|
MFAP (other)
MFAP may stand for: * MFAP1, Microfibrillar-associated protein 1 * MFAP2, Microfibrillar-associated protein 2 * MFAP3, Microfibrillar-associated protein 3 * MFAP4 MFAP4 (microfibril-associated glycoprotein 4) is an extracellular matrix protein encoded by the ''MFAP4'' gene. It is part of the MFAP family of proteoglycans, which are involved in cell adhesion, intercellular interactions and the assembly and/or ..., Microfibrillar-associated protein 4 * MFAP5, Microfibrillar-associated protein 5 {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MFAP1
Microfibrillar-associated protein 1 is a protein that in humans is encoded by the ''MFAP1'' gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei .... References Further reading * * * * * * * {{gene-15-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MFAP2
Microfibrillar-associated protein 2 is a protein that in humans is encoded by the ''MFAP2'' gene. Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. This gene encodes two transcripts with two alternatively spliced 5' untranslated exon An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term ''exon'' refers to both the DNA sequence within a gene and to the corresponding sequence ...s. These two transcripts contain the same eight coding exons, and therefore, encode the same protein. References Further reading * * * * * * * * * * * * * * * * * {{gene-1-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MFAP4
MFAP4 (microfibril-associated glycoprotein 4) is an extracellular matrix protein encoded by the ''MFAP4'' gene. It is part of the MFAP family of proteoglycans, which are involved in cell adhesion, intercellular interactions and the assembly and/or maintenance of elastic fibres. MFAP4 is known to co-localise at sites rich in elastic fibres and is thought to interact with several proteins including FBN1, FBN2, tropoelastin and desmosine. It has a relatively non-specific tissue expression pattern, with higher levels observed in organs such as the lungs and vasculature. __TOC__ Clinical relevance Using MFAP4-deficient mouse models, studies have shown roles for MFAP4 in neointima formation and asthma. Moreover, it has recently been shown that the glycosylation of MFAP4 is raised in the aortic extracellular matrix of Marfan syndrome patients using proteomics and gene expression levels of MFAP4 correlate with alterations in extracellular matrix genes within human aortic vascular smo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |