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Lupus Pernio
Lupus pernio is a chronic raised indurated (hardened) lesion of the skin, often purplish in color. It is seen on the nose, ears, cheeks, lips, and forehead. It is pathognomonic of sarcoidosis. The name "lupus pernio" is a misnomer, as microscopically this disease shows granulomatous infiltration and does not have features of either lupus nor pernio. Signs and symptoms The hallmarks of lupus pernio are violaceous or erythematous, indurated plaques that are mostly found on the cheeks and nose in the center of the face. Rarely, lesions may also affect the dorsum of the hands and feet and the ears. The symptoms of lupus pernio range from a few tiny nodules on the nose to vibrant plaques that cover both cheeks. Lupus pernio lesions begin slowly but eventually penetrate and indurate into the underlying bone and cartilage, resulting in deformity. There is a higher chance of extracutaneous involvement, especially in the respiratory tract, in lupus pernio. Causes The cause of cutane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarcoidosis
Sarcoidosis (; also known as Besnier–Boeck–Schaumann disease) is a disease involving abnormal collections of White blood cell, inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly affected are the eyes, liver, heart, and Human brain, brain, though any Organ (anatomy), organ can be affected. The signs and symptoms depend on the organ involved. Often, no symptoms or only mild symptoms are seen. When it affects the lungs, wheezing, coughing, shortness of breath, or chest pain may occur. Some may have Löfgren syndrome with fever, Bilateral hilar lymphadenopathy, enlarged hilar lymph nodes, arthritis, and a rash known as erythema nodosum. The cause of sarcoidosis is unknown. Some believe it may be due to an immune reaction to a trigger such as an infection or chemicals in those who are genetically predisposed. Those with affected family members are at greater risk. Diagnosis is partly based on signs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dermatology
Dermatology is the branch of medicine dealing with the Human skin, skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A List of dermatologists, dermatologist is a specialist medical doctor who manages diseases related to skin. Etymology Attested in English in 1819, the word "dermatology" derives from the Ancient Greek, Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία ''wikt:-logia, -logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases (Jean-Louis-Marc Alibert, Alibert's, 1806–1816) appeared in print around the same time.Freedber ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronic (medicine)
A chronic condition (also known as chronic disease or chronic illness) is a health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time. The term ''chronic'' is often applied when the course of the disease lasts for more than three months. Common chronic diseases include diabetes, functional gastrointestinal disorder, eczema, arthritis, asthma, chronic obstructive pulmonary disease, autoimmune diseases, genetic disorders and some viral diseases such as hepatitis C and acquired immunodeficiency syndrome. An illness which is lifelong because it ends in death is a terminal illness. It is possible and not unexpected for an illness to change in definition from terminal to chronic as medicine progresses. Diabetes and HIV for example were once terminal yet are now considered chronic, due to the availability of insulin for diabetics and daily drug treatment for individuals with HIV, which allow these individuals to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by injury or diseases. The term ''Lesion'' is derived from the Latin meaning "injury". Lesions may occur in both plants and animals. Types There is no designated classification or naming convention for lesions. Because lesions can occur anywhere in the body and their definition is so broad, the varieties of lesions are virtually endless. Generally, lesions may be classified by their patterns, sizes, locations, or causes. They can also be named after the person who discovered them. For example, Ghon lesions, which are found in the lungs of those with tuberculosis, are named after the lesion's discoverer, Anton Ghon. The characteristic skin lesions of a varicella zoster virus infection are called '' chickenpox''. Lesions of the teeth are usually called dental caries, or "cavities". Location Lesions are often classified by their tissue types or locations. For example, "skin lesions" or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Nose
The human nose is the first organ of the respiratory system. It is also the principal organ in the olfactory system. The shape of the nose is determined by the nasal bones and the nasal cartilages, including the nasal septum, which separates the nostrils and divides the nasal cavity into two. The nose has an important function in breathing. The nasal mucosa lining the nasal cavity and the paranasal sinuses carries out the necessary conditioning of inhaled air by warming and moistening it. Nasal conchae, shell-like bones in the walls of the cavities, play a major part in this process. Filtering of the air by nasal hair in the nostrils prevents large particles from entering the lungs. Sneezing is a reflex to expel unwanted particles from the nose that irritate the mucosal lining. Sneezing can Transmission (medicine), transmit infections, because aerosols are created in which the Respiratory droplets, droplets can harbour pathogens. Another major function of the nose is olfactio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cheek
