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Madagascar Henipavirus
Madagascar henipavirus (MadV) is a poorly characterized henipavirus type. Currently it has only been detected serologically among Madagascan rousettes. High cross reactivity was observed with Hendra and Nipah NIPA, Nipa or nipah may refer to: * Shamim Ara Nipa, Bangladeshi dancer and choreographer * Nipah~, an onomatopoeia frequently used by Furude Rika, a character in the Japanese visual novel Higurashi When They Cry * Nipa hut, a type of stilt house ... henipaviruses. References Henipavirus {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henipavirus
''Henipavirus'' is a genus of negative-strand RNA viruses in the family ''Paramyxoviridae'', order ''Mononegavirales'' containing five established species, and numerous others still under study. Henipaviruses are naturally harboured by several species of small mammals, notably Pteropus, pteropid fruit bats (flying foxes), microbats of several species, and shrews. Henipaviruses are characterised by long genomes and a wide host range. Their recent emergence as zoonosis, zoonotic pathogens capable of causing illness and death in domestic animals and humans is a cause of concern. In 2009, RNA sequences of three novel viruses in phylogenetic relationship to known henipaviruses were detected in African straw-colored fruit bats (''Eidolon helvum'') in Ghana. The finding of these novel henipaviruses outside Australia and Asia indicates that the region of potential endemicity of henipaviruses may be worldwide. These African henipaviruses are slowly being characterised. Nipah virus and He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotype
A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or Cell (biology), cells are classified together based on their shared reactivity between their surface antigens and a particular antiserum, allowing the classification of organisms to a Infraspecific name, level below the species. A group of serovars with common antigens is called a serogroup or sometimes ''serocomplex''. Serotyping often plays an essential role in determining species and subspecies. The ''Salmonella'' genus of bacteria, for example, has been determined to have over 2600 serotypes. ''Vibrio cholerae'', the species of bacteria that causes cholera, has over 200 serotypes, based on cell antigens. Only two of them have been observed to produce the potent enterotoxin that results in cholera: O1 and O139. Serotypes were discovered in hemolytic streptococci by the American microbiologist Rebecca Lancefield i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ELISA
The enzyme-linked immunosorbent assay (ELISA) (, ) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971. The assay is a solid-phase type of enzyme immunoassay (EIA) to detect the presence of a ligand (commonly an amino acid) in a liquid sample using antibodies directed against the ligand to be measured. ELISA has been used as a medical diagnosis, diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries. In the most simple form of an ELISA, antigens from the sample to be tested are attached to a surface. Then, a matching antibody is applied over the surface so it can bind the antigen. This antibody is linked to an enzyme, and then any unbound antibodies are removed. In the final step, a substance containing the enzyme's Enzyme substrate, substrate is added. If there was binding, the subsequent reaction produces a detectable signal, most commonly a color change. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Madagascan Rousette
The Madagascan rousette (''Rousettus madagascariensis'') or Madagascar rousette, is a species of megabat in the family Pteropodidae endemic to Madagascar. Its natural habitat is subtropical or tropical dry forests. Description The Madagascan rousette is a small fruit bat, the smallest of the three fruit bats endemic to Madagascar. The upper part of their bodies have a greyish fur while the underparts have a paler grey tinge. Like many other fruit bats, Madagascan rousettes have very dog-like faces with long, pointed snouts, large, wide eyes and largely separated ears. Like some other members of the genus ''Rousettus'', these bats reside within cave roosts, suggesting the use of echolocation. These bats are a part of a larger group of fruit bats within ''Rousettus'' which consists of 10 different species. The Madagascan rousette primarily resides on western islands of the Indian Ocean. Ecology Habitat The habitat of the Madagascan rousette is generally found to be associate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cross-reactivity
Cross-reactivity, in a general sense, is the reactivity of an observed agent which initiates reactions outside the main reaction expected. This has implications for any kind of test or assay, including diagnostic tests in medicine, and can be a cause of false positives. In immunology, the definition of cross-reactivity refers specifically to the reaction of the immune system to antigens. There can be cross-reactivity between the immune system and the antigens of two different pathogens, or between one pathogen and proteins on non-pathogens, which in some cases can be the cause of allergies. In medical testing In medical tests, including rapid diagnostic tests, cross-reactivity can be either confounding or helpful, depending on the instance. An example of confounding that yields a false positive error is in a latex fixation test when agglutination occurs with another antigen rather than the antigen of interest. An example of helpful cross-reactivity is in heterophile antibody ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hendra Virus
Hendra virus (''Henipavirus hendraense'') is a zoonotic virus found solely in Australia. First isolated in 1994, the virus has since been connected to numerous outbreaks of disease in domestic horses and seven human cases. Hendra virus belongs to the genus '' Henipavirus'', which also contains the zoonotic Nipah virus. The reservoir species of Hendra virus are four species of bat within the genus ''Pteropus'' native to Australia. Pathology The Pteropus fruit-eating bats, commonly known as flying foxes, experimentally infected with the Hendra virus develop a viraemia and shed the virus in their urine, faeces and saliva for approximately one week. There is no other indication of an illness in them. Symptoms of Hendra virus infection of humans may be respiratory, including hemorrhage and edema of the lungs, or in some cases viral meningitis. In horses, infection usually causes one or more of pulmonary oedema, congestion and neurological signs. Ephrin B2 has been identified as the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nipah Virus
Nipah virus (''Henipavirus nipahense'') is a bat-borne, Zoonosis, zoonotic virus that causes Nipah virus infection in humans and other animals, a disease with a very high mortality rate (40-75%). Numerous disease outbreaks caused by Nipah virus have occurred in South East Africa and Southeast Asia. Nipah virus belongs to the genus ''Henipavirus'' along with the Hendra virus, which has also caused disease outbreaks. Virology Like other henipaviruses, the Nipah virus genome is a single (non-segmented) negative-sense, single-stranded RNA of over 18 kb, which is substantially longer than that of other Paramyxoviridae, paramyxoviruses. The viral envelope, enveloped virus particles are variable in shape, and can be filamentous or spherical; they contain a helical nucleocapsid. Six structural proteins are generated: N (nucleocapsid), P (phosphoprotein), M (matrix), F (fusion), G (glycoprotein) and L (RNA polymerase). The ''P'' open reading frame also encodes three nonstructural pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henipavirus
''Henipavirus'' is a genus of negative-strand RNA viruses in the family ''Paramyxoviridae'', order ''Mononegavirales'' containing five established species, and numerous others still under study. Henipaviruses are naturally harboured by several species of small mammals, notably Pteropus, pteropid fruit bats (flying foxes), microbats of several species, and shrews. Henipaviruses are characterised by long genomes and a wide host range. Their recent emergence as zoonosis, zoonotic pathogens capable of causing illness and death in domestic animals and humans is a cause of concern. In 2009, RNA sequences of three novel viruses in phylogenetic relationship to known henipaviruses were detected in African straw-colored fruit bats (''Eidolon helvum'') in Ghana. The finding of these novel henipaviruses outside Australia and Asia indicates that the region of potential endemicity of henipaviruses may be worldwide. These African henipaviruses are slowly being characterised. Nipah virus and He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
