives in English as wikt:churl, churl (< Old English ''ċeorl''), which developed its deprecating sense in the Middle English period. Some Germanic languages, for example Dutch language, Dutch and German ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bombay
University of Mumbai is a public university, public List of largest universities and university networks by enrollment, state university in Mumbai. It is one of the List of largest universities and university networks by enrollment, largest university systems in the world with over 549,000 students on its campuses and affiliated colleges. , the university had 711 affiliated colleges. It was established in 1857 following Wood's despatch, a dispatch from Charles Wood, 1st Viscount Halifax, Sir Charles Wood, President of the Board of Control, to Governor-General of India, Governor-General James Broun-Ramsay, 1st Marquess of Dalhousie, Lord Dalhousie. There are courses available covering science, commerce and the arts. History Wood's despatch, drafted by Sir Wood in 1854, advocated a range of educational reforms in India, including the establishment of universities in major Indian cities. As such, the University of Bombay was established in 1857 after the presentation of a petiti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Camptothecin
Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the Bark (botany), bark of ''Camptotheca acuminata'' (喜树 "Happy tree"), a tree native to China used in traditional Chinese medicine. It has been used clinically in China for the treatment of gastrointestinal tumors. CPT showed anticancer activity in preliminary clinical trials, especially against breast, ovarian, colon, lung, and stomach cancers. However, it has low solubility and adverse effects have been reported when used therapeutically, so synthetic and medicinal chemists have developed numerous syntheses of camptothecin and various derivatives to increase the benefits of the chemical, with good results. Four CPT Analog (chemistry), analogues have been approved and are used in cancer chemotherapy today: topotecan, irinotecan, belotecan, and trastuzumab deruxtecan. Camptothecin has als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
