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Major Duodenal Papilla
The major duodenal papilla (papilla of Vater) is a rounded projection in the duodenum into which the common bile duct and pancreatic duct drain. The major duodenal papilla is, in most people, the primary mechanism for the secretion of bile and other enzymes that facilitate digestion. Structure The major duodenal papilla is situated in the second part of the duodenum, 7–10 cm from the pylorus, at the level of the second or third lumbar vertebrae. It is surrounded by the sphincter of Oddi, a circular muscle, and receives a mixture of pancreatic enzymes and bile from the Ampulla of Vater, which drains both the pancreatic duct and biliary system. The junction between the foregut and midgut occurs directly below the major duodenal papilla. The major duodenal papilla projects less than a centimetre into the lumen of the duodenum. It appears rounded and is often covered by a fold on the uppermost side of the papilla; that is, the side which receives contents from the stomach. ...
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Duodenum
The duodenum is the first section of the small intestine in most vertebrates, including mammals, reptiles, and birds. In mammals, it may be the principal site for iron absorption. The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine. In humans, the duodenum is a hollow jointed tube about long connecting the stomach to the jejunum, the middle part of the small intestine. It begins with the duodenal bulb, and ends at the duodenojejunal flexure marked by the suspensory muscle of duodenum. The duodenum can be divided into four parts: the first (superior), the second (descending), the third (transverse) and the fourth (ascending) parts. Overview The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms ''anterior intestine'' or ''proximal intestine'' may be used instead of duodenum. In mammals the d ...
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Lumen (anatomy)
In biology, a lumen (: lumina) is the inside space of a tubular structure, such as an artery or intestine. It comes . It can refer to: *the interior of a vessel, such as the central space in an artery, vein or capillary through which blood flows *the interior of the gastrointestinal tract *the pathways of the bronchi in the lungs *the interior of renal tubules and urinary collecting ducts *the pathways of the female genital tract, starting with a single pathway of the vagina, splitting up in two lumina in the uterus, both of which continue through the fallopian tubes *the fluid-filled cavity forming in the blastocyst during pre-implantation development called the blastocoel In cell biology, lumen is a membrane-defined space that is found inside several organelles, cellular components, or structures, including thylakoid, endoplasmic reticulum, Golgi apparatus, lysosome, mitochondrion, and microtubule. Transluminal procedures ''Transluminal procedures'' are procedures occur ...
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Sphincter Of Oddi
The sphincter of Oddi (SO) (also hepatopancreatic sphincter or Glisson's sphincter), is a sphincter, a muscular valve that, in humans and some animals, controls the flow of bile and pancreatic juice out of the gallbladder and pancreas respectively through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi. Structure The sphincter of Oddi is a circular muscle band, or sphincter that surrounds the major duodenal papilla. Function The sphincter regulates the secretion of pancreatic juice and bile into the duodenum. It also prevents reflux of duodenal contents into the ampulla of Vater. By preventing reflux of the contents of the duodenum, the sphincter of Oddi prevents the accumulation of particulate matter and sludge in the bile ducts, reducing the risk of cholangitis. The sphincter of Oddi also allows retrograde filling of the gallbladder. The sphincter of Oddi is relaxed by the hormone cholecystokinin via vasoactive intestinal pep ...
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Abraham Vater
Abraham Vater (9 December 1684 – 18 November 1751) was a German anatomist from Wittenberg. He received his doctorate in philosophy from the University of Wittenberg in 1706, and his medical degree from the University of Leipzig in 1710. Afterwards, he embarked on a scientific trip through Germany, Holland and England. In Amsterdam he met with Frederik Ruysch (1638-1731). He later gained his habilitation in Wittenberg, becoming an associate professor in 1719, a full professor of anatomy in 1732 and a professor of therapy in 1746. Vater is primarily known for his work in anatomy, but he also published works in the fields of chemistry, botany, pharmacology and gynaecology. He was the first to describe the hepatopancreatic ampulla, which is the juncture of the pancreatic duct and the common bile duct, and is now referred to as the ampulla of Vater. In 1719, Vater was the first to notice oval-shaped organs of concentric layers of connective tissue wrapped around nerve endings in ...