The cheeks () constitute the area of the face below the eyes and between the nose and the left or right ear. ''Buccal'' means relating to the cheek. In humans, the region is innervated by the buccal nerve. The area between the inside of the cheek and the teeth and gums is called the vestibule or ''buccal'' pouch or ''buccal'' cavity and forms part of the mouth. In other animals, the cheeks may also be referred to as " jowls". Structure Cheeks are fleshy in humans, the skin being suspended by the chin and the jaws, and forming the lateral wall of the human mouth, visibly touching the cheekbone below the eye. The inside of the cheek is lined with a mucous membrane (''buccal'' mucosa, part of the oral mucosa). During mastication (chewing), the cheeks and tongue between them serve to keep the food between the teeth. Clinical significance The cheek is the most common location from which a DNA sample can be taken. (Some saliva is collected from inside the mouth, e.g. using a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Forehead
In human anatomy, the forehead is an area of the head bounded by three features, two of the skull and one of the scalp. The top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows. The bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes. The two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond. However, the eyebrows do not form part of the forehead. In '' Terminologia Anatomica'', ''sinciput'' is given as the Latin equivalent to "forehead" (etymology of ''sinciput'': from ''semi-'' "half" and ''caput'' "head".). Structure The bone of the forehead is the squamous part of the frontal bone. The overlying muscles are the occipitofrontalis, procerus, and corrugator supercilii muscles, all of which are controlled by the temporal branch of the facial nerve. The sensory nerves of the forehea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathognomonic
Pathognomonic (synonym ''pathognomic'') is a term, often used in medicine, that means "characteristic for a particular disease". A pathognomonic sign is a particular sign whose presence means that a particular disease is present beyond any doubt. The absence of a pathognomonic sign does not rule out the disease. Labelling a sign or symptom "pathognomonic" represents a marked intensification of a "diagnostic" sign or symptom. The word is an adjective of Greek origin derived from πάθος ''pathos'' 'disease' and γνώμων ''gnomon'' 'indicator' (from γιγνώσκω ''gignosko'' 'I know, I recognize'). Practical use While some findings may be classic, typical or highly suggestive in a certain condition, they may not occur ''uniquely'' in this condition and therefore may not directly imply a specific diagnosis. A pathognomonic sign or symptom has very high positive predictive value and high specificity but does not need to have high sensitivity: for example it can som ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Misnomer
A misnomer is a name that is incorrectly or unsuitably applied. Misnomers often arise because something was named long before its correct nature was known, or because an earlier form of something has been replaced by a later form to which the name no longer suitably applies. A misnomer may also be a word that is used incorrectly or misleadingly. The word "misnomer" does not mean " misunderstanding" or " popular misconception", and a number of misnomers remain in common usage — which is to say that a word being a misnomer does not necessarily make ''usage'' of the word incorrect. Sources of misnomers * An older name being retained after the thing itself has changed (e.g., tin can, mince meat pie, steamroller, tin foil, clothes iron, digital darkroom). This is essentially a metaphorical extension with the name of the older item standing for anything filling the same role. * Transference of a well-known product brand name into a genericized trademark (e.g., Xerox f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lupus
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary among people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus. The cause of SLE is not clear. It is thought to involve a combination of genetics and environmental factors. Among identical twins, if one is affected there is a 24% chance the other one will also develop the disease. Female sex hormones, sunlight, smoking, vitamin D deficiency, and certain infections are also believed to increase a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarcoidosis
Sarcoidosis (; also known as Besnier–Boeck–Schaumann disease) is a disease involving abnormal collections of White blood cell, inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly affected are the eyes, liver, heart, and Human brain, brain, though any Organ (anatomy), organ can be affected. The signs and symptoms depend on the organ involved. Often, no symptoms or only mild symptoms are seen. When it affects the lungs, wheezing, coughing, shortness of breath, or chest pain may occur. Some may have Löfgren syndrome with fever, Bilateral hilar lymphadenopathy, enlarged hilar lymph nodes, arthritis, and a rash known as erythema nodosum. The cause of sarcoidosis is unknown. Some believe it may be due to an immune reaction to a trigger such as an infection or chemicals in those who are genetically predisposed. Those with affected family members are at greater risk. Diagnosis is partly based on signs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
