Malonic Semialdehyde
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Malonic Semialdehyde
3-Oxopropanoic acid (also malonic semialdehyde or formylacetic acid) is an organic chemical compound that carries both a carboxylic acid function and an aldehyde function. Natural occurence In nature, 3-oxopropanoic acid occurs as a metabolic intermediate. It is formed, for example, by the reversible oxidation of 3-hydroxypropionyl-CoA with nicotinamide adenine dinucleotide (NAD). A bacterial strain of the species ''Pseudomonas fluorescens'' is known to survive on propiolic acid as its sole carbon and energy source. 3-Oxopropanoic acid is an important metabolic intermediate: it is formed by hydration of acetylenic acid and is converted into acetyl-CoA by decarboxylation. It also occurs as a metabolic intermediate in a strain of ''Escherichia coli'' that can grow on uracil as its sole nitrogen source. 3-Oxopropanoic acid also occurs in atmospheric aerosols along with various other organic acids (especially oxalic acid). It has been detected as an aerosol component at various statio ...
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Metabolic Intermediate
Metabolic intermediates are compounds produced during the conversion of substrates (starting molecules) into final products in biochemical reactions within cells. Although these intermediates are of relatively minor direct importance to cellular function, they can play important roles in the allosteric regulation of enzymes, glycolysis, the citric acid cycle, and amino acid synthesis. Metabolic pathways consist of a series of enzymatically catalyzed reactions where each step transforms a substrate into a product that serves as the substrate for the next reaction. Metabolic intermediates are compounds that form during these steps, and they are neither the starting substrate nor the final product of the pathway. These intermediates are crucial because they allow for regulation, energy storage, and extraction of chemical energy in a controlled manner. Types of Metabolic Intermediates Metabolic intermediates can belong to different biochemical classes based on the type o ...
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