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Luteolin-7-O-beta-D-glucuronide
Luteolin-7-''O''-glucuronide is a chemical compound that is classified as a flavone. It is found in ''Acanthus hirsutus'' and in rye (''Secale cereale''). Metabolism Luteolin 7-O-glucuronosyltransferase is an enzyme that uses UDP-glucuronate and luteolin to produce UDP and luteolin 7-O-beta-D-glucuronide. Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase is an enzyme that uses UDP-glucuronate and luteolin 7-O-beta-D-glucuronide to produce UDP and luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide). References Flavone glycosides Flavonoid glucuronides Glucuronide esters {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method that animals use to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; bloo ...s. Enzymes that cleave the glycosidic bond of a glucuronide are called glucuronidases. Examples * Miquelianin ( Quercetin 3-O-glucur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element is therefore not a compound. A compound can be transformed into a different substance by a chemical reaction, which may involve interactions with other substances. In this process, bonds between atoms may be broken and/or new bonds formed. There are four major types of compounds, distinguished by how the constituent atoms are bonded together. Molecular compounds are held together by covalent bonds; ionic compounds are held together by ionic bonds; intermetallic compounds are held together by metallic bonds; coordination complexes are held together by coordinate covalent bonds. Non-stoichiometric compounds form a disputed marginal case. A chemical formula specifies the number of atoms of each element in a compound molecule, usi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flavone
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone. Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon .... References {{Flavones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acanthus Hirsutus
''Acanthus hirsutus'' is a species of flowering plant in the Acanthaceae family. It contains the glycosides hirsutusoide (2-(o-hydroxyphenyl)-2-hydroxyethenyl-O-beta-glucopyranoside), luteolin-7-O-beta-D-glucuronide Luteolin-7-''O''-glucuronide is a chemical compound that is classified as a flavone. It is found in ''Acanthus hirsutus'' and in rye (''Secale cereale''). Metabolism Luteolin 7-O-glucuronosyltransferase is an enzyme that uses UDP-glucuronate a ..., beta-sitosterol-3-O-beta-D-glucopyranoside and (2R)-2-O-beta-D-glucopyranosyl-2H-1,4-benzoxazin-3(4H)-one. References External links hirsutus Taxa named by Pierre Edmond Boissier {{Acanthaceae-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin 7-O-glucuronosyltransferase
In enzymology, a luteolin 7-O-glucuronosyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-glucuronate + luteolin \rightleftharpoons UDP + luteolin 7-O-beta-D-glucuronide Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin, whereas its two products are UDP and luteolin 7-O-beta-D-glucuronide. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is UDP-glucuronate:luteolin 7-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase, and LGT. References * EC 2.4.1 Enzymes of unknown structure {{2.4-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UDP-glucuronate
UDP-glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid (except in primates and guinea pigs). It is made from UDP-glucose by UDP-glucose 6-dehydrogenase (EC 1.1.1.22) using NAD+ as a cofactor. It is the source of the glucuronosyl group in glucuronosyltransferase reactions. See also * Glucuronic acid Glucuronic acid (from Greek γλεῦκος "''wine, must''" and οὖρον "''urine''") is a uronic acid that was first isolated from urine (hence the name). It is found in many gums such as gum arabic (c. 18%), xanthan, and kombucha tea ... * UDP References Glucuronide esters Coenzymes Nucleotides {{biochem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase
In enzymology, a luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-glucuronate + luteolin 7-O-beta-D-glucuronide \rightleftharpoons UDP + luteolin 7-O- eta-D-glucuronosyl-(1→2)-beta-D-glucuronide Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin 7-O-beta-D-glucuronide, whereas its two products are UDP and luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide). This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin 7-O-(beta-D-glucuronosyl-(1→2)-beta-D-glucuronide)
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia tom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flavone Glycosides
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone. Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon .... References {{Flavones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flavonoid Glucuronides
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4-benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
