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Liebermeister's Rule
Liebermeister's rule concerns the increment ratio between an adult individual's cardiac frequency and temperature when in fever. Each Celsius grade of body temperature increment corresponds to an 8 ''beats per minute'' increase in cardiac frequency, although the exact number of this rule varies significantly across different sources. An exception to this rule by creating a relative bradycardia is known as Faget sign (pulse-temperature dissociation) common in some diseases, especially yellow fever, tularaemia and salmonella typhi.It is named for Carl von Liebermeister Carl von Liebermeister (2 February 1833 – 24 December 1901) was a German internist who was a native of Ronsdorf. In 1856 he received his medical degree from Greifswald, and in 1860 became an assistant to Felix von Niemeyer (1820-1871) at the .... References {{Eponymous medical signs for infectious disease Cardiology Medical signs Tropical diseases Viral diseases ...
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Thermoregulation
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature as its own body temperature, thus avoiding the need for internal thermoregulation. The internal thermoregulation process is one aspect of homeostasis: a state of dynamic stability in an organism's internal conditions, maintained far from thermal equilibrium with its environment (the study of such processes in zoology has been called physiological ecology). If the body is unable to maintain a normal temperature and it increases significantly above normal, a condition known as hyperthermia occurs. Humans may also experience lethal hyperthermia when the wet bulb temperature is sustained above for six hours. The opposite condition, when body temperature decreases below normal levels, is known as hypothermia. It results when the homeostati ...
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Bradycardia
Bradycardia (also sinus bradycardia) is a slow resting heart rate, commonly under 60 beats per minute (BPM) as determined by an electrocardiogram. It is considered to be a normal heart rate during sleep, in young and healthy or elderly adults, and in athletes. In some people, bradycardia below 60 BPM may be associated with fatigue, weakness, dizziness, sweating, and fainting. The term "relative bradycardia" is used to refer to a heart rate slower than an individual's typical resting heart rate. Athletes may have athletic heart syndrome, which includes bradycardia as part of the cardiovascular adaptations to training and participation. The word "bradycardia" is from the Greek βραδύς ''bradys'' "slow", and καρδία ''kardia'' "heart". Classification Sinus Atrial bradycardias are divided into three types. The first, respiratory sinus arrhythmia, is usually found in young and healthy adults. Heart rate increases during inhalation and decreases during exhalation. T ...
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Faget Sign
In medicine, the Faget sign—sometimes called sphygmothermic dissociation—is the unusual pairing of fever with bradycardia (slow pulse). (Fever is usually accompanied by tachycardia (rapid pulse), an association known by the eponym " Liebermeister's rule".) The Faget sign is named after Louisiana physician Jean Charles Faget, who studied yellow fever in Louisiana. Faget sign is often seen in: *Yellow fever *Typhoid fever *Brain abscess * Tularaemia *Brucellosis *Colorado tick fever *Some pneumonias - ''Legionella ''Legionella'' is a genus of pathogenic gram-negative bacteria that includes the species '' L. pneumophila'', causing legionellosis (all illnesses caused by ''Legionella'') including a pneumonia-type illness called Legionnaires' disease and a mil ...'' pneumonia and '' Mycoplasma'' pneumonia *Drug fever (e.g. beta-blockers,Neuroimmunomodulation. 1999 Jul-Aug;6(4):305-17. Beta-adrenergic receptor subtype effects on stress fever and thermoregulation. Mayfield KP, Sos ...
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Yellow Fever
Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin. If this occurs, the risk of bleeding and kidney problems is increased. The disease is caused by the yellow fever virus and is spread by the bite of an infected mosquito. It infects humans, other primates, and several types of mosquitoes. In cities, it is spread primarily by '' Aedes aegypti'', a type of mosquito found throughout the tropics and subtropics. The virus is an RNA virus of the genus ''Flavivirus''. The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood-sample testing with polymerase chain reaction is required. A ...
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Carl Von Liebermeister
Carl von Liebermeister (2 February 1833 – 24 December 1901) was a German internist who was a native of Ronsdorf. In 1856 he received his medical degree from Greifswald, and in 1860 became an assistant to Felix von Niemeyer (1820-1871) at the University of Tübingen. In 1864 he became a professor of pathology in Basel, and in 1871 returned to Tübingen as a successor to Dr. Niemeyer. Liebermeister is remembered for his work involving the pathophysiology of fever, and research of anti-pyretic treatments such as hydrotherapy. His name is associated with a dictum dealing with the relationship between the frequency of an individual's pulse and the body's temperature when feverish. " Liebermeister's rule" states that in adult febrile tachycardia, pulse-beats increase at a rate of approximately eight beats per minute to each degree Celsius. Liebermeister was interested in many facets of medicine, publishing articles on a wide array of subjects. Among his better known writings was ...
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Cardiology
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat adult heart disease. Surgical aspects are not included in ca ...
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Medical Signs
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showing on a medical scan. A symptom is something out of the ordinary that is experienced by an individual such as feeling feverish, a headache or other pain or pains in the body. Signs and symptoms Signs A medical sign is an objective observable indication of a disease, injury, or abnormal physiological state that may be detected during a physical examination, examining the patient history, or diagnostic procedure. These signs are visible or otherwise detectable such as a rash or bruise. Medical signs, along with symptoms, assist in formulating diagnostic hypothesis. Examples of signs include elevated blood pressure, nail clubbing of the fingernails or toenails, staggering gait, and arcus senilis and arcus juvenilis of the eyes. Indicat ...
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Tropical Diseases
Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. However, many were present in northern Europe and northern America in the 17th and 18th centuries before modern understanding of disease causation. The initial impetus for tropical medicine was to protect the health of colonial settlers, notably in India under the British Raj. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect bite, which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for most of the diseases listed here, and many do not have cures. Human exploration of tropical r ...
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