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Luis Leloir
Luis Federico Leloir (September 6, 1906 – December 2, 1987) was an Argentine physician and biochemist who received the 1970 Nobel Prize in Chemistry for his discovery of the metabolic pathways by which carbohydrates are synthesized and converted into energy in the body. Although born in France, Leloir received the majority of his education at the University of Buenos Aires and was director of the private research group Fundación Instituto Campomar until his death in 1987. His research into sugar nucleotides, carbohydrate metabolism, and renal hypertension garnered international attention and led to significant progress in understanding, diagnosing and treating the congenital disease galactosemia. Leloir is buried in La Recoleta Cemetery, Buenos Aires. Biography Early years Leloir's parents, Federico Augusto Rufino and Hortencia Aguirre de Leloir, traveled from Buenos Aires to Paris in the middle of 1906 with the intention of treating Federico's illness. However, Federi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paris
Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of cities in the European Union by population within city limits, fourth-most populous city in the European Union and the List of cities proper by population density, 30th most densely populated city in the world in 2022. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, culture, Fashion capital, fashion, and gastronomy. Because of its leading role in the French art, arts and Science and technology in France, sciences and its early adoption of extensive street lighting, Paris became known as the City of Light in the 19th century. The City of Paris is the centre of the Île-de-France region, or Paris Region, with an official estimated population of 12,271,794 inhabitants in January 2023, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mar De Ajó
Mar de Ajó is a coastal city in Buenos Aires Province, Argentina, and is located in the southern end of the seaside La Costa Partido (the Coast District). The region is known as the Tuju Corner (Rincón del Tuyú). Etymology It owes its name to a word used by the Guarani aborigines who inhabited the area, whose meaning is ''Soft Mud''. During the arrival in 1580 of the Paraguayan Hernando Arias de Saavedra to the shores of the mouth of the Río de la Plata with the Atlantic Ocean, his expedition made use of the collaboration of a group of evangelized Guarani indigenous people, who identified this area with the word ''Tuju'', a term in Guarani that indicated the presence of white mud on the coasts and bottom of the river, for this reason, this place ended up being known as the Rincón del Tuyú. There's the Ria Ajó, which was identified by the Guarani with the term ''Ajo'', which alluded to the soft white mud of its bed, which made the terrain unstable when it came to traversin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Clemente Del Tuyú
San Clemente del Tuyú is an Argentina, Argentine town in the ''La Costa Partido, Partido de la Costa'' district of the Province of Buenos Aires. History Noticed by Ferdinand Magellan in 1520, who gave nearby Cape San Antonio, Argentina, Cape San Antonio its name, Spanish authorities first surveyed the area in 1580. Led by reformist Governor Hernando Arias de Saavedra, his Guarani people, Guaraní staff christened the spot ''Rincón del Tuyú'' ("muddy corner"). First mapped by United Kingdom, British Society of Jesus, Jesuit Thomas Falkner in 1744, the neighboring stream was named ''San Clemente'' by Spain, Spanish Jesuit José Cardiel. The waterfront area was soon purchased by the Ortiz de Rozas family, one of Argentina's most well-established landowners. Sold to another prominent family, the Leloirs, in 1816, the area became a sheep ranch. A descendant of the Ortiz de Rozas', General Juan Manuel de Rosas, had the area incorporated into a district of the Province of Buenos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spain
Spain, or the Kingdom of Spain, is a country in Southern Europe, Southern and Western Europe with territories in North Africa. Featuring the Punta de Tarifa, southernmost point of continental Europe, it is the largest country in Southern Europe and the fourth-most populous European Union member state. Spanning across the majority of the Iberian Peninsula, its territory also includes the Canary Islands, in the Eastern Atlantic Ocean, the Balearic Islands, in the Western Mediterranean Sea, and the Autonomous communities of Spain#Autonomous cities, autonomous cities of Ceuta and Melilla, in mainland Africa. Peninsular Spain is bordered to the north by France, Andorra, and the Bay of Biscay; to the east and south by the Mediterranean Sea and Gibraltar; and to the west by Portugal and the Atlantic Ocean. Spain's capital and List of largest cities in Spain, largest city is Madrid, and other major List of metropolitan areas in Spain, urban areas include Barcelona, Valencia, Seville, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basque Country (historical Territory)
