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Luisa DiPietro
Luisa DiPietro is a faculty member at the University of Illinois at Chicago College of Dentistry. She is Director of the Center for Wound Repair and Tissue Regeneration and a Professor of Periodontics for the College. DiPietro's interests in wound healing focus on the effects of aging and inflammation on scarring during healing. She investigates critical differences in inflammation and angiogenesis between oral versus cutaneous wounds that ultimately result in rapid, nonscarring healing in mucosa. From 2010 to 2011, she served as the president of the Wound Healing Society. In 2015, she was named a University Scholar of the University of Illinois. DiPietro received her PhD in immunology and DDS from the University of Illinois at Chicago The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois, United States. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the Univer ...
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University Of Illinois At Chicago
The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois, United States. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the University of Illinois system, UIC is also the largest university in the Chicago metropolitan area, having more than 33,000 students enrolled in 16 colleges. It is classified among "R1: Doctoral Universities – Very high research activity." UIC competes in NCAA Division I Missouri Valley Conference. History Beginnings The University of Illinois Chicago traces its origins to several health colleges founded during the late 19th century, including the Chicago College of Pharmacy, which opened in 1859, the College of Physicians and Surgeons (1882), and the Columbian College of Dentistry (1893). The University of Illinois was chartered in 1867 in Champaign-Urbana, as the state's land-grant university. In exchange for agreeing to the Champaign-Ur ...
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University Of Illinois At Urbana-Champaign
The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United States. Established in 1867, it is the founding campus and flagship institution of the University of Illinois System. With over 59,000 students, the University of Illinois is one of the largest public universities by enrollment in the United States. The university contains 16 schools and colleges and offers more than 150 undergraduate and over 100 graduate programs of study. The university holds 651 buildings on and its annual operating budget in 2016 was over $2 billion. The University of Illinois Urbana-Champaign also operates a research park home to innovation centers for over 90 start-up companies and multinational corporations. The University of Illinois Urbana-Champaign is a member of the Association of American Universities and is classified among "R1: Doctoral Univ ...
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Loyola University Medical Center
Loyola Medicine, also known as Loyola University Health System, is a quaternary-care system with a main medical center campus in the western suburbs of Chicago, in the U.S. state of Illinois. The medical center campus is located in Maywood, west of the Chicago Loop and east of Oak Brook. The heart of the medical center campus is the Loyola University Medical Center. Also on campus are the Joseph Cardinal Bernardin Cancer Center (now named for the late Cardinal Joseph Louis Bernardin, Archbishop of Chicago, who was a patient at the Cancer Center when he died in November 1996 from metastatic pancreatic cancer) Loyola Outpatient Center, Center for Heart & Vascular Medicine and Loyola Oral Health Center as well as the Loyola University Chicago Stritch School of Medicine (named for Samuel Cardinal Stritch, a former archbishop of Chicago), Loyola University Chicago Marcella Niehoff School of Nursing, Center for Translational Research and Education, and the Loyola Center for Fit ...
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University Of Illinois At Chicago College Of Dentistry
The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois, United States. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the University of Illinois system, UIC is also the largest university in the Chicago metropolitan area, having more than 33,000 students enrolled in 16 colleges. It is classified among "R1: Doctoral Universities – Very high research activity." UIC competes in NCAA Division I Missouri Valley Conference. History Beginnings The University of Illinois Chicago traces its origins to several health colleges founded during the late 19th century, including the Chicago College of Pharmacy, which opened in 1859, the College of Physicians and Surgeons (1882), and the Columbian College of Dentistry (1893). The University of Illinois was chartered in 1867 in Champaign-Urbana, as the state's land-grant university. In exchange for agreeing to the Champaign-Ur ...