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Anatomist
Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its beginnings in prehistoric times. Anatomy is inherently tied to developmental biology, embryology, comparative anatomy, evolutionary biology, and phylogeny, as these are the processes by which anatomy is generated, both over immediate and long-term timescales. Anatomy and physiology, which study the structure and function of organisms and their parts respectively, make a natural pair of related disciplines, and are often studied together. Human anatomy is one of the essential basic sciences that are applied in medicine, and is often studied alongside physiology. Anatomy is a complex and dynamic field that is constantly evolving as discoveries are made. In recent years, there has been a significant increase in the use of ...
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Germany
Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total population of over 84 million in an area of , making it the most populous member state of the European Union. It borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The Capital of Germany, nation's capital and List of cities in Germany by population, most populous city is Berlin and its main financial centre is Frankfurt; the largest urban area is the Ruhr. Settlement in the territory of modern Germany began in the Lower Paleolithic, with various tribes inhabiting it from the Neolithic onward, chiefly the Celts. Various Germanic peoples, Germanic tribes have inhabited the northern parts of modern Germany since classical ...
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Pancreatic Duct
The pancreatic duct or duct of Wirsung (also, the major pancreatic duct due to the existence of an accessory pancreatic duct) is a duct joining the pancreas to the common bile duct. This supplies it with pancreatic juice from the exocrine pancreas, which aids in digestion. Structure The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. There are many anatomical variants reported, but these are quite rare. Accessory pancreatic duct Most people have just one pancreatic duct. However, some have an additional accessory pancreatic duct, also called the Duct of Santorini. An accessory pancreatic duct can be functional or non-functional. It may open separately into the second part of the duodenum,Moore KL, Dalley AF. 2006. Clinically Oriented Anatomy. 5th Ed. Lippincott Williams & Wilkins. p 287.1. Mchonde GJ, Gesase AP. Termination pat ...
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Accessory Pancreatic Duct
Accessory may refer to: * Accessory (legal term), a person who assists a criminal In anatomy * Accessory bone * Accessory breast * Accessory kidney * Accessory muscle * Accessory nucleus, in anatomy, a cranial nerve nucleus * Accessory nerve * Accessory spleen In arts and entertainment * Accessory (band), with members Dirk Steyer and Ivo Lottig * Video game accessory, a piece of hardware used in conjunction with a video game console for playing video games * ''Accessories'' (album), a compilation album from Dutch alternative rock band The Gathering * Accessory, a type of rulebook in ''Dungeons & Dragons'' and other role-playing games Other uses * Fashion accessory, an item used to complement a fashion or style * Accessory suite, a secondary dwelling on a parcel of land * Rental accessories and attachments, accessories used in the rental industry * Cable accessories for connecting and terminating cables * Accessory fruit, in which some of the flesh is derived from tissues othe ...
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Minor Duodenal Papilla
The minor duodenal papilla is the opening of the accessory pancreatic duct into the descending second section of the duodenum. Structure The minor duodenal papilla is contained within the second part of the duodenum. It is situated 2 cm proximal to the major duodenal papilla, and thus 5–8 cm from the opening of the pylorus. The gastroduodenal artery lies posterior. Variation The minor duodenal papilla may or may not contain a functioning sphincter and patent duct. When present, the sphincter is known as the ''sphincter of Helly'', and the duct as the '' accessory pancreatic duct of Santorini''. In 10% of people, the minor duodenal papilla is the prime duct for drainage of the pancreas, although in others it may not be present at all. Pain from the region will be referred to the epigastric region of the abdomen due to its associated dermatomes. Function The duct is an embryological remnant, however in a small majority of people drains the pancreas. It is present in ...
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Mucosa
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It is mostly of endodermal origin and is continuous with the skin at body openings such as the eyes, eyelids, ears, inside the nose, inside the mouth, lips, the genital areas, the urethral opening and the anus. Some mucous membranes secrete mucus, a thick protective fluid. The function of the membrane is to stop pathogens and dirt from entering the body and to prevent bodily tissues from becoming dehydrated. Structure The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. Mucous membranes line the digestive, respiratory and rep ...
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Midgut
The midgut is the portion of the human embryo from which almost all of the small intestine and approximately half of the large intestine develop. After it bends around the superior mesenteric artery, it is called the "midgut loop". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon. In addition to representing an important distinction in embryologic development, the tissues derived from the midgut additionally have distinct vascular supply and innervation patterns in the adult gastrointestinal system. In the embryo During standard human embryonic development, the midgut undergoes a process known as physiological herniation around week 6, when rapid growth forces the midgut to temporarily exit the abdominal cavity and reside in the extra-abdominal umbilical cord. At this stage, the midgut begins its initial counterclockwise rotation around the ...
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