The Basque Country (; ; ) is the name given to the home of the Basque people. Trask, R.L. ''The History of Basque'' Routledge: 1997 The Basque Country is located in the western Pyrenees, straddling the border between France and Spain on the coast of the Bay of Biscay. Encompassing the Autonomous Communities of the Basque Country and Navarre in Spain and the Northern Basque Country in France, the region is home to the Basque people (), their language (), culture and traditions. The area is neither linguistically nor culturally homogeneous, and certain areas have a majority of people who do not consider themselves Basque, such as the south of Navarre. The concept is still highly controversial, and the Supreme Court of Navarre has upheld a denial of government funding to school books that include the Navarre community within the Basque Country area. Etymology The name in Basque is ''Euskal Herria''. The name is difficult to accurately translate into other languages due to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arc De Triomphe
The Arc de Triomphe de l'Étoile, often called simply the Arc de Triomphe, is one of the most famous monuments in Paris, France, standing at the western end of the Champs-Élysées at the centre of Place Charles de Gaulle, formerly named Place de l'Étoile—the ''étoile'' or "star" of the juncture formed by its twelve radiating avenues. The location of the arc and the plaza is shared between three Arrondissements of Paris, arrondissements, 16th arrondissement of Paris, 16th (south and west), 17th arrondissement of Paris, 17th (north), and 8th arrondissement of Paris, 8th (east). The Arc de Triomphe honours those who fought and died for France in the French Revolutionary Wars, French Revolutionary and Napoleonic Wars, with the names of all French victories and generals inscribed on its inner and outer surfaces. Beneath its vault lies the Tomb of the Unknown Soldier (France), Tomb of the Unknown Soldier from World War I. The central cohesive element of the ''Axe historique'' ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
La Recoleta Cemetery
La Recoleta Cemetery () is a cemetery located in the Recoleta, Buenos Aires, Recoleta Barrios and Communes of Buenos Aires, neighbourhood of Buenos Aires, Argentina. It contains the graves of notable people, including Eva Perón, President of Argentina, presidents of Argentina, Nobel Prize winners, the founder of the Argentine Navy, and military commanders such as Julio Argentino Roca. In 2011, the BBC hailed it as one of the world's best cemeteries, and in 2013, CNN listed it among the 10 most beautiful cemeteries in the world. History Franciscan Recollect monks () arrived in this area, then the outskirts of Buenos Aires, in the early eighteenth century. The cemetery is built around the Recollect Convent () and a church, Basilica of Our Lady of the Pillar, Buenos Aires, Our Lady of the Pillar ('), built in 1732. The order was disbanded in 1822, and the garden of the convent converted into the first public cemetery in Buenos Aires. Inaugurated on 17 November of the same year un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galactosemia
Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetics, genetic Metabolism, metabolic Disease, disorder that affects an individual's ability to metabolize the sugar galactose properly. Galactosemia follows an autosomal recessive mode of inheritance that confers a deficiency in an enzyme responsible for adequate galactose degradation. Friedrich Goppert (1870–1927), a German physician, first described the disease in 1917, with its cause as a defect in galactose metabolism being identified by a group led by Herman Kalckar in 1956. Galactosemia was the second disorder found to be detectable through newborn screening methods by Robert Guthrie. Its incidence is about 1 per 60,000 births for people of European ancestry. In other populations the incidence rate differs. Galactosemia is about one hundred times more common (1:480 births) in the Irish Traveller population. Symptoms and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypertension
Hypertension, also known as high blood pressure, is a Chronic condition, long-term Disease, medical condition in which the blood pressure in the artery, arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide. High blood pressure is classified as essential hypertension, primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to non-specific lifestyle and Genetics, genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, overweight, excess body weight, smoking, physical inactivity and Alcohol (drug), alcohol use. The remaining 5–10% of cases are categorized as secondary hypertension, d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid-base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functiona ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbohydrate
A carbohydrate () is a biomolecule composed of carbon (C), hydrogen (H), and oxygen (O) atoms. The typical hydrogen-to-oxygen atomic ratio is 2:1, analogous to that of water, and is represented by the empirical formula (where ''m'' and ''n'' may differ). This formula does not imply direct covalent bonding between hydrogen and oxygen atoms; for example, in , hydrogen is covalently bonded to carbon, not oxygen. While the 2:1 hydrogen-to-oxygen ratio is characteristic of many carbohydrates, exceptions exist. For instance, uronic acids and deoxy-sugars like fucose deviate from this precise stoichiometric definition. Conversely, some compounds conforming to this definition, such as formaldehyde and acetic acid, are not classified as carbohydrates. The term is predominantly used in biochemistry, functioning as a synonym for saccharide (), a group that includes sugars, starch, and cellulose. The saccharides are divided into four chemical groups: monosaccharides, disaccharides, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