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Periodontics
Periodontology or periodontics (from Ancient Greek , – 'around'; and , – 'tooth', genitive , ) is the specialty of dentistry that studies supporting structures of teeth, as well as diseases and conditions that affect them. The supporting tissues are known as the periodontium, which includes the gingiva (gums), alveolar bone, cementum, and the periodontal ligament. A periodontist is a dentist that specializes in the prevention, diagnosis and treatment of periodontal disease and in the placement of dental implants. The periodontium The term ''periodontium'' is used to describe the group of structures that directly surround, support and protect the teeth. The periodontium is composed largely of the gingival tissue and the supporting bone. Gingivae Normal gingiva may range in color from light coral pink to heavily pigmented. The soft tissues and connective fibres that cover and protect the underlying cementum, periodontal ligament and alveolar bone are known as the gingiv ...
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Wound Healing
Wound healing refers to a living organism's replacement of destroyed or damaged tissue by newly produced tissue. In undamaged skin, the epidermis (surface, epithelial layer) and dermis (deeper, connective layer) form a protective barrier against the external environment. When the barrier is broken, a regulated sequence of biochemical events is set into motion to repair the damage. This process is divided into predictable phases: blood clotting (hemostasis), inflammation, tissue growth ( cell proliferation), and tissue remodeling (maturation and cell differentiation). Blood clotting may be considered to be part of the inflammation stage instead of a separate stage. The wound-healing process is not only complex but fragile, and it is susceptible to interruption or failure leading to the formation of non-healing chronic wounds. Factors that contribute to non-healing chronic wounds are diabetes, venous or arterial disease, infection, and metabolic deficiencies of old age.Enoch, ...
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Aging
Ageing (or aging in American English) is the process of becoming Old age, older until death. The term refers mainly to humans, many other animals, and fungi; whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have Cellular senescence, ceased dividing, or to the Population ageing, population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Current Theory of aging, ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the p ...
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Inflammation
Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', ''dolor'', ''rubor'', ''tumor'', and ''functio laesa''). Inflammation is a generic response, and therefore is considered a mechanism of innate immunity, whereas adaptive immunity is specific to each pathogen. Inflammation is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out damaged cells and tissues, and initiate tissue repair. Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. However inflammation can also have negative effects. Too much inflammation, in the form of chronic inflammation, is associated with variou ...
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Scarring
A scar (or scar tissue) is an area of fibrous tissue that replaces normal skin after an injury. Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. Thus, scarring is a natural part of the healing process. With the exception of very minor lesions, every wound (e.g., after accident, disease, or surgery) results in some degree of scarring. An exception to this are animals with complete regeneration, which regrow tissue without scar formation. Scar tissue is composed of the same protein (collagen) as the tissue that it replaces, but the fiber composition of the protein is different; instead of a random basketweave formation of the collagen fibers found in normal tissue, in fibrosis the collagen cross-links and forms a pronounced alignment in a single direction. This collagen scar tissue alignment is usually of inferior functional quality to the normal collagen randomised alignment. For example, scars in the ...
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Healing
With physical trauma or disease suffered by an organism, healing involves the repairing of damaged tissue(s), organs and the biological system as a whole and resumption of (normal) functioning. Medicine includes the process by which the cells in the body regenerate and repair to reduce the size of a damaged or necrotic area and replace it with new living tissue. The replacement can happen in two ways: by ''regeneration'' in which the necrotic cells are replaced by new cells that form "like" tissue as was originally there; or by ''repair'' in which injured tissue is replaced with scar tissue. Most organs will heal using a mixture of both mechanisms. Within surgery, healing is more often referred to as recovery, and postoperative recovery has historically been viewed simply as restitution of function and readiness for discharge. More recently, it has been described as an energy‐requiring process to decrease physical symptoms, reach a level of emotional well‐being, regain ...
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Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and splitting, but processes such as coalescent angiogenesis, vessel elongation and vessel cooption also play a role. Vasculogenesis is the embryonic formation of endothelial cells from mesoderm cell precursors, and from neovascularization, although discussions are not always precise (especially in older texts). The first vessels in the developing embryo form through vasculogenesis, after which angiogenesis is responsible for most, if not all, blood vessel growth during development and in disease. Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue. However, it is also a fundamental step in the transition of tumors from a benign state to a malign ...
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Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ...
